BMRB: 5735

The Solution Structure of Rat Ab-(1-28) and its Interaction with Zinc: Insights into the Scarity of Amyloid Deposition in Aged Rat Brain

Authors

Huang, J., Yao, Y., Tang, W.

Assembly

rat amyloid beta-peptide 1-28

Entity

1. rat amyloid beta-peptide 1-28 (polymer, Thiol state: not present), 28 monomers, 3166.369 Da Detail

DAEFGHDSGF EVRHQKLVFF AEDVGSNK

Formula weight

3166.369 Da

Source organism

Rattus norvegicus

Exptl. method

NMR

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 94.0 %, Completeness (bb): 98.3 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	94.0 % (156 of 166)	94.0 % (156 of 166)
Backbone	98.3 % (58 of 59)	98.3 % (58 of 59)
Sidechain	91.6 % (98 of 107)	91.6 % (98 of 107)
Aromatic	66.7 % (16 of 24)	66.7 % (16 of 24)
Methyl	100.0 % (10 of 10)	100.0 % (10 of 10)

1. rat amyloid beta-peptide (1-28)

DAEFGHDSGF EVRHQKLVFF AEDVGSNK

Show sample condition

Sample

Temperature 298 (±0.5) K

#	Name	Isotope labeling	Type	Concentration
1	rat amyloid beta-peptide (1-28)			2 mM
2	DMSO			2.0 ~ 0.0 mM

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Calculated from 1 models in PDB: 1NMJ, Strand ID: A Detail

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Release date

2004-10-17

Citation

The solution structure of rat Abeta-(1-28) and its interaction with zinc ion: insights into the scarcity of amyloid deposition in aged rat brain
Huang, J., Yao, Y., Lin, J., Ye, Y.H., Sun, W.Y., Tang, W.
J. Biol. Inorg. Chem. (2004), 9, 627-635, PubMed 15160315 , DOI 10.1007/s00775-004-0556-x , Abstract

Related entities 1. rat amyloid beta-peptide 1-28, : 1 : 4 : 91 entities Detail

Interaction partners 1. rat amyloid beta-peptide 1-28, : 9 interactors Detail

Experiments performed 2 experiments Detail