BMRB: 5140

Solution structure of lactam analogue (DDab)of HIV gp41 600-612 loop

Authors

Phan Chan Du, A., Limal, D., Semetey, V., Dali, H., Jolivet, M., Desgranges, C., Cung, M., Briand, J., Petit, M., Muller, S.

Assembly

DDab: (ACE)IWGDSGKLI(DAB)TTA analogue of HIV GP41

Entity

1. DDab: (ACE)IWGDSGKLI(DAB)TTA analogue of HIV GP41 (polymer, Thiol state: not present), 14 monomers, 1387.580 Da Detail

XIWGDSGKLI XTTA

Formula weight

1387.58 Da

Source organism

Human immunodeficiency virus

Exptl. method

NMR

Refine. method

torsion angle dynalmics, molecular dynanmics, energy minimization

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 85.7 %, Completeness: 100.0 %, Completeness (bb): 100.0 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	100.0 % (66 of 66)	100.0 % (66 of 66)
Backbone	100.0 % (26 of 26)	100.0 % (26 of 26)
Sidechain	100.0 % (40 of 40)	100.0 % (40 of 40)
Aromatic	100.0 % (6 of 6)	100.0 % (6 of 6)
Methyl	100.0 % (9 of 9)	100.0 % (9 of 9)

1. DDab: (ACE)IWGDSGKLI(DAB)TTA analogue of HIV GP41

XIWGDSGKLI XTTA

Show sample condition

Sample

Pressure 1 atm, Temperature 298 K

#	Name	Isotope labeling	Type	Concentration
1	DDab: (ACE)IWGDSGKLI(DAB)TTA analogue of HIV GP41			4.0 mM
2	DMSO	[U-2H]		100 %

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Protein Blocks Logo

Calculated from 49 models in PDB: 1JAR, Strand ID: A Detail

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Release date

2015-04-15

Citation

Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein
Du, A.P.C., Limal, D., Semetey, V., Dali, H., Jolivet, M., Desgranges, C., Cung, M.T., Briand, J.P., Petit, M.C., Muller, S.
J. Mol. Biol. (2002), 323, 503-521, PubMed 12381305 , DOI 10.1016/s0022-2836(02)00701-5 , Abstract

Related entities 1. DDab: (ACE)IWGDSGKLI(DAB)TTA analogue of HIV GP41, : 1 : 1 : 14 entities Detail

Experiments performed 3 experiments Detail