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Solution Structure of Myotrophin
Authors
Yan, Y., Nanduri, S., Sen, S., Quin, J.
Assembly
Myotrophin
Entity
1. Myotrophin (polymer, Thiol state: not reported), 118 monomers, 12860.62 Da Detail

MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTALEATDN QAIKALLQ


Formula weight
12860.62 Da
Source organism
Homo sapiens
Exptl. method
NMR
Refine. method
SIMULATED ANNEALING
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 98.3 %, Completeness: 87.0 %, Completeness (bb): 82.9 % Detail

Polymer type: polypeptide(L)

Total1H13C15N
All87.0 % (1169 of 1344)93.1 % (647 of 695)76.5 % (403 of 527)97.5 % (119 of 122)
Backbone82.9 % (580 of 700)95.5 % (231 of 242)69.2 % (238 of 344)97.4 % (111 of 114)
Sidechain92.3 % (694 of 752)91.8 % (416 of 453)92.8 % (270 of 291)100.0 % (8 of 8)
Aromatic68.1 % (49 of 72)69.4 % (25 of 36)65.7 % (23 of 35)100.0 % (1 of 1)
Methyl97.3 % (146 of 150)96.0 % (72 of 75)98.7 % (74 of 75)

1. Myotrophin

MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTALEATDN QAIKALLQ

Sample

Temperature 297 K, pH 6.2


#NameIsotope labelingTypeConcentration
1Myotrophin0.0 ~ 0.0 mM
2phosphate buffer50 mM

LACS Plot; CA
Referencing offset: 0.4 ppm, Outliers: 2 Detail
LACS Plot; CB
Referencing offset: 0.4 ppm, Outliers: 2 Detail
LACS Plot; HA
Referencing offset: 0.09 ppm, Outliers: 1 Detail
Protein Blocks Logo
Calculated from 44 models in PDB: 1MYO, Strand ID: A Detail


Release date
2000-07-04
Citation
Nuclear magnetic resonance assignment and secondary structure of an ankyrin-like repeat-bearing protein: myotrophin
Yan, Y., Nanduri, S., Sen, S., Quin, J.
Protein Sci. (1997), 6, 1347-1351, PubMed 9194197 , DOI 10.1002/pro.5560060625 ,
Related entities 1. Myotrophin, : 1 : 5 : 6 : 756 entities Detail
Interaction partners 1. Myotrophin, : 1 interactors Detail
Experiments performed 7 experiments Detail
nullKeywords ANK-repeat, myotrophin, NM