BMRB: 6681

Solution Structure Of GIP In TFE/Water

Authors

Alana, I., Parker, J.C., Hewage, C.M., Malthouse, J.P.G., Flatt, P.R., Gault, V.A., O'Harte, F.P.M.

Assembly

Gastric inhibitory polypeptide

Entity

1. Gastric inhibitory polypeptide (polymer, Thiol state: not present), 42 monomers, 4983.526 Da Detail

YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI TQ

Formula weight

4983.526 Da

Source organism

Homo sapiens

Exptl. method

NMR

Refine. method

TORSION ANGLE DYNAMICS

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 90.8 %, Completeness (bb): 98.8 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	90.8 % (248 of 273)	90.8 % (248 of 273)
Backbone	98.8 % (85 of 86)	98.8 % (85 of 86)
Sidechain	87.2 % (163 of 187)	87.2 % (163 of 187)
Aromatic	73.5 % (25 of 34)	73.5 % (25 of 34)
Methyl	100.0 % (19 of 19)	100.0 % (19 of 19)

1. Gastric inhibitory polypeptide

YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI TQ

Show sample condition

Sample

Pressure 1 atm, Temperature 298 K, pH 3.0

#	Name	Isotope labeling	Type	Concentration
1	Gastric inhibitory polypeptide			2 mM
2	TFE-d3			50 %
3	H2O			50 %

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Calculated from 20 models in PDB: 2OBU, Strand ID: A Detail

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Release date

2005-12-27

Citation

NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide
Alana, I., Hewage, C.M., Malthouse, J.P.G., Parker, J.C., Gault, V.A., O'Harte, F.P.M.
Biochem. Biophys. Res. Commun. (2004), 325, 281-286, PubMed 15522230 , DOI 10.1016/j.bbrc.2004.10.033 , Abstract

Related entities 1. Gastric inhibitory polypeptide, : 1 : 8 : 49 entities Detail

Interaction partners 1. Gastric inhibitory polypeptide, : 6 interactors Detail

Experiments performed 3 experiments Detail