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BMRB: 31075


31075
8ZX6
Temperature-dependent structures of tau aggregates
Authors
El Mammeri, N., Duan, P., Dregni, A.J., Hong, M.
Assembly
Microtubule-associated protein tau
Entity
1. Microtubule-associated protein tau (polymer), 202 monomers, 21409.27 × 10 Da Detail

SSPGSPGTPG SRSRTPSLPT PPTREPKKVA VVRTPPKSPS SAKSRLQTAP VPMPDLKNVK SKIGSTENLK HQPGGGKVQI INKKLDLSNV QSKCGSKDNI KHVPGGGSVQ IVYKPVDLSK VTSKCGSLGN IHHKPGGGQV EVKSEKLDFK DRVQSKIGSL DNITHVPGGG NKKIETHKLT FRENAKAKTD HGAEIVYKSP VV


Total weight
214092.69 Da
Max. entity weight
21409.27 Da
Source organism
Homo sapiens
Exptl. method
solid-state NMR
Data set
assigned_chemical_shifts
Chemcal Shifts
13C: 259, 15N: 70 assignments Detail
Download
IDEntity IDSeq IDComp IDAtom IDAtom typeValVal errAmbig. code
1179GLNCGC32.833
2180ILECC171.645
3180ILECAC58.752
4180ILECBC37.934
5180ILECG1C25.644
6180ILECG2C15.886
7180ILECD1C11.293
8180ILENN125.816
9181ILECC171.739
10181ILECAC57.294
11181ILECBC39.611
12181ILECG1C25.056
13181ILECG2C14.853
14181ILECD1C11.064
15181ILENN126.454
16182ASNCC171.758
17182ASNCAC50.014
18182ASNCBC38.853
19182ASNCGC173.586
20182ASNNN126.034
21182ASNND2N107.4
22183LYSCAC52.062
23183LYSNN122.694
24184LYSCC172.929
25184LYSCAC52.478
26184LYSCBC33.164
27184LYSCGC25.248
28184LYSCDC29.009
29184LYSCEC43.97
30184LYSNN127.14
31186ASPCC171.523
32186ASPCAC51.534
33186ASPCBC40.636
34186ASPCGC178.669
35186ASPNN125.8
36187LEUCC174.969
37187LEUCAC52.385
38187LEUCBC41.332
39187LEUCGC27.104
40187LEUCD1C24.182
41187LEUNN125.039
42188SERCC170.883
43188SERCAC54.816
44188SERCBC62.647
45188SERNN118.264
46189ASNCAC50.768
47189ASNCBC42.769
48189ASNCGC172.18
49189ASNNN126.771
50190VALCC173.693
51190VALCAC59.51
52190VALCBC33.008
53190VALCG1C19.282
54190VALNN130.61
55191GLNCC173.029
56191GLNCAC51.648
57191GLNCBC33.989
58191GLNCGC35.746
59191GLNCDC179.14
60191GLNNN121.347
61191GLNNE2N115.858
62192SERCC173.165
63192SERCAC52.873
64192SERCBC63.11
65192SERNN115.281
66193LYSCC173.955
67193LYSCAC56.338
68193LYSCGC25.409
69193LYSCDC27.993
70193LYSCEC41.037
71193LYSNN125.09
72194CYSCC172.854
73194CYSCAC55.523
74194CYSCBC25.975
75194CYSNN116.575
76195GLYCC171.687
77195GLYCAC43.151
78195GLYNN112.591
79196SERCC172.836
80196SERCAC54.892
81196SERCBC65.717
82196SERNN115.759
83197LYSCC172.699
84197LYSCAC52.628
85197LYSCBC35.243
86197LYSCGC22.83
87197LYSCDC29.413
88197LYSNN132.918
89198ASPCC173.15
90198ASPCAC51.735
91198ASPCBC37.337
92198ASPCGC180.5
93198ASPNN122.017
94199ASNCC175.103
95199ASNCAC49.827
96199ASNCBC41.367
97199ASNNN113.303
981100ILECAC58.492
991100ILECBC39.112
