BMRB: 25107

Human Telomeric G-quadruplex DNA sequence (TTAGGGT)4 complexed with Flavonoid Quercetin

Authors

KUMAR, A., TAWANI, A.

Assembly

DNA-quercetin

Entity

1. DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3') (polymer, Thiol state: not present), 7 monomers, 2231.417 × 4 Da Detail

TTAGGGT

2. 3,5,7,3',4'-PENTAHYDROXYFLAVONE (non-polymer), 302.236 × 2 Da

Total weight

9530.14 Da

Max. entity weight

2231.417 Da

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 86.4 %, Completeness (bb): 87.8 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polydeoxyribonucleotide

	Total	1H
All	86.4 % (57 of 66)	86.4 % (57 of 66)
Suger, PO4	87.8 % (43 of 49)	87.8 % (43 of 49)
Nucleobase	82.4 % (14 of 17)	82.4 % (14 of 17)
Aromatic	78.6 % (11 of 14)	78.6 % (11 of 14)
Methyl	100.0 % (3 of 3)	100.0 % (3 of 3)

1. DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3')

TTAGGGT

Show sample condition

Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 298 K, pH 7.2

#	Name	Isotope labeling	Type	Concentration
1	DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3')	natural abundance		2.25 mM
2	D2O	natural abundance		10 %
3	H2O	natural abundance		90 %

Hide sample codition

Release date

2015-01-25

Citation

Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes
KUMAR, A., TAWANI, A.
J. Biol. Chem. (2012), 287, 24122-24130, PubMed 22621930 , DOI 10.1074/jbc.M112.343608 , Abstract

Experiments performed 3 experiments Detail