Structure of [L-HisB24] insulin analogue at pH 1.9
ID | Type | Value order | Atom ID 1 | Atom ID 2 |
---|---|---|---|---|
1 | disulfide | sing | 1:CYS6:SG | 1:CYS11:SG |
2 | disulfide | sing | 1:CYS7:SG | 2:CYS7:SG |
3 | disulfide | sing | 1:CYS20:SG | 2:CYS19:SG |
Polymer type: polypeptide(L)
Total | 1H | |
---|---|---|
All | 99.0 % (296 of 299) | 99.0 % (296 of 299) |
Backbone | 99.0 % (104 of 105) | 99.0 % (104 of 105) |
Sidechain | 99.0 % (192 of 194) | 99.0 % (192 of 194) |
Aromatic | 96.9 % (31 of 32) | 96.9 % (31 of 32) |
Methyl | 100.0 % (28 of 28) | 100.0 % (28 of 28) |
1. chain A
GIVEQCCTSI CSLYQLENYC N2. chain B
FVNQHLCGSH LVEALYLVCG ERGHFYTPKTSolvent system 95% H2O/5% D2O, Pressure 1 atm, Temperature 298 K, pH 1.9
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | chain_A | natural abundance | 0.250 mM | |
2 | acetic acid | [U-99% 2H] | 20 % | |
3 | chain_B | natural abundance | 0.250 mM | |
4 | H2O | natural abundance | 95 % | |
5 | D2O | natural abundance | 5 % |