BMRB: 34831

Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine

Authors

Borggraefe, J., Gaussmann, S., Sattler, M.

Assembly

Survival of motor neuron-related-splicing factor 30

Entity

1. Survival of motor neuron-related-splicing factor 30, entity 1 (polymer), 64 monomers, 6931.477 Da Detail

ASTQPTHSWK VGDKCMAVWS EDGQCYEAEI EEIDEENGTA AITFAGYGNA EVTPLLNLKP VEEG

2. Survival of motor neuron-related-splicing factor 30, entity 2 (non-polymer), 177.226 Da

Total weight

7108.703 Da

Max. entity weight

6931.477 Da

Source organism

Homo sapiens

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chemcal Shifts

¹H: 322, ¹³C: 198 assignments Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

ID	Entity ID	Seq ID	Comp ID	Atom ID	Atom type	Val	Val err	Ambig. code
1	1	1	ALA	HA	H	4.271	0.020	1
2	1	1	ALA	HB1	H	1.331	0.020	1
3	1	1	ALA	HB2	H	1.331	0.020	1
4	1	1	ALA	HB3	H	1.331	0.020	1
5	1	1	ALA	CA	C	52.413	0.3	1
6	1	1	ALA	CB	C	19.186	0.3	1
7	1	2	SER	HA	H	4.419	0.020	1
8	1	2	SER	HB2	H	3.782	0.020	2
9	1	2	SER	HB3	H	3.834	0.020	2
10	1	2	SER	CA	C	58.085	0.3	1
11	1	2	SER	CB	C	63.628	0.3	1
12	1	3	THR	HA	H	4.283	0.020	1
13	1	3	THR	HB	H	4.157	0.020	1
14	1	3	THR	HG21	H	1.117	0.020	1
15	1	3	THR	HG22	H	1.117	0.020	1
16	1	3	THR	HG23	H	1.117	0.020	1
17	1	3	THR	CA	C	61.589	0.3	1
18	1	3	THR	CB	C	69.597	0.3	1
19	1	3	THR	CG2	C	21.568	0.3	1
20	1	4	GLN	HA	H	4.568	0.020	1
21	1	4	GLN	HB2	H	1.854	0.020	2
22	1	4	GLN	HB3	H	2.019	0.020	2
23	1	4	GLN	HG3	H	2.306	0.020	1
24	1	4	GLN	CA	C	53.517	0.3	1
25	1	4	GLN	CB	C	28.920	0.3	1
26	1	4	GLN	CG	C	33.294	0.3	1
27	1	5	PRO	HA	H	4.414	0.020	1
28	1	5	PRO	HB2	H	1.804	0.020	2
29	1	5	PRO	HB3	H	2.204	0.020	2
30	1	5	PRO	HG3	H	1.931	0.020	1
31	1	5	PRO	HD2	H	3.592	0.020	2
32	1	5	PRO	HD3	H	3.733	0.020	2
33	1	5	PRO	CA	C	62.981	0.3	1
34	1	5	PRO	CB	C	32.089	0.3	1
35	1	5	PRO	CG	C	27.366	0.3	1
36	1	5	PRO	CD	C	50.620	0.3	1
37	1	6	THR	HA	H	4.164	0.020	1
38	1	6	THR	HB	H	4.076	0.020	1
39	1	6	THR	HG21	H	1.105	0.020	1
40	1	6	THR	HG22	H	1.105	0.020	1
41	1	6	THR	HG23	H	1.105	0.020	1
42	1	6	THR	CA	C	61.751	0.3	1
43	1	6	THR	CB	C	69.625	0.3	1
44	1	6	THR	CG2	C	21.539	0.3	1
45	1	7	HIS	HA	H	4.341	0.020	1
46	1	7	HIS	HB2	H	2.577	0.020	2
47	1	7	HIS	HB3	H	2.805	0.020	2
48	1	7	HIS	HD2	H	6.068	0.020	1
49	1	7	HIS	HE1	H	7.818	0.020	1
50	1	7	HIS	CA	C	55.391	0.3	1
