Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir
Polymer type: polydeoxyribonucleotide
Total | 1H | |
---|---|---|
All | 63.1 % (149 of 236) | 63.1 % (149 of 236) |
Suger, PO4 | 48.2 % (81 of 168) | 48.2 % (81 of 168) |
Nucleobase | 100.0 % (68 of 68) | 100.0 % (68 of 68) |
Aromatic | 100.0 % (48 of 48) | 100.0 % (48 of 48) |
Methyl | 100.0 % (4 of 4) | 100.0 % (4 of 4) |
1. Control DNA duplex chain A
CGCATGCTAC GC2. Control DNA duplex chain B
GCGTAGCATG CGSolvent system 95% H2O/5% D2O, Pressure 1 atm, Temperature 298 K, pH 7.1 (±0.1)
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | DNA duplex, chain_A | natural abundance | 2 mM | |
2 | DNA duplex, chain_B | natural abundance | 2 mM | |
3 | NaCl | natural abundance | 50 mM | |
4 | Na2HPO4 | natural abundance | 20 mM | |
5 | EDTA | natural abundance | 1 mM | |
6 | DSS-d6 | natural abundance | 0.25 mM | |
7 | H2O | natural abundance | 95 % | |
8 | D2O | natural abundance | 5 % |