1001100ILECG1C26.075
1011100ILECG2C15.712
1021100ILECD1C11.978
1031100ILENN121.834
1041101LYSCC171.027
1051101LYSCAC52.617
1061102HISCC172.514
1071102HISCAC51.381
1081102HISCBC32.39
1091102HISCD2C114.795
1101102HISCE1C135.406
1111102HISNN130.425
1121103VALCC169.203
1131103VALCAC56.697
1141103VALCBC31.097
1151103VALCG1C17.865
1161103VALCG2C20.352
1171103VALNN127.903
1181104PROCC175.596
1191104PROCAC59.564
1201104PROCBC32.446
1211104PROCGC25.622
1221104PROCDC45.635
1231104PRONN133.384
1241105GLYCC171.35
1251105GLYCAC42.965
1261105GLYNN105.909
1271106GLYCC172.657
1281106GLYCAC43.073
1291106GLYNN115.797
1301107GLYCC172.499
1311107GLYCAC46.874
1321107GLYNN105.801
1331108SERCC169.768
1341108SERCAC56.467
1351108SERCBC67.429
1361108SERNN107.454
1371109VALCC172.64
1381109VALCAC59.492
1391109VALCBC31.958
1401109VALCG1C20.872
1411109VALCG2C18.174
1421109VALNN121.924
1431110GLNCC172.459
1441110GLNCAC51.807
1451110GLNCBC30.057
1461110GLNCGC31.783
1471110GLNCDC177.327
1481110GLNNN126.292
1491110GLNNE2N111.681
1501111ILECC172.091
1511111ILECAC57.552
1521111ILECBC39.923
1531111ILECG1C25.319
1541111ILECG2C14.755
1551111ILECD1C13.078
1561111ILENN124.471
1571112VALCC172.01
1581112VALCAC58.774
1591112VALCBC32.037
1601112VALCG1C18.662
1611112VALCG2C19.584
1621112VALNN127.43
1631113TYRCC169.975
1641113TYRCAC55.809
1651113TYRCBC40.525
1661113TYRNN130.09
1671115PROCC174.928
1681115PROCAC60.596
1691115PROCBC30.606
1701115PROCGC25.739
1711115PROCDC47.086
1721115PRONN131.521
1731116VALCC173.104
1741116VALCAC59.814
1751116VALCBC32.792
1761116VALCG1C19.53
1771116VALNN121.682
1781117ASPCC171.858
1791117ASPCAC50.961
1801117ASPCBC39.752
1811117ASPCGC178.249
1821117ASPNN128.418
1831118LEUCC174.971
1841118LEUCAC52.406
1851118LEUCBC41.244
1861118LEUCGC26.573
1871118LEUCD1C24.599
1881118LEUNN129.798
1891119SERCC171.397
1901119SERCAC57.796
1911119SERCBC63.955
1921119SERNN119.192
1931120LYSCC174.71
1941120LYSCAC53.563
1951120LYSCBC34.542
1961120LYSCGC23.761
1971120LYSNN118.163
1981121VALCC173.052
1991121VALCAC59.807
2001121VALCBC34.341
2011121VALCG1C20.831
2021121VALCG2C19.676
2031121VALNN126.266
2041122THRCC171.087
2051122THRCAC60.223
2061122THRCBC67.668
2071122THRCG2C21.161
2081122THRNN128.396
2091123SERCC172.579
2101123SERCAC53.08
2111123SERCBC62.603
2121123SERNN119.676
2131124LYSCC172.757
2141124LYSCAC55.831
2151124LYSCGC25.672
2161124LYSCDC28.203
2171124LYSCEC40.624
2181124LYSNN127.63
2191125CYSCC172.579
2201125CYSCAC55.661
2211125CYSCBC29.349
2221125CYSNN109.755
2231126GLYCAC43.157
2241126GLYNN109.993
2251127SERCAC53.745
2261127SERCBC61.951
2271127SERNN121.751
2281132HISCC171.312