51	1	7	HIS	CB	C	30.649	0.3	1
52	1	7	HIS	CD2	C	119.188	0.3	1
53	1	7	HIS	CE1	C	137.021	0.3	1
54	1	8	SER	HA	H	4.349	0.020	1
55	1	8	SER	HB2	H	3.499	0.020	2
56	1	8	SER	HB3	H	3.584	0.020	2
57	1	8	SER	CA	C	56.938	0.3	1
58	1	8	SER	CB	C	63.157	0.3	1
59	1	9	TRP	HA	H	4.732	0.020	1
60	1	9	TRP	HB2	H	2.845	0.020	2
61	1	9	TRP	HB3	H	2.996	0.020	2
62	1	9	TRP	HD1	H	7.119	0.020	1
63	1	9	TRP	HE3	H	8.008	0.020	1
64	1	9	TRP	HZ2	H	6.792	0.020	1
65	1	9	TRP	HZ3	H	7.168	0.020	1
66	1	9	TRP	HH2	H	6.626	0.020	1
67	1	9	TRP	CA	C	56.727	0.3	1
68	1	9	TRP	CB	C	32.151	0.3	1
69	1	9	TRP	CD1	C	127.302	0.3	1
70	1	9	TRP	CE3	C	122.315	0.3	1
71	1	9	TRP	CZ2	C	113.657	0.3	1
72	1	9	TRP	CZ3	C	121.132	0.3	1
73	1	9	TRP	CH2	C	123.498	0.3	1
74	1	10	LYS	HA	H	4.558	0.020	1
75	1	10	LYS	HB2	H	1.678	0.020	2
76	1	10	LYS	HB3	H	1.732	0.020	2
77	1	10	LYS	HG2	H	1.267	0.020	2
78	1	10	LYS	HG3	H	1.470	0.020	2
79	1	10	LYS	HD2	H	1.627	0.020	1
80	1	10	LYS	HE3	H	2.936	0.020	1
81	1	10	LYS	CA	C	54.206	0.3	1
82	1	10	LYS	CB	C	35.759	0.3	1
83	1	10	LYS	CG	C	23.666	0.3	1
84	1	10	LYS	CD	C	29.067	0.3	1
85	1	10	LYS	CE	C	41.899	0.3	1
86	1	11	VAL	HA	H	3.167	0.020	1
87	1	11	VAL	HB	H	1.820	0.020	1
88	1	11	VAL	HG11	H	0.852	0.020	2
89	1	11	VAL	HG12	H	0.852	0.020	2
90	1	11	VAL	HG13	H	0.852	0.020	2
91	1	11	VAL	HG21	H	0.921	0.020	2
92	1	11	VAL	HG22	H	0.921	0.020	2
93	1	11	VAL	HG23	H	0.921	0.020	2
94	1	11	VAL	CA	C	65.756	0.3	1
95	1	11	VAL	CB	C	31.330	0.3	1
96	1	11	VAL	CG1	C	21.432	0.3	1
97	1	11	VAL	CG2	C	22.998	0.3	1
98	1	12	GLY	HA2	H	3.661	0.020	2
99	1	12	GLY	HA3	H	4.389	0.020	2
100	1	12	GLY	CA	C	44.342	0.3	1
101	1	13	ASP	HA	H	4.611	0.020	1
102	1	13	ASP	HB2	H	2.948	0.020	2
103	1	13	ASP	HB3	H	3.191	0.020	2
104	1	13	ASP	CA	C	55.450	0.3	1
105	1	13	ASP	CB	C	41.602	0.3	1
106	1	14	LYS	HA	H	5.048	0.020	1
107	1	14	LYS	HB3	H	1.813	0.020	1
108	1	14	LYS	HG2	H	1.534	0.020	2
109	1	14	LYS	HG3	H	1.594	0.020	2
110	1	14	LYS	HD3	H	1.648	0.020	1
111	1	14	LYS	CA	C	54.459	0.3	1
112	1	14	LYS	CB	C	33.631	0.3	1
113	1	14	LYS	CG	C	25.181	0.3	1
114	1	14	LYS	CD	C	28.566	0.3	1
115	1	15	CYS	HA	H	5.024	0.020	1
116	1	15	CYS	HB2	H	2.266	0.020	2
117	1	15	CYS	HB3	H	2.571	0.020	2
118	1	15	CYS	CA	C	55.357	0.3	1
119	1	15	CYS	CB	C	32.054	0.3	1
120	1	16	MET	HA	H	5.227	0.020	1
121	1	16	MET	HB2	H	1.628	0.020	2
122	1	16	MET	HB3	H	1.763	0.020	2
