Structure of the duplex containing HNE derived (6S,8R,11S) gamma-HO-PdG when placed opposite dT
Polymer type: polydeoxyribonucleotide
Total | 1H | |
---|---|---|
All | 51.5 % (121 of 235) | 51.5 % (121 of 235) |
Suger, PO4 | 49.4 % (83 of 168) | 49.4 % (83 of 168) |
Nucleobase | 56.7 % (38 of 67) | 56.7 % (38 of 67) |
Aromatic | 68.8 % (33 of 48) | 68.8 % (33 of 48) |
Methyl | 100.0 % (5 of 5) | 100.0 % (5 of 5) |
1. DNA (5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3')
GCTAGCGAGT CC2. DNA (5'-D(*GP*GP*AP*CP*TP*TP*GP*CP*TP*AP*GP*C)-3')
GGACTTGCTA GCSolvent system 100% D2O, Pressure 1 atm, Temperature 298 K, pH 7.0
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | DNA_(5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3') | natural abundance | 1 mM | |
2 | DNA_(5'-D(*GP*GP*AP*CP*TP*TP*GP*CP*TP*AP*GP*C)-3') | natural abundance | 1 mM | |
3 | HNE | natural abundance | 1 mM | |
4 | D2O | natural abundance | 100 % |