BMRB: 18350

cathelicidin-PY

Authors

Yang, J.

Assembly

cathelicidin-PY

Entity

1. cathelicidin-PY (polymer, Thiol state: all disulfide bound), 29 monomers, 3425.122 Da Detail

RKCNFLCKLK EKLRTVITSH IDKVLRPQG

Formula weight

3425.122 Da

Entity Connection

disulfide 1 Detail

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ID	Type	Value order	Atom ID 1	Atom ID 2
1	disulfide	sing	1:CYS3:SG	1:CYS7:SG

Source organism

Lithobates catesbeianus

Exptl. method

solution NMR

Refine. method

distance geometry

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 77.3 %, Completeness (bb): 98.3 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	77.3 % (153 of 198)	77.3 % (153 of 198)
Backbone	98.3 % (57 of 58)	98.3 % (57 of 58)
Sidechain	68.6 % (96 of 140)	68.6 % (96 of 140)
Aromatic	71.4 % (5 of 7)	71.4 % (5 of 7)
Methyl	100.0 % (18 of 18)	100.0 % (18 of 18)

1. entity

RKCNFLCKLK EKLRTVITSH IDKVLRPQG

Show sample condition

Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 298 K, pH 6.2

#	Name	Isotope labeling	Type	Concentration
1	cathelicidin-PY			0.0 ~ 0.0 mM
2	D2O	[U-2H]		10 %
3	H2O	natural abundance		90 %

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Protein Blocks Logo

Calculated from 20 models in PDB: 2LR7, Strand ID: A Detail

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Release date

2012-04-11

Citation

Structure and function of a potent lipopolysaccharide-binding antimicrobial and anti-inflammatory peptide
Wei, L., Yang, J., He, X., Mo, G., Hong, J., Yan, X., Lin, D., Lai, R.
J. Med. Chem. (2013), 56, 3546-3556, PubMed 23594231 , DOI 10.1021/jm4004158 , Abstract

Related entities 1. cathelicidin-PY, : 1 : 4 entities Detail

Experiments performed 2 experiments Detail