Solution structure of the major MYC promoter G-quadruplex with a wild-type flanking in complex with NSC85697, a quinoline derivative
Polymer type: polydeoxyribonucleotide
Total | 1H | |
---|---|---|
All | 96.0 % (194 of 202) | 96.0 % (194 of 202) |
Suger, PO4 | 98.7 % (152 of 154) | 98.7 % (152 of 154) |
Nucleobase | 87.5 % (42 of 48) | 87.5 % (42 of 48) |
Aromatic | 86.4 % (38 of 44) | 86.4 % (38 of 44) |
Methyl | 100.0 % (4 of 4) | 100.0 % (4 of 4) |
1. entity 1
TGAGGGTGGG TAGGGTGGGG AASolvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 298 K, pH 7, Details 0.8 mM Myc2345, 2.4 mM NSC85697, 10 mM potassium phosphate, 90% H2O/10% D2O
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | Myc2345 | natural abundance | 0.8 mM | |
2 | NSC85697 | natural abundance | 2.4 mM | |
3 | potassium phosphate | natural abundance | 10 mM |