123	1	16	MET	HG2	H	2.487	0.020	2
124	1	16	MET	HG3	H	2.541	0.020	2
125	1	16	MET	CA	C	53.107	0.3	1
126	1	16	MET	CB	C	32.899	0.3	1
127	1	16	MET	CG	C	31.885	0.3	1
128	1	17	ALA	HA	H	4.858	0.020	1
129	1	17	ALA	HB1	H	1.072	0.020	1
130	1	17	ALA	HB2	H	1.072	0.020	1
131	1	17	ALA	HB3	H	1.072	0.020	1
132	1	17	ALA	CA	C	50.263	0.3	1
133	1	17	ALA	CB	C	23.679	0.3	1
134	1	18	VAL	HA	H	4.229	0.020	1
135	1	18	VAL	HB	H	1.848	0.020	1
136	1	18	VAL	HG11	H	0.621	0.020	2
137	1	18	VAL	HG12	H	0.621	0.020	2
138	1	18	VAL	HG13	H	0.621	0.020	2
139	1	18	VAL	HG21	H	0.870	0.020	2
140	1	18	VAL	HG22	H	0.870	0.020	2
141	1	18	VAL	HG23	H	0.870	0.020	2
142	1	18	VAL	CA	C	62.325	0.3	1
143	1	18	VAL	CB	C	32.661	0.3	1
144	1	18	VAL	CG1	C	21.002	0.3	1
145	1	18	VAL	CG2	C	22.374	0.3	1
146	1	19	TRP	HA	H	5.196	0.020	1
147	1	19	TRP	HB3	H	3.665	0.020	1
148	1	19	TRP	HD1	H	7.077	0.020	1
149	1	19	TRP	HE3	H	7.507	0.020	1
150	1	19	TRP	HZ2	H	6.788	0.020	1
151	1	19	TRP	HZ3	H	6.256	0.020	1
152	1	19	TRP	HH2	H	6.626	0.020	1
153	1	19	TRP	CA	C	54.322	0.3	1
154	1	19	TRP	CB	C	29.804	0.3	1
155	1	19	TRP	CD1	C	125.315	0.3	1
156	1	19	TRP	CE3	C	123.836	0.3	1
157	1	19	TRP	CZ2	C	114.286	0.3	1
158	1	19	TRP	CZ3	C	121.565	0.3	1
159	1	19	TRP	CH2	C	124.724	0.3	1
160	1	20	SER	HA	H	3.817	0.020	1
161	1	20	SER	HB2	H	3.646	0.020	2
162	1	20	SER	HB3	H	3.808	0.020	2
163	1	20	SER	CA	C	61.080	0.3	1
164	1	20	SER	CB	C	62.255	0.3	1
165	1	21	GLU	HA	H	3.494	0.020	1
166	1	21	GLU	HB2	H	-0.092	0.020	2
167	1	21	GLU	HB3	H	0.363	0.020	2
168	1	21	GLU	HG2	H	1.436	0.020	2
169	1	21	GLU	HG3	H	1.543	0.020	2
170	1	21	GLU	CA	C	57.969	0.3	1
171	1	21	GLU	CB	C	27.828	0.3	1
172	1	21	GLU	CG	C	35.762	0.3	1
173	1	22	ASP	HA	H	4.615	0.020	1
174	1	22	ASP	HB2	H	2.248	0.020	2
175	1	22	ASP	HB3	H	2.951	0.020	2
176	1	22	ASP	CA	C	52.545	0.3	1
177	1	22	ASP	CB	C	42.193	0.3	1
178	1	23	GLY	HA2	H	3.512	0.020	2
179	1	23	GLY	HA3	H	3.942	0.020	2
180	1	23	GLY	CA	C	46.213	0.3	1
181	1	24	GLN	HA	H	4.425	0.020	1
182	1	24	GLN	HB2	H	1.854	0.020	2
183	1	24	GLN	HB3	H	2.204	0.020	2
184	1	24	GLN	HG2	H	2.040	0.020	2
185	1	24	GLN	HG3	H	2.201	0.020	2
186	1	24	GLN	CA	C	53.906	0.3	1
187	1	24	GLN	CB	C	29.250	0.3	1
188	1	24	GLN	CG	C	33.962	0.3	1
189	1	25	CYS	HA	H	5.096	0.020	1
190	1	25	CYS	HB2	H	2.442	0.020	2
191	1	25	CYS	HB3	H	2.650	0.020	2
192	1	25	CYS	CA	C	57.988	0.3	1
193	1	25	CYS	CB	C	28.804	0.3	1
