The unusual structure of Ruminococcin C1 antimicrobial peptide confers activity against clinical pathogens
ID | Type | Value order | Atom ID 1 | Atom ID 2 |
---|---|---|---|---|
1 | thioether | sing | 1:CYS3:SG | 1:ASN16:CA |
2 | thioether | sing | 1:CYS5:SG | 1:ALA12:CA |
3 | thioether | sing | 1:CYS22:SG | 1:LYS42:CA |
4 | thioether | sing | 1:CYS26:SG | 1:ARG34:CA |
Polymer type: polypeptide(L)
Total | 1H | 13C | 15N | |
---|---|---|---|---|
All | 86.9 % (371 of 427) | 87.3 % (185 of 212) | 85.3 % (139 of 163) | 90.4 % (47 of 52) |
Backbone | 92.4 % (242 of 262) | 89.2 % (83 of 93) | 95.2 % (120 of 126) | 90.7 % (39 of 43) |
Sidechain | 81.8 % (166 of 203) | 85.7 % (102 of 119) | 74.7 % (56 of 75) | 88.9 % (8 of 9) |
Aromatic | 53.1 % (17 of 32) | 100.0 % (16 of 16) | 0.0 % (0 of 15) | 100.0 % (1 of 1) |
Methyl | 91.3 % (42 of 46) | 91.3 % (21 of 23) | 91.3 % (21 of 23) |
1. entity 1
WGCVCSGSTA VANSHNAGPA YCVGYCGNNG VVTRNANANV AKTASolvent system 90% H2O/10% D2O, Temperature 300 K, pH 6.8, Details 10 mM phosphate buffer pH 6.8
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | RUMC1 | [U-100% 13C; U-100% 15N] | 0.2 mM | |
2 | phosphate buffer | natural abundance | 10 mM |