BMRB: 5216

Y2 selective analogue-III of neuropeptide Y

Authors

Yao, S., Smith-White, M.A., Potter, E.K., Norton, R.S.

Assembly

Y2 selective analogue III of neuropeptide Y

Entity

1. Y2 selective analogue III of neuropeptide Y (polymer, Thiol state: not present), 15 monomers, 1771.014 Da Detail

XARHYKNLIE RQRYX

Formula weight

1771.014 Da

Entity Connection

covalent 1 Detail

---

ID	Type	Value order	Atom ID 1	Atom ID 2
1	covalent	sing	1:LYS6:NZ	1:GLU10:CD

Source organism

Homo sapiens

Exptl. method

NMR

Refine. method

SIMULATED ANNEALING

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 86.7 %, Completeness: 100.0 %, Completeness (bb): 100.0 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polypeptide(L)

	Total	1H
All	100.0 % (96 of 96)	100.0 % (96 of 96)
Backbone	100.0 % (26 of 26)	100.0 % (26 of 26)
Sidechain	100.0 % (70 of 70)	100.0 % (70 of 70)
Aromatic	100.0 % (10 of 10)	100.0 % (10 of 10)
Methyl	100.0 % (5 of 5)	100.0 % (5 of 5)

1. neuropeptide Y

XARHYKNLIE RQRYX

Show sample condition

Sample

Temperature 308 (±1) K, pH 5.0 (±0.2)

#	Name	Isotope labeling	Type	Concentration
1	neuropeptide Y			3.0 mM
2	TFE			40 %
3	H2O			60 %

Hide sample codition

Protein Blocks Logo

Calculated from 20 models in PDB: 1D1F, Strand ID: A Detail

---

Release date

2008-07-16

Citation

Stabilization of the helical structure of Y2-selective analogues of neuropeptide Y by lactam bridges
Yao, S., Smith-White, M.A., Potter, E.K., Norton, R.S.
J. Med. Chem. (2002), 45, 2310-2318, PubMed 12014969 , DOI: , Abstract

Related entities 1. Y2 selective analogue III of neuropeptide Y, : 1 : 60 entities Detail

Experiments performed 3 experiments Detail