194	1	26	TYR	HA	H	4.766	0.020	1
195	1	26	TYR	HB2	H	2.777	0.020	2
196	1	26	TYR	HB3	H	3.469	0.020	2
197	1	26	TYR	HD1	H	7.077	0.020	1
198	1	26	TYR	HD2	H	7.077	0.020	1
199	1	26	TYR	HE1	H	7.254	0.020	1
200	1	26	TYR	HE2	H	7.254	0.020	1
201	1	26	TYR	CA	C	56.986	0.3	1
202	1	26	TYR	CB	C	43.795	0.3	1
203	1	26	TYR	CD1	C	133.979	0.3	1
204	1	26	TYR	CD2	C	133.979	0.3	1
205	1	26	TYR	CE1	C	118.680	0.3	1
206	1	26	TYR	CE2	C	118.680	0.3	1
207	1	27	GLU	HA	H	4.921	0.020	1
208	1	27	GLU	HB2	H	1.963	0.020	2
209	1	27	GLU	HB3	H	2.056	0.020	2
210	1	27	GLU	HG2	H	2.221	0.020	2
211	1	27	GLU	HG3	H	2.332	0.020	2
212	1	27	GLU	CA	C	57.419	0.3	1
213	1	27	GLU	CB	C	30.461	0.3	1
214	1	27	GLU	CG	C	37.269	0.3	1
215	1	28	ALA	HA	H	5.008	0.020	1
216	1	28	ALA	HB1	H	0.678	0.020	1
217	1	28	ALA	HB2	H	0.678	0.020	1
218	1	28	ALA	HB3	H	0.678	0.020	1
219	1	28	ALA	CA	C	50.677	0.3	1
220	1	28	ALA	CB	C	23.901	0.3	1
221	1	29	GLU	HA	H	5.075	0.020	1
222	1	29	GLU	HB3	H	1.734	0.020	1
223	1	29	GLU	HG2	H	1.864	0.020	2
224	1	29	GLU	HG3	H	1.916	0.020	2
225	1	29	GLU	CA	C	54.075	0.3	1
226	1	29	GLU	CB	C	33.693	0.3	1
227	1	29	GLU	CG	C	36.699	0.3	1
228	1	30	ILE	HA	H	3.843	0.020	1
229	1	30	ILE	HB	H	1.877	0.020	1
230	1	30	ILE	HG12	H	0.349	0.020	2
231	1	30	ILE	HG13	H	1.487	0.020	2
232	1	30	ILE	HG21	H	0.601	0.020	1
233	1	30	ILE	HG22	H	0.601	0.020	1
234	1	30	ILE	HG23	H	0.601	0.020	1
235	1	30	ILE	HD11	H	0.442	0.020	1
236	1	30	ILE	HD12	H	0.442	0.020	1
237	1	30	ILE	HD13	H	0.442	0.020	1
238	1	30	ILE	CA	C	63.024	0.3	1
239	1	30	ILE	CB	C	38.110	0.3	1
240	1	30	ILE	CG1	C	28.091	0.3	1
241	1	30	ILE	CG2	C	18.589	0.3	1
242	1	30	ILE	CD1	C	14.730	0.3	1
243	1	31	GLU	HA	H	4.472	0.020	1
244	1	31	GLU	HB2	H	1.694	0.020	2
245	1	31	GLU	HB3	H	1.975	0.020	2
246	1	31	GLU	HG2	H	2.062	0.020	2
247	1	31	GLU	HG3	H	2.176	0.020	2
248	1	31	GLU	CA	C	57.188	0.3	1
249	1	31	GLU	CB	C	30.885	0.3	1
250	1	31	GLU	CG	C	35.276	0.3	1
251	1	32	GLU	HA	H	4.398	0.020	1
252	1	32	GLU	HB3	H	1.895	0.020	1
253	1	32	GLU	HG2	H	2.112	0.020	1
254	1	32	GLU	CA	C	55.812	0.3	1
255	1	32	GLU	CB	C	33.803	0.3	1
256	1	32	GLU	CG	C	36.227	0.3	1
257	1	33	ILE	HA	H	4.426	0.020	1
258	1	33	ILE	HB	H	1.576	0.020	1
259	1	33	ILE	HG12	H	0.717	0.020	2
260	1	33	ILE	HG13	H	1.339	0.020	2
261	1	33	ILE	HG21	H	0.808	0.020	1
262	1	33	ILE	HG22	H	0.808	0.020	1
263	1	33	ILE	HG23	H	0.808	0.020	1
