BMRB: 4372

Solution Structure of a Quadraplex Forming DNA and Its Intermediate

Authors

Marathias, V.M., Bolton, P.H.

Assembly

apt

Entity

1. apt (polymer), 15 monomers, 4806.023 Da Detail

GGTTGGTGTG GTTGG

Formula weight

4806.023 Da

Exptl. method

NMR

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 77.3 %, Completeness (bb): 85.7 % Detail

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Polymer type: polydeoxyribonucleotide

	Total	1H
All	77.3 % (109 of 141)	77.3 % (109 of 141)
Suger, PO4	85.7 % (90 of 105)	85.7 % (90 of 105)
Nucleobase	52.8 % (19 of 36)	52.8 % (19 of 36)
Aromatic	50.0 % (15 of 30)	50.0 % (15 of 30)
Methyl	66.7 % (4 of 6)	66.7 % (4 of 6)

1. aptamer

GGTTGGTGTG GTTGG

Show sample condition

Sample

Temperature 288 (±0.2) K, pH 7.0 (±0.1)

#	Name	Isotope labeling	Type	Concentration
1	aptamer			1.4 mM
2	NaCl			140 mM
3	KCl			5 mM
4	tris-d11			20 mM

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Release date

2000-06-16

Citation

Structures of the potassium-saturated, 2:1, and intermediate, 1:1, forms of a quadruplex DNA
Marathias, V.M., Bolton, P.H.
Nucleic Acids Res. (2000), 28, 1969-1977, PubMed 10756199 , DOI: , Abstract

Experiments performed 7 experiments Detail