BMRB: 34861

NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with N-(3-chlorophenyl)-2-pyrrolidin-1-ylacetamide

Authors

Buetikofer, M., Orts, J.

Assembly

V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA b

Entity

1. V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA b, entity 1 (polymer), 169 monomers, 19271.53 Da Detail

MTEYKLVVVG AVGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKSDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEK

2. V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA b, entity UA0 (non-polymer), 238.713 Da

Total weight

19510.242 Da

Max. entity weight

19271.53 Da

Source organism

Homo sapiens

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chemcal Shifts

¹H: 15 assignments Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

ID	Entity ID	Seq ID	Comp ID	Atom ID	Atom type	Val	Val err	Ambig. code
1	1	7	VAL	HG11	H	0.950	0.020	2
2	1	7	VAL	HG12	H	0.950	0.020	2
3	1	7	VAL	HG13	H	0.950	0.020	2
4	1	7	VAL	HG21	H	0.708	0.020	2
5	1	7	VAL	HG22	H	0.708	0.020	2
6	1	7	VAL	HG23	H	0.708	0.020	2
7	1	56	LEU	HD11	H	0.575	0.020	2
8	1	56	LEU	HD12	H	0.575	0.020	2
9	1	56	LEU	HD13	H	0.575	0.020	2
10	1	56	LEU	HD21	H	0.504	0.020	2
11	1	56	LEU	HD22	H	0.504	0.020	2
12	1	56	LEU	HD23	H	0.504	0.020	2
13	1	74	THR	HG21	H	1.196	0.020	1
14	1	74	THR	HG22	H	1.196	0.020	1
15	1	74	THR	HG23	H	1.196	0.020	1

Release date

2023-12-08

Citation

NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-l)piperazin-2-one
Buetikofer, M., Orts, J.

Experiments performed 2 experiments Detail

Chemical shift validation 4 contents Detail