264	1	33	ILE	HD11	H	0.717	0.020	1
265	1	33	ILE	HD12	H	0.717	0.020	1
266	1	33	ILE	HD13	H	0.717	0.020	1
267	1	33	ILE	CA	C	60.908	0.3	1
268	1	33	ILE	CB	C	41.639	0.3	1
269	1	33	ILE	CG1	C	28.812	0.3	1
270	1	33	ILE	CG2	C	17.168	0.3	1
271	1	33	ILE	CD1	C	14.007	0.3	1
272	1	34	ASP	HA	H	4.808	0.020	1
273	1	34	ASP	HB2	H	2.300	0.020	2
274	1	34	ASP	HB3	H	3.192	0.020	2
275	1	34	ASP	CA	C	51.756	0.3	1
276	1	34	ASP	CB	C	40.546	0.3	1
277	1	35	GLU	HA	H	3.922	0.020	1
278	1	35	GLU	HB2	H	1.942	0.020	2
279	1	35	GLU	HB3	H	2.062	0.020	2
280	1	35	GLU	HG2	H	2.204	0.020	2
281	1	35	GLU	HG3	H	2.315	0.020	2
282	1	35	GLU	CA	C	58.894	0.3	1
283	1	35	GLU	CB	C	29.729	0.3	1
284	1	35	GLU	CG	C	36.583	0.3	1
285	1	36	GLU	HA	H	4.025	0.020	1
286	1	36	GLU	HB2	H	1.976	0.020	2
287	1	36	GLU	HB3	H	2.062	0.020	2
288	1	36	GLU	HG3	H	2.202	0.020	1
289	1	36	GLU	CA	C	59.036	0.3	1
290	1	36	GLU	CB	C	29.283	0.3	1
291	1	36	GLU	CG	C	36.285	0.3	1
292	1	37	ASN	HA	H	4.732	0.020	1
293	1	37	ASN	HB2	H	2.338	0.020	2
294	1	37	ASN	HB3	H	2.659	0.020	2
295	1	37	ASN	CA	C	52.873	0.3	1
296	1	37	ASN	CB	C	39.556	0.3	1
297	1	38	GLY	HA2	H	3.942	0.020	1
298	1	38	GLY	HA3	H	3.942	0.020	1
299	1	38	GLY	CA	C	47.055	0.3	1
300	1	39	THR	HA	H	4.856	0.020	1
301	1	39	THR	HB	H	3.849	0.020	1
302	1	39	THR	HG21	H	0.786	0.020	1
303	1	39	THR	HG22	H	0.786	0.020	1
304	1	39	THR	HG23	H	0.786	0.020	1
305	1	39	THR	CA	C	59.561	0.3	1
306	1	39	THR	CB	C	72.501	0.3	1
307	1	39	THR	CG2	C	20.901	0.3	1
308	1	40	ALA	HA	H	4.993	0.020	1
309	1	40	ALA	HB1	H	0.978	0.020	1
310	1	40	ALA	HB2	H	0.978	0.020	1
311	1	40	ALA	HB3	H	0.978	0.020	1
312	1	40	ALA	CA	C	49.893	0.3	1
313	1	40	ALA	CB	C	22.736	0.3	1
314	1	41	ALA	HA	H	4.941	0.020	1
315	1	41	ALA	HB1	H	1.241	0.020	1
316	1	41	ALA	HB2	H	1.241	0.020	1
317	1	41	ALA	HB3	H	1.241	0.020	1
318	1	41	ALA	CA	C	50.690	0.3	1
319	1	41	ALA	CB	C	19.351	0.3	1
320	1	42	ILE	HA	H	5.212	0.020	1
321	1	42	ILE	HB	H	1.139	0.020	1
322	1	42	ILE	HG12	H	0.666	0.020	2
323	1	42	ILE	HG13	H	0.826	0.020	2
324	1	42	ILE	HG21	H	0.361	0.020	1
325	1	42	ILE	HG22	H	0.361	0.020	1
326	1	42	ILE	HG23	H	0.361	0.020	1
327	1	42	ILE	HD11	H	0.015	0.020	1
328	1	42	ILE	HD12	H	0.015	0.020	1
329	1	42	ILE	HD13	H	0.015	0.020	1
330	1	42	ILE	CA	C	58.039	0.3	1
331	1	42	ILE	CB	C	41.400	0.3	1
332	1	42	ILE	CG1	C	24.997	0.3	1
333	1	42	ILE	CG2	C	18.598	0.3	1
