Search

C-TERMINAL KH DOMAIN OF HNRNP K (KH3)
Authors
BABER, J., LIBUTTI, D., LEVENS, D., TJANDRA, N.
Assembly
hnRNP K
Entity
1. hnRNP K (polymer), 89 monomers, 9687.762 Da Detail

GSPNSYGDLG GPIITTQVTI PKDLARSIIG KGGQRIKQIR HESGASIKID EPLEGSEDRI ITITGTQDQI QNAQYLLQNS VKQYSGKFF


Formula weight
9687.762 Da
Source organism
Homo sapiens
Exptl. method
NMR
Refine. method
DISTANCE GEOMETRY AND SIMULATED ANNEALING
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 97.8 %, Completeness: 93.6 %, Completeness (bb): 96.6 % Detail

Polymer type: polypeptide(L)

Total1H13C15N
All93.6 % (962 of 1028)93.7 % (506 of 540)93.1 % (364 of 391)94.8 % (92 of 97)
Backbone96.6 % (508 of 526)96.8 % (179 of 185)96.5 % (247 of 256)96.5 % (82 of 85)
Sidechain91.6 % (531 of 580)92.1 % (327 of 355)91.1 % (194 of 213)83.3 % (10 of 12)
Aromatic25.0 % (12 of 48)25.0 % (6 of 24)25.0 % (6 of 24)
Methyl100.0 % (98 of 98)100.0 % (49 of 49)100.0 % (49 of 49)

1. hnRNP K

GSPNSYGDLG GPIITTQVTI PKDLARSIIG KGGQRIKQIR HESGASIKID EPLEGSEDRI ITITGTQDQI QNAQYLLQNS VKQYSGKFF

Sample

Pressure 1 atm, Temperature 300 (±0.4) K


#NameIsotope labelingTypeConcentration
1hnRNP K[U-99% 13C; U-99% 15N]1.0 ~ 0.0 mM

LACS Plot; CA
Referencing offset: -0.24 ppm, Outliers: 1 Detail
LACS Plot; CB
Referencing offset: -0.24 ppm, Outliers: 1 Detail
LACS Plot; HA
Referencing offset: -0.02 ppm, Outliers: 1 Detail
LACS Plot; CO
Referencing offset: 0.12 ppm, Outliers: 1 Detail
Protein Blocks Logo
Calculated from 20 models in PDB: 1KHM, Strand ID: A Detail


Release date
1999-11-28
Citation
High precision solution structure of the C-terminal KH domain of heterogeneous nuclear ribonucleoprotein K, a c-myc transcription factor
BABER, J., LIBUTTI, D., LEVENS, D., TJANDRA, N.
J. Mol. Biol. (1999), 289, 949-962, PubMed 10369774 , DOI 10.1006/jmbi.1999.2818 ,
Entries sharing articles Swiss-Prot: 1 entries Detail
  Swiss-Prot: P61978 released on 2004-06-07
    Title HNRPK_HUMAN Entity Heterogeneous nuclear ribonucleoprotein K
Related entities 1. hnRNP K, : 1 : 12 : 129 entities Detail
Interaction partners 1. hnRNP K, : 11 interactors Detail
Experiments performed 1 experiments Detail
nullKeywords C-MYC, DIPOLAR COUPLING, DNA-BINDING, HNRNP K, KH DOMAIN, NMR, RNA-BINDING, THREE-DIMENSIONAL STRUCTURE