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Solution structure of toxin 2 from centruroides noxius hoffmann,a beta scorpion neurotoxin acting on sodium channels
Authors
PINTAR, A., POSSANI, L.D., DELEPIERRE, M.
Assembly
Toxin 2 from Centruroides noxius hoffmann
Entity
1. Toxin 2 from Centruroides noxius hoffmann (polymer, Thiol state: all disulfide bound), 67 monomers, 7595.652 Da Detail

KEGYLVDKNT GCKYECLKLG DNDYCLRECK QQYGKGAGGY CYAFACWCTH LYEQAIVWPL PNKRCSX


Formula weight
7595.652 Da
Source organism
Centruroides noxius
Exptl. method
NMR
Refine. method
SIMULATED ANNEALING
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 94.0 %, Completeness: 83.0 %, Completeness (bb): 94.9 % Detail

Polymer type: polypeptide(L)

Total1H
All83.0 % (338 of 407)83.0 % (338 of 407)
Backbone94.9 % (130 of 137)94.9 % (130 of 137)
Sidechain77.0 % (208 of 270)77.0 % (208 of 270)
Aromatic91.5 % (43 of 47)91.5 % (43 of 47)
Methyl100.0 % (24 of 24)100.0 % (24 of 24)

1. Toxin 2 from Centruroides noxius hoffmann

KEGYLVDKNT GCKYECLKLG DNDYCLRECK QQYGKGAGGY CYAFACWCTH LYEQAIVWPL PNKRCSX

Sample

Pressure 1 atm, Temperature 303 K, pH 4.0


#NameIsotope labelingTypeConcentration
1Toxin 2 from Centruroides noxius hoffmann1 mM

Protein Blocks Logo
Calculated from 15 models in PDB: 1CN2, Strand ID: A Detail


Release date
2000-05-03
Citation
Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels
PINTAR, A., POSSANI, L.D., DELEPIERRE, M.
J. Mol. Biol. (1999), 287, 359-367, PubMed 10080898 , DOI 10.1006/jmbi.1999.2611 ,
Entries sharing articles Swiss-Prot: 1 entries Detail
  Swiss-Prot: P01495 released on 1986-07-21
    Title SCX2_CENNO Entity Beta-mammal toxin Cn2
Related entities 1. Toxin 2 from Centruroides noxius hoffmann, : 1 : 4 : 118 entities Detail
Experiments performed 1 experiments Detail
nullKeywords Centruroides noxius, neurotoxin, scorpion toxin, sodium channels