BMRB: 19519

NMR solution structure of the GS-TAMAPIN MUTATION R6A.

Authors

del Rio-Portilla, F., Ramirez-Cordero, B.

Assembly

GS-TAMAPIN MUTATION R6A

Entity

1. GS-TAMAPIN MUTATION R6A (polymer), 33 monomers, 3524.165 Da Detail

GSAFCNLARC ELSCRSLGLL GKCIGEECKC VPY

Formula weight

3524.165 Da

Source organism

Mesobuthus tamulus

Exptl. method

solution NMR

Refine. method

molecular dynamics

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 97.0 %, Completeness: 96.3 %, Completeness (bb): 95.7 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polypeptide(L)

	Total	1H
All	96.3 % (180 of 187)	96.3 % (180 of 187)
Backbone	95.7 % (66 of 69)	95.7 % (66 of 69)
Sidechain	96.6 % (114 of 118)	96.6 % (114 of 118)
Aromatic	88.9 % (8 of 9)	88.9 % (8 of 9)
Methyl	81.3 % (13 of 16)	81.3 % (13 of 16)

1. entity

GSAFCNLARC ELSCRSLGLL GKCIGEECKC VPY

Show sample condition

Sample

Solvent system 95% H2O/5% D2O, Pressure 1 atm, Temperature 273 K, pH 3.4

#	Name	Isotope labeling	Type	Concentration
1	GS-TAMAPIN MUTATION R6A	natural abundance		3 (±0.1) mM
2	H2O	natural abundance		95 %
3	D2O	natural abundance		5 %

Hide sample codition

Protein Blocks Logo

Calculated from 20 models in PDB: 2ME7, Strand ID: A Detail

---

Release date

2014-05-26

Citation

Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines
Ramirez-Cordero, B., Toledano, Y., Cano-Sanchez, P., Hernandez-Lopez, R., Flores-Solis, D., Saucedo-Yanez, A.L., Chavez-Uribe, I., Brieba, L.G., Del Rio-Portilla, F.
Chem. Res. Toxicol. (2014), 27, 960-967, PubMed 24821061 , DOI 10.1021/tx4004193 , Abstract

Related entities 1. GS-TAMAPIN MUTATION R6A, : 1 : 13 : 21 entities Detail

Experiments performed 4 experiments Detail