2291132HISCAC53.017
2301132HISCBC33.177
2311132HISCD2C114.657
2321132HISCE1C134.415
2331132HISNN126.468
2341133HISCC170.615
2351133HISCAC54.85
2361133HISCBC29.771
2371133HISCD2C114.139
2381133HISCE1C132.203
2391133HISNN126.386
2401134LYSCC173.087
2411134LYSCAC52.602
2421134LYSCBC31.039
2431134LYSCGC23.905
2441134LYSCDC28.661
2451134LYSNN126.423
2461158GLYCC172.8
2471158GLYCAC46.259
2481158GLYNN119.144
2491159SERCC169.267
2501159SERCAC56.825
2511159SERCBC66.356
2521159SERNN111.365
2531164THRCC171.314
2541164THRCAC54.681
2551164THRCBC64.461
2561164THRNN117.933
2571165HISCC172.025
2581165HISCAC53.107
2591165HISCBC33.183
2601165HISCGC134.97
2611165HISCD2C114.554
2621165HISCE1C135.843
2631165HISNN123.797
2641170GLYCC172.227
2651170GLYCAC45.757
2661170GLYNN106.945
2671171ASNCAC51.188
2681171ASNCBC40.099
2691171ASNNN117.029
2701175GLUCC174.186
2711175GLUCAC51.814
2721175GLUCBC29.264
2731175GLUCGC35.812
2741175GLUCDC181.675
2751175GLUNN123.093
2761176THRCC174.257
2771176THRCAC59.601
2781176THRCBC66.186
2791176THRCG2C21.498
2801176THRNN113.907
2811177HISCC171.584
2821177HISCAC53.443
2831177HISCBC34.63
2841177HISCD2C113.796
2851177HISCE1C134.765
2861177HISNN125.721
2871178LYSCAC52.269
2881178LYSCBC29.148
2891178LYSCGC21.855
2901178LYSCDC25.333
2911178LYSCEC44.057
2921178LYSNN126.043
2931185ALACC173.006
2941185ALACAC48.654
2951185ALACBC20.786
2961185ALANN128.749
2971186LYSCC172.364
2981186LYSCAC53.08
2991186LYSCBC32.179
3001186LYSNN118.358
3011187ALACC173.198
3021187ALACAC48.714
3031187ALACBC20.673
3041187ALANN127.074
3051188LYSCC174.91
3061188LYSCAC53.63
3071188LYSCBC31.227
3081188LYSNN119.634
3091189THRCC172.605
3101189THRCAC57.703
3111189THRCBC67.055
3121189THRCG2C19.744
3131189THRNN108.507
3141191HISCAC50.481
3151191HISCBC29.717
3161191HISCGC127.2
3171191HISCE1C135.106
3181191HISNN128.229
3191192GLYCC170.969
3201192GLYCAC44.943
3211192GLYNN108.718
3221193ALACC174.544
3231193ALACAC49.537
3241193ALACBC18.01
3251193ALANN121.808
3261194GLUCAC53.637
3271194GLUCBC31.744
3281194GLUCGC34.681
3291194GLUNN121.829

Release date
2023-02-22
Citation
Influence of Fibril Growth Rates on the Structure of Tau Aggregates
El Mammeri, N., Duan, P., Dregni, A.J., Hong, M.
Related entities 1. Microtubule-associated protein tau, : 1 : 104 : 3 : 2 : 21 entities Detail
More details for 131 related entities
Interaction partners 1. Microtubule-associated protein tau, : 50 interactors Detail
More details for 50 interactors identified by 27 citations
Experiments performed 5 experiments Detail
Chemical shift validation 3 contents Detail
Keywords PROTEIN FIBRIL, amyloid fibril, tau