BMRB: 6088

E6-bind Trp-cage (E6apn1)

Authors

Liu, Y., Liu, Z., Androphy, E., Chen, J., Baleja, J.D.

Assembly

E6apn1 peptide

Entity

1. E6apn1 peptide (polymer, Thiol state: not present), 25 monomers, 2414.694 Da Detail

XALQELLGQW LKDGGPSSGR PPPSX

Formula weight

2414.694 Da

Source organism

Papillomaviridae

Exptl. method

NMR

Refine. method

simulated annealing

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 92.0 %, Completeness: 96.4 %, Completeness (bb): 97.8 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polypeptide(L)

	Total	1H
All	96.4 % (133 of 138)	96.4 % (133 of 138)
Backbone	97.8 % (45 of 46)	97.8 % (45 of 46)
Sidechain	95.7 % (88 of 92)	95.7 % (88 of 92)
Aromatic	100.0 % (6 of 6)	100.0 % (6 of 6)
Methyl	100.0 % (9 of 9)	100.0 % (9 of 9)

1. E6apn1

XALQELLGQW LKDGGPSSGR PPPSX

Show sample condition

Sample

Pressure 1 atm, Temperature 278 K, pH 6.5

#	Name	Isotope labeling	Type	Concentration
1	E6apn1			5.0 ~ 6.0 mM
2	imidazole	[U-2H]		10 mM
3	ZnSO4			4 mM
4	DTT			1 mM
5	H2O			90 %
6	D2O			10 %

Hide sample codition

Protein Blocks Logo

Calculated from 30 models in PDB: 1RIJ, Strand ID: A Detail

---

Release date

2008-07-16

Citation

Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus
Liu, Y., Liu, Z., Androphy, E., Chen, J., Baleja, J.D.
Biochemistry (2004), 43, 7421-7431, PubMed 15182185 , DOI 10.1021/bi049552a , Abstract

Related entities 1. E6apn1 peptide, : 1 : 17 entities Detail

Experiments performed 2 experiments Detail