BMRB: 17281

Conformational and membrane interactins studies of antimicrobial peptide Alyteserin-1C

Authors

Subasinghage, A.P., Hewage, C.M., Conlon, M.

Assembly

Alyteserin-1C

Entity

1. Alyteserin-1C (polymer, Thiol state: not present), 23 monomers, 2266.680 Da Detail

GLKEIFKAGL GSLVKGIAAH VAS

Formula weight

2266.68 Da

Source organism

Alytes obstetricans

Exptl. method

solution NMR

Refine. method

simulated annealing

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 82.0 %, Completeness (bb): 98.0 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	82.0 % (105 of 128)	82.0 % (105 of 128)
Backbone	98.0 % (49 of 50)	98.0 % (49 of 50)
Sidechain	71.8 % (56 of 78)	71.8 % (56 of 78)
Aromatic	28.6 % (2 of 7)	28.6 % (2 of 7)
Methyl	94.4 % (17 of 18)	94.4 % (17 of 18)

1. Alyteserin-1C

GLKEIFKAGL GSLVKGIAAH VAS

Show sample condition

Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 307 K, pH 3.5, Details DHPC was used as micelles

#	Name	Isotope labeling	Type	Concentration
1	DHPC	natural abundance		290 mM
2	H2O	natural abundance		90 %
3	D2O	natural abundance		10 %
4	Alyteserin-1C	natural abundance		1.54 mM

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Protein Blocks Logo

Calculated from 20 models in PDB: 2L5R, Strand ID: A Detail

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Release date

2011-05-17

Citation

Conformational and membrane interaction studies of the antimicrobial peptide alyteserin-1c and its analogue [E4K]alyteserin-1c
Subasinghage, A.P., Conlon, D., Hewage, J.
Biochim. Biophys. Acta (2011), 1808, 1975-1984, PubMed 21565166 , DOI 10.1016/j.bbamem.2011.04.012 , Abstract

Related entities 1. Alyteserin-1C, : 1 entities Detail

Experiments performed 2 experiments Detail