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Open State of the SARS-CoV-2 Envelope Protein Transmembrane Domain, Determined by Solid-State NMR
Authors
Medeiros-Silva, J., Dregni, A.J., Somberg, N.H., Hong, M.
Assembly
Envelope small membrane protein
Entity
1. Envelope small membrane protein (polymer, Thiol state: not present), 31 monomers, 3361.105 × 5 Da Detail

ETGTLIVNSV LLFLAFVVFL LVTLAILTAL R


Total weight
16805.525 Da
Max. entity weight
3361.105 Da
Source organism
Severe acute respiratory syndrome coronavirus 2
Exptl. method
solid-state NMR
Data set
assigned_chemical_shifts
Chemcal Shifts
1H: 32, 13C: 146, 15N: 34 assignments Detail
IDEntity IDSeq IDComp IDAtom IDAtom typeValVal errAmbig. code
111GLUCC170.800.251
211GLUCAC53.800.251
311GLUCBC27.060.251
411GLUCGC33.600.251
511GLUCDC178.000.251
612THRHH8.860.031
712THRCAC61.500.251
812THRCBC67.200.251
912THRNN117.700.101
1013GLYHH8.820.031
1113GLYCC172.500.251
1213GLYCAC44.800.251
1313GLYNN111.400.101
1414THRHH8.190.031
1514THRCC173.400.251
1614THRCAC62.500.251
1714THRCBC66.500.251
1814THRCG2C20.400.251
1914THRNN113.900.101
2015LEUCAC55.700.251
2115LEUCBC39.500.251
2215LEUCGC25.000.251
2315LEUNN121.900.101
2416ILEHH8.140.031
2516ILECC175.100.251
2616ILECAC62.100.251
2716ILECBC35.300.251
2816ILECG1C27.100.251
2916ILECG2C15.900.251
3016ILECD1C10.900.251
3116ILENN120.400.101
3217VALHH8.110.031
3317VALCC174.700.251
3417VALCAC64.900.251
3517VALCBC29.200.251
3617VALCG1C21.300.251
3717VALCG2C18.800.251
3817VALNN117.100.101
3918ASNHH8.110.031
4018ASNHD21H7.500.031
4118ASNHD22H6.700.031
4218ASNCC175.400.251
4318ASNCAC53.900.251
4418ASNCBC35.400.251
4518ASNCGC172.200.251
4618ASNNN117.100.101
4718ASNND2N107.700.101
4819SERHH8.250.031
4919SERCC173.200.251
5019SERCAC60.900.251
5119SERCBC61.000.251
5219SERNN116.400.101
53110VALHH8.130.031
54110VALCC175.400.251
55110VALCAC64.700.251
56110VALCBC29.200.251
57110VALCG1C21.300.251
58110VALCG2C19.400.251
59110VALNN121.000.101
60111LEUHH8.510.031
61111LEUCC176.700.251
62111LEUCAC55.600.251
63111LEUCBC39.000.251
64111LEUCGC24.700.251
65111LEUCD1C23.400.251
66111LEUCD2C18.300.251
67111LEUNN118.700.101
68112LEUHH8.480.031
69112LEUCC176.000.251
70112LEUCAC56.100.251
71112LEUCBC39.900.251
72112LEUCGC24.900.251
73112LEUNN120.200.101
74113PHEHH8.260.031
75113PHECC174.500.251
76113PHECAC59.500.251
77113PHECBC37.400.251
78113PHECGC136.800.251
79113PHECD1C129.300.251
80113PHECE1C128.300.251
81113PHENN118.700.101
82114LEUHH9.070.031
83114LEUCC176.600.251
84114LEUCAC55.500.251
85114LEUCBC40.800.251
86114LEUCGC24.900.251
87114LEUCD1C23.600.251
88114LEUCD2C20.200.251
89114LEUNN118.600.101
90115ALAHH9.330.031
91115ALACC176.500.251
92115ALACAC53.900.251
93115ALACBC16.500.251
94115ALANN123.400.101
95116PHEHH8.330.031
96116PHECC174.300.251
97116PHECAC59.400.251
98116PHECBC37.300.251
99116PHECGC137.200.251
100116PHECD1C129.300.251
