Search

NMR resolved structure of VG16KRKP, an antimicrobial peptide in D8PG micelles
Authors
Bhunia, A., Datta, A.
Assembly
VG16KRKP, an antimicrobial peptide in D8PG micelles
Entity
1. VG16KRKP, an antimicrobial peptide in D8PG micelles (polymer, Thiol state: all free), 16 monomers, 1760.116 Da Detail

VARGWKRKCP LFGKGG


Formula weight
1760.116 Da
Exptl. method
solution NMR
Refine. method
torsion angle dynamics
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 100.0 %, Completeness: 81.0 %, Completeness (bb): 97.1 % Detail

Polymer type: polypeptide(L)

Total1H
All81.0 % (85 of 105)81.0 % (85 of 105)
Backbone97.1 % (34 of 35)97.1 % (34 of 35)
Sidechain72.9 % (51 of 70)72.9 % (51 of 70)
Aromatic36.4 % (4 of 11)36.4 % (4 of 11)
Methyl100.0 % (5 of 5)100.0 % (5 of 5)

1. antimicrobial peptide

VARGWKRKCP LFGKGG

Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 298 K, pH 4.5


#NameIsotope labelingTypeConcentration
1antimicrobial peptidenatural abundance0.5 mM
2H2Onatural abundance90 %
3Dioctanoyl phosphatidyl glycerolnatural abundance10 mM
4D2Onatural abundance10 %

Protein Blocks Logo
Calculated from 20 models in PDB: 2MXG, Strand ID: A Detail


Release date
2015-02-01
Citation
De-novo design of antimicrobial peptides:insights into membrane permeabilisation, lipopolysachharide fragmentation and application in plant disease control
Bhunia, A., Datta, A.
Not known
Related entities 1. VG16KRKP, an antimicrobial peptide in D8PG micelles, : 1 : 9 : 3 : 106 entities Detail
Experiments performed 2 experiments Detail
NMR combined restraints 4 contents Detail
Keywords peptide, turn