Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence
Polymer type: polydeoxyribonucleotide
Total | 1H | |
---|---|---|
All | 90.2 % (184 of 204) | 90.2 % (184 of 204) |
Suger, PO4 | 93.5 % (144 of 154) | 93.5 % (144 of 154) |
Nucleobase | 80.0 % (40 of 50) | 80.0 % (40 of 50) |
Aromatic | 77.3 % (34 of 44) | 77.3 % (34 of 44) |
Methyl | 100.0 % (6 of 6) | 100.0 % (6 of 6) |
1. human telomere quadruplex
AGGGTTAGGG TTAGGGTTAG GGSolvent system 100% D2O, Pressure 1 atm, Temperature 298 K, pH 7
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | human telomere quadruplex | natural abundance | 300 uM | |
2 | LL-(Ru[bipy]2)tppz4+ | natural abundance | 300 uM | |
3 | sodium chloride | natural abundance | 50 mM |