334	1	42	ILE	CD1	C	14.332	0.3	1
335	1	43	THR	HA	H	4.782	0.020	1
336	1	43	THR	HB	H	3.733	0.020	1
337	1	43	THR	HG21	H	0.942	0.020	1
338	1	43	THR	HG22	H	0.942	0.020	1
339	1	43	THR	HG23	H	0.942	0.020	1
340	1	43	THR	CA	C	59.881	0.3	1
341	1	43	THR	CB	C	70.446	0.3	1
342	1	43	THR	CG2	C	21.837	0.3	1
343	1	44	PHE	HA	H	4.474	0.020	1
344	1	44	PHE	HB2	H	2.633	0.020	2
345	1	44	PHE	HB3	H	2.853	0.020	2
346	1	44	PHE	HD1	H	7.113	0.020	1
347	1	44	PHE	HD2	H	7.113	0.020	1
348	1	44	PHE	HE1	H	7.317	0.020	1
349	1	44	PHE	HE2	H	7.317	0.020	1
350	1	44	PHE	CA	C	59.065	0.3	1
351	1	44	PHE	CB	C	39.549	0.3	1
352	1	44	PHE	CD1	C	131.908	0.3	1
353	1	44	PHE	CD2	C	131.908	0.3	1
354	1	44	PHE	CE1	C	131.401	0.3	1
355	1	44	PHE	CE2	C	131.401	0.3	1
356	1	45	ALA	HA	H	4.061	0.020	1
357	1	45	ALA	HB1	H	1.255	0.020	1
358	1	45	ALA	HB2	H	1.255	0.020	1
359	1	45	ALA	HB3	H	1.255	0.020	1
360	1	45	ALA	CA	C	53.262	0.3	1
361	1	45	ALA	CB	C	18.270	0.3	1
362	1	46	GLY	HA2	H	3.297	0.020	2
363	1	46	GLY	HA3	H	3.811	0.020	2
364	1	46	GLY	CA	C	45.754	0.3	1
365	1	47	TYR	HA	H	4.159	0.020	1
366	1	47	TYR	HB2	H	2.116	0.020	2
367	1	47	TYR	HB3	H	2.810	0.020	2
368	1	47	TYR	HD1	H	6.485	0.020	1
369	1	47	TYR	HD2	H	6.485	0.020	1
370	1	47	TYR	HE1	H	6.315	0.020	1
371	1	47	TYR	HE2	H	6.315	0.020	1
372	1	47	TYR	CA	C	58.858	0.3	1
373	1	47	TYR	CB	C	39.938	0.3	1
374	1	47	TYR	CD1	C	132.542	0.3	1
375	1	47	TYR	CD2	C	132.542	0.3	1
376	1	47	TYR	CE1	C	117.751	0.3	1
377	1	47	TYR	CE2	C	117.751	0.3	1
378	1	48	GLY	HA2	H	3.714	0.020	2
379	1	48	GLY	HA3	H	3.872	0.020	2
380	1	48	GLY	CA	C	45.738	0.3	1
381	1	49	ASN	HA	H	4.687	0.020	1
382	1	49	ASN	HB2	H	2.752	0.020	2
383	1	49	ASN	HB3	H	3.022	0.020	2
384	1	49	ASN	CA	C	53.286	0.3	1
385	1	49	ASN	CB	C	38.238	0.3	1
386	1	50	ALA	HA	H	5.282	0.020	1
387	1	50	ALA	HB1	H	1.294	0.020	1
388	1	50	ALA	HB2	H	1.294	0.020	1
389	1	50	ALA	HB3	H	1.294	0.020	1
390	1	50	ALA	CA	C	51.102	0.3	1
391	1	50	ALA	CB	C	21.380	0.3	1
392	1	51	GLU	HA	H	4.711	0.020	1
393	1	51	GLU	HB2	H	2.106	0.020	1
394	1	51	GLU	HG2	H	2.338	0.020	2
395	1	51	GLU	HG3	H	2.373	0.020	2
396	1	51	GLU	CA	C	55.137	0.3	1
397	1	51	GLU	CB	C	33.905	0.3	1
398	1	51	GLU	CG	C	35.847	0.3	1
399	1	52	VAL	HA	H	4.860	0.020	1
400	1	52	VAL	HB	H	1.824	0.020	1
401	1	52	VAL	HG11	H	0.742	0.020	2
402	1	52	VAL	HG12	H	0.742	0.020	2
403	1	52	VAL	HG13	H	0.742	0.020	2
