BMRB: 25106

Structural dynamics of double-helical RNA having CAG motif

Authors

KUMAR, A., TAWANI, A.

Assembly

CAG RNA

Entity

1. CAG RNA (polymer, Thiol state: not present), 9 monomers, 2948.771 × 2 Da Detail

CCGCAGCGG

Total weight

5897.542 Da

Max. entity weight

2948.771 Da

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 33.8 %, Completeness (bb): 16.7 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polyribonucleotide

	Total	1H
All	33.8 % (27 of 80)	33.8 % (27 of 80)
Suger, PO4	16.7 % (9 of 54)	16.7 % (9 of 54)
Nucleobase	69.2 % (18 of 26)	69.2 % (18 of 26)
Aromatic	100.0 % (18 of 18)	100.0 % (18 of 18)

1. RNA (5'-R(P*CP*CP*GP*CP*AP*GP*CP*GP*G)-3')

CCGCAGCGG

Show sample condition

Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 308 K, pH 7.2

#	Name	Isotope labeling	Type	Concentration
1	RNA (5'-R(P*CP*CP*GP*CP*AP*GP*CP*GP*G)-3')	natural abundance		2.35 mM
2	H2O	natural abundance		90 %
3	D2O	natural abundance		10 %
4	Phosphate buffer	natural abundance		10 mM
5	NaCl	natural abundance		100 mM
6	EDTA	natural abundance		0.05 mM

Hide sample codition

Release date

2015-01-25

Citation

Structural Insight reveals dynamics in repeating r(CAG) transcript found in Huntington s disease (HD) and Spinocerebellar ataxias (SCAs)
KUMAR, A., TAWANI, A.
Not known

Experiments performed 3 experiments Detail