BMRB: 25737

The NMR solution structure of octyl-tridecaptin A1 in DPC micelles

Authors

Cochrane, S.A., Findlay, B., Bakhtiary, A., Rodriguez-Lopez, E.M., Vederas, J.C.

Assembly

octyl-tridecaptin A1

Entity

1. octyl-tridecaptin A1 (polymer, Thiol state: not present), 13 monomers, 1394.573 Da Detail

XXGXXSXXFE VXA

Formula weight

1394.573 Da

Source organism

Paenibacillus terrae

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 46.2 %, Completeness: 100.0 %, Completeness (bb): 100.0 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	100.0 % (30 of 30)	100.0 % (30 of 30)
Backbone	100.0 % (13 of 13)	100.0 % (13 of 13)
Sidechain	100.0 % (17 of 17)	100.0 % (17 of 17)
Aromatic	100.0 % (5 of 5)	100.0 % (5 of 5)
Methyl	100.0 % (3 of 3)	100.0 % (3 of 3)

1. entity

XXGXXSXXFE VXA

Show sample condition

Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 273 K, pH 6

#	Name	Isotope labeling	Type	Concentration
1	entity	natural abundance		0.0 ~ 0.0 mM
2	D2O	natural abundance		10 %
3	H2O	natural abundance		90 %
4	DPC	natural abundance		180 mM

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Release date

2016-09-21

Citation

Antimicrobial lipopeptide tridecaptin A1 selectively binds to Gram-negative lipid II
Cochrane, S.A., Findlay, B., Bakhtiary, A., Acedo, J.Z., Rodriguez-Lopez, E.M., Mercier, P., Vederas, J.C.
Proc. Natl. Acad. Sci. U. S. A. (2016), 113, 11561-11566, PubMed 27688760 , DOI 10.1073/pnas.1608623113 , Abstract

Experiments performed 2 experiments Detail