Solution NMR structure of spider toxin analogue [E17K]ProTx-II
ID | Type | Value order | Atom ID 1 | Atom ID 2 |
---|---|---|---|---|
1 | disulfide | sing | 1:CYS2:SG | 1:CYS16:SG |
2 | disulfide | sing | 1:CYS9:SG | 1:CYS21:SG |
3 | disulfide | sing | 1:CYS15:SG | 1:CYS25:SG |
Polymer type: polypeptide(L)
Total | 1H | 13C | 15N | |
---|---|---|---|---|
All | 79.8 % (317 of 397) | 93.9 % (199 of 212) | 60.0 % (90 of 150) | 80.0 % (28 of 35) |
Backbone | 82.8 % (149 of 180) | 98.4 % (60 of 61) | 68.5 % (61 of 89) | 93.3 % (28 of 30) |
Sidechain | 80.1 % (197 of 246) | 92.1 % (139 of 151) | 64.4 % (58 of 90) | 0.0 % (0 of 5) |
Aromatic | 50.0 % (28 of 56) | 100.0 % (28 of 28) | 0.0 % (0 of 24) | 0.0 % (0 of 4) |
Methyl | 85.7 % (12 of 14) | 85.7 % (6 of 7) | 85.7 % (6 of 7) |
1. entity 1
YCQKWMWTCD SERKCCKGMV CRLWCKKKLWSolvent system 90% H2O/10% D2O, Pressure 1 Pa, Temperature 298 K, pH 3.5 (±0.5), Details 2 mg/mL [E17K]ProTx-II, 90% H2O/10% D2O
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | [E17K]ProTx-II | natural abundance | 2 mg/mL |