404	1	52	VAL	HG21	H	0.849	0.020	2
405	1	52	VAL	HG22	H	0.849	0.020	2
406	1	52	VAL	HG23	H	0.849	0.020	2
407	1	52	VAL	CA	C	61.836	0.3	1
408	1	52	VAL	CB	C	32.556	0.3	1
409	1	52	VAL	CG1	C	20.945	0.3	1
410	1	52	VAL	CG2	C	21.384	0.3	1
411	1	53	THR	HA	H	5.117	0.020	1
412	1	53	THR	HB	H	3.753	0.020	1
413	1	53	THR	HG21	H	1.005	0.020	1
414	1	53	THR	HG22	H	1.005	0.020	1
415	1	53	THR	HG23	H	1.005	0.020	1
416	1	53	THR	CA	C	58.217	0.3	1
417	1	53	THR	CB	C	73.306	0.3	1
418	1	53	THR	CG2	C	19.842	0.3	1
419	1	54	PRO	HA	H	4.548	0.020	1
420	1	54	PRO	HB2	H	1.711	0.020	1
421	1	54	PRO	HG2	H	1.875	0.020	2
422	1	54	PRO	HG3	H	2.025	0.020	2
423	1	54	PRO	HD2	H	3.716	0.020	2
424	1	54	PRO	HD3	H	3.899	0.020	2
425	1	54	PRO	CA	C	63.313	0.3	1
426	1	54	PRO	CG	C	28.001	0.3	1
427	1	54	PRO	CD	C	52.213	0.3	1
428	1	55	LEU	HA	H	3.608	0.020	1
429	1	55	LEU	HB2	H	1.401	0.020	2
430	1	55	LEU	HB3	H	1.510	0.020	2
431	1	55	LEU	HG	H	1.146	0.020	1
432	1	55	LEU	HD11	H	0.734	0.020	2
433	1	55	LEU	HD12	H	0.734	0.020	2
434	1	55	LEU	HD13	H	0.734	0.020	2
435	1	55	LEU	HD21	H	0.603	0.020	2
436	1	55	LEU	HD22	H	0.603	0.020	2
437	1	55	LEU	HD23	H	0.603	0.020	2
438	1	55	LEU	CA	C	57.618	0.3	1
439	1	55	LEU	CB	C	42.264	0.3	1
440	1	55	LEU	CG	C	27.475	0.3	1
441	1	55	LEU	CD1	C	25.333	0.3	1
442	1	55	LEU	CD2	C	23.711	0.3	1
443	1	56	LEU	HA	H	4.173	0.020	1
444	1	56	LEU	HB3	H	1.587	0.020	1
445	1	56	LEU	HG	H	1.717	0.020	1
446	1	56	LEU	HD11	H	0.901	0.020	2
447	1	56	LEU	HD12	H	0.901	0.020	2
448	1	56	LEU	HD13	H	0.901	0.020	2
449	1	56	LEU	HD21	H	0.897	0.020	2
450	1	56	LEU	HD22	H	0.897	0.020	2
451	1	56	LEU	HD23	H	0.897	0.020	2
452	1	56	LEU	CA	C	56.631	0.3	1
453	1	56	LEU	CB	C	42.042	0.3	1
454	1	56	LEU	CG	C	26.989	0.3	1
455	1	56	LEU	CD1	C	24.674	0.3	1
456	1	56	LEU	CD2	C	23.825	0.3	1
457	1	57	ASN	HB2	H	2.547	0.020	2
458	1	57	ASN	HB3	H	2.724	0.020	2
459	1	57	ASN	CB	C	38.872	0.3	1
460	1	58	LEU	HA	H	4.479	0.020	1
461	1	58	LEU	HB2	H	0.401	0.020	2
462	1	58	LEU	HB3	H	1.510	0.020	2
463	1	58	LEU	HG	H	1.461	0.020	1
464	1	58	LEU	HD11	H	-0.205	0.020	2
465	1	58	LEU	HD12	H	-0.205	0.020	2
466	1	58	LEU	HD13	H	-0.205	0.020	2
467	1	58	LEU	HD21	H	0.408	0.020	2
468	1	58	LEU	HD22	H	0.408	0.020	2
469	1	58	LEU	HD23	H	0.408	0.020	2
470	1	58	LEU	CA	C	54.479	0.3	1
471	1	58	LEU	CB	C	42.219	0.3	1
472	1	58	LEU	CG	C	25.913	0.3	1
473	1	58	LEU	CD1	C	24.566	0.3	1
