BMRB: 4406

The cyclic peptide contryphan-R from Conus radiatus

Authors

Pallaghy, P.K., Melnikova, A.P., Jimenez, E.C., Olivera, B.M., Norton, R.S.

Assembly

contryphan-R

Entity

1. contryphan-R (polymer), 9 monomers, 991.1228 Da Detail

GCXXEPWCX

Formula weight

991.1228 Da

Entity Connection

disulfide 1 Detail

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ID	Type	Value order	Atom ID 1	Atom ID 2
1	disulfide	sing	1:CYS2:SG	1:CYS8:SG

Source organism

Dilta

Exptl. method

NMR

Refine. method

SIMULATED ANNEALING, ENERGY MINIMISATION IN CHARMM19

Data set

assigned_chemical_shifts, coupling_constants

Chem. Shift Complete

Sequence coverage: 66.7 %, Completeness: 97.1 %, Completeness (bb): 91.7 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	97.1 % (33 of 34)	97.1 % (33 of 34)
Backbone	91.7 % (11 of 12)	91.7 % (11 of 12)
Sidechain	100.0 % (22 of 22)	100.0 % (22 of 22)
Aromatic	100.0 % (6 of 6)	100.0 % (6 of 6)

1. contryphan-R

GCXXEPWCX

Show sample condition

Sample

Temperature 278 (±0.5) K, pH 3.0 (±0.2), Details pH 3.0

#	Name	Isotope labeling	Type	Concentration
1	contryphan-R			4.0 mM

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Protein Blocks Logo

Calculated from 20 models in PDB: 1QFB, Strand ID: A Detail

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Release date

2008-07-16

Citation

Solution structure of contryphan-R, a naturally occurring disulfide-bridged octapeptide containing D-tryptophan: comparison with protein loops
Pallaghy, P.K., Melnikova, A.P., Jimenez, E.C., Olivera, B.M., Norton, R.S.
Biochemistry (1999), 38, 11553-11559, PubMed 10471307 , DOI 10.1021/bi990685j , Abstract

Experiments performed 1 experiments Detail