BMRBj - BMREntryMaster

	Total	¹H	¹⁵N
All	80.3 % (432 of 538)	77.8 % (360 of 463)	96.0 % (72 of 75)
Backbone	96.5 % (195 of 202)	96.3 % (131 of 136)	97.0 % (64 of 66)
Sidechain	70.5 % (237 of 336)	70.0 % (229 of 327)	88.9 % (8 of 9)
Aromatic	57.1 % (28 of 49)	58.3 % (28 of 48)	0.0 % (0 of 1)
Methyl	92.3 % (24 of 26)	92.3 % (24 of 26)

1. SMRT deacetylase activation domain

NGLMADPMKV YKDRQVMNMW SEQEKETFRE KFMQHPKNFG LIASFLERKT VAECVLYYYL TKKNENYK

Show sample condition

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

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Calculated from 28 models in PDB: 1XC5, Strand ID: A Detail

Release date

2005-06-01

Citation

Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors
Codina, A., Love, J.D., Li, Y., Lazar, M.A., Neuhaus, D., Schwabe, J.W.R.
Proc. Natl. Acad. Sci. U. S. A. (2005), 102, 6009-6014, PubMed 15837933 , DOI 10.1073/pnas.0500299102 , Abstract

Related entities 1. SMRT deacetylase activation domain, : 1 : 3 : 33 entities Detail

Interaction partners 1. SMRT deacetylase activation domain, : 40 interactors Detail

More details for 40 interactors identified by 26 citations

Experiments performed 7 experiments Detail

1 (1H, 1H) DQF-COSY

Instrument

#1 Model Bruker Avance (800 MHz)

#2 Model Bruker DMX (600 MHz)

#3 Model Bruker DRX (500 MHz)

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

2 (1H, 1H) DQ-correlation

Instrument

#1 Model Bruker Avance (800 MHz)

#2 Model Bruker DMX (600 MHz)

#3 Model Bruker DRX (500 MHz)

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

3 (1H, 1H) NOESY

Instrument

#1 Model Bruker Avance (800 MHz)

#2 Model Bruker DMX (600 MHz)

#3 Model Bruker DRX (500 MHz)

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

4 (1H, 1H) TOCSY

Instrument

#1 Model Bruker Avance (800 MHz)

#2 Model Bruker DMX (600 MHz)

#3 Model Bruker DRX (500 MHz)

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

5 2D 15N-HSQC

Instrument

#1 Model Bruker Avance (800 MHz)

#2 Model Bruker DMX (600 MHz)

#3 Model Bruker DRX (500 MHz)

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

6 3D 15N-NOESY-HSQC

Instrument

#1 Model Bruker Avance (800 MHz)

#2 Model Bruker DMX (600 MHz)

#3 Model Bruker DRX (500 MHz)

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

7 3D 15N-TOCSY-HSQC

Instrument

#1 Model Bruker Avance (800 MHz)

#2 Model Bruker DMX (600 MHz)

#3 Model Bruker DRX (500 MHz)

Sample #1

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Concentration
1	SMRT deacetylase activation domain	1.0 ~ 2.0 mM
2	NaCl	50 mM
3	sodium phosphate	50 mM

Sample #2

Temperature 290 (±1) K, pH 6.8 (±0.1)

#	Name	Isotope labeling	Concentration
4	SMRT deacetylase activation domain	[U-15N]	1.0 ~ 2.0 mM
5	NaCl		50 mM
6	sodium phosphate		50 mM

null

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BMRB: 6286

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Sample #2

Related entities 1. SMRT deacetylase activation domain, : 1 : 3 : 33 entities Detail

Interaction partners 1. SMRT deacetylase activation domain, : 40 interactors Detail

Experiments performed 7 experiments Detail

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