474	1	58	LEU	CD2	C	23.007	0.3	1
475	1	59	LYS	HA	H	5.134	0.020	1
476	1	59	LYS	HB2	H	1.601	0.020	2
477	1	59	LYS	HB3	H	1.904	0.020	2
478	1	59	LYS	HG2	H	1.419	0.020	1
479	1	59	LYS	HD2	H	1.614	0.020	1
480	1	59	LYS	CA	C	53.000	0.3	1
481	1	59	LYS	CB	C	34.475	0.3	1
482	1	59	LYS	CG	C	24.681	0.3	1
483	1	59	LYS	CD	C	28.798	0.3	1
484	1	60	PRO	HA	H	4.836	0.020	1
485	1	60	PRO	HB2	H	1.763	0.020	2
486	1	60	PRO	HB3	H	2.112	0.020	2
487	1	60	PRO	HG2	H	1.581	0.020	2
488	1	60	PRO	HG3	H	1.890	0.020	2
489	1	60	PRO	HD2	H	3.591	0.020	2
490	1	60	PRO	HD3	H	3.729	0.020	2
491	1	60	PRO	CA	C	62.660	0.3	1
492	1	60	PRO	CB	C	32.248	0.3	1
493	1	60	PRO	CG	C	27.444	0.3	1
494	1	60	PRO	CD	C	50.695	0.3	1
495	1	61	VAL	HA	H	3.853	0.020	1
496	1	61	VAL	HB	H	1.954	0.020	1
497	1	61	VAL	HG11	H	0.826	0.020	2
498	1	61	VAL	HG12	H	0.826	0.020	2
499	1	61	VAL	HG13	H	0.826	0.020	2
500	1	61	VAL	HG21	H	0.838	0.020	2
501	1	61	VAL	HG22	H	0.838	0.020	2
502	1	61	VAL	HG23	H	0.838	0.020	2
503	1	61	VAL	CA	C	62.773	0.3	1
504	1	61	VAL	CB	C	32.172	0.3	1
505	1	61	VAL	CG1	C	20.910	0.3	1
506	1	61	VAL	CG2	C	21.329	0.3	1
507	1	62	GLU	HA	H	4.269	0.020	1
508	1	62	GLU	HB2	H	1.849	0.020	2
509	1	62	GLU	HB3	H	2.007	0.020	2
510	1	62	GLU	HG2	H	2.165	0.020	1
511	1	62	GLU	CA	C	56.069	0.3	1
512	1	62	GLU	CB	C	30.653	0.3	1
513	1	62	GLU	CG	C	36.260	0.3	1
514	1	63	GLU	HA	H	4.236	0.020	1
515	1	63	GLU	CA	C	56.356	0.3	1
516	2	1	ZTI	H1	H	8.195	0.020	1
517	2	1	ZTI	H2	H	7.575	0.020	1
518	2	1	ZTI	H31	H	7.066	0.020	1
519	2	1	ZTI	H4	H	7.497	0.020	1
520	2	1	ZTI	H7	H	7.099	0.020	1

Release date

2023-11-06

Citation

Pharmacological perturbation of the phase-separating protein SMNDC1
Enders, L., Siklos, M., Borggrafe, J., Gaussmann, S., Koren, A., Malik, M., Tomek, T., Schuster, M., Reinis, J., Hahn, E., Rukavina, A., Reicher, A., Casteels, T., Bock, C., Winter, G.E., Hannich, J.T., Sattler, M., Kubicek, S.
Nat. Commun. (2023), 14, 4504-4504, PubMed 37587144 , DOI 10.1038/s41467-023-40124-0 , Abstract

Related entities 1. Survival of motor neuron-related-splicing factor 30, entity 1, : 1 : 4 : 2 : 4 : 100 entities Detail

Interaction partners 1. Survival of motor neuron-related-splicing factor 30, entity 1, : 32 interactors Detail

Experiments performed 7 experiments Detail

Chemical shift validation 4 contents Detail