101116PHECE1C127.300.251
102116PHENN118.800.101
103117VALHH8.560.031
104117VALCC175.700.251
105117VALCAC65.400.251
106117VALCBC29.700.251
107117VALCG1C21.000.251
108117VALCG2C18.800.251
109117VALNN118.000.101
110118VALHH9.360.031
111118VALCC174.800.251
112118VALCAC65.600.251
113118VALCBC29.100.251
114118VALCG1C21.100.251
115118VALCG2C19.500.251
116118VALNN118.800.101
117119PHEHH8.790.031
118119PHECC175.700.251
119119PHECAC60.200.251
120119PHECBC37.000.251
121119PHECGC137.000.251
122119PHECD1C129.300.251
123119PHECE1C128.100.251
124119PHENN119.600.101
125120LEUHH8.170.031
126120LEUCC175.900.251
127120LEUCAC55.600.251
128120LEUCBC39.800.251
129120LEUCGC25.500.251
130120LEUCD1C23.800.251
131120LEUCD2C18.600.251
132120LEUNN120.600.101
133121LEUHH8.410.031
134121LEUCC176.600.251
135121LEUCAC55.500.251
136121LEUCBC39.100.251
137121LEUCGC23.500.251
138121LEUCD1C23.400.251
139121LEUCD2C18.800.251
140121LEUNN118.700.101
141122VALHH8.950.031
142122VALCC175.000.251
143122VALCAC64.300.251
144122VALCBC28.700.251
145122VALCG1C22.200.251
146122VALCG2C19.400.251
147122VALNN119.500.101
148123THRHH7.710.031
149123THRCC173.500.251
150123THRCAC66.900.251
151123THRCBC64.400.251
152123THRCG2C18.200.251
153123THRNN119.100.101
154124LEUHH7.910.031
155124LEUCC176.100.251
156124LEUCAC56.500.251
157124LEUCBC39.500.251
158124LEUCGC25.300.251
159124LEUCD1C25.200.251
160124LEUCD2C22.300.251
161124LEUNN121.600.101
162125ALAHH8.400.031
163125ALACC177.000.251
164125ALACAC53.500.251
165125ALACBC16.500.251
166125ALANN123.600.101
167126ILEHH8.590.031
168126ILECC175.000.251
169126ILECAC63.600.251
170126ILECBC36.100.251
171126ILECG1C28.900.251
172126ILECG2C17.100.251
173126ILECD1C12.200.251
174126ILENN117.500.101
175127LEUHH8.410.031
176127LEUCC176.500.251
177127LEUCAC55.900.251
178127LEUCBC38.800.251
179127LEUCGC25.600.251
180127LEUCD1C25.500.251
181127LEUCD2C21.500.251
182127LEUNN116.700.101
183128THRHH7.690.031
184128THRCC173.600.251
185128THRCAC60.900.251
186128THRCBC67.400.251
187128THRCG2C19.800.251
188128THRNN102.600.101
189129ALAHH7.410.031
190129ALACC177.000.251
191129ALACAC51.600.251
192129ALACBC17.600.251
193129ALANN123.100.101
194130LEUHH7.310.031
195130LEUCC171.000.251
196130LEUCAC51.300.251
197130LEUCBC36.600.251
198130LEUCGC24.400.251
199130LEUCD1C23.300.251
200130LEUCD2C19.900.251
201130LEUNN118.700.101
202131ARGHH7.100.031
203131ARGHEH7.200.031
204131ARGCAC51.500.251
205131ARGCBC27.900.251
206131ARGCGC23.500.251
207131ARGCDC39.600.251
208131ARGCZC157.300.251
209131ARGNN124.000.101
210131ARGNEN85.800.101
211131ARGNH1N70.000.101
212131ARGNH2N75.800.101

Release date
2023-06-13
Related entities 1. Envelope small membrane protein, : 1 : 4 : 1 : 7 entities Detail
Experiments performed 9 experiments Detail
Chemical shift validation 3 contents Detail
Keywords Cation Channel, SARS-CoV-2, VIRAL PROTEIN, Viroporin