BMRB: 6897

Solution structure of [Sec2,8]-ImI

Authors

Armishaw, C.J.

Assembly

Alpha-conotoxin ImI

Entity

1. Alpha-conotoxin ImI (polymer, Thiol state: all disulfide bound), 12 monomers, 1450.367 Da Detail

GXCSDPRXAW RC

Formula weight

1450.367 Da

Entity Connection

diselenide 1, disulfide 1 Detail

---

ID	Type	Value order	Atom ID 1	Atom ID 2
1	diselenide	sing	1:SEC2:SEG	1:SEC8:SEG
2	disulfide	sing	1:CYS3:SG	1:CYS12:SG

Exptl. method

NMR

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 83.3 %, Completeness: 87.7 %, Completeness (bb): 95.0 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polypeptide(L)

	Total	1H
All	87.7 % (50 of 57)	87.7 % (50 of 57)
Backbone	95.0 % (19 of 20)	95.0 % (19 of 20)
Sidechain	83.8 % (31 of 37)	83.8 % (31 of 37)
Aromatic	33.3 % (2 of 6)	33.3 % (2 of 6)
Methyl	100.0 % (1 of 1)	100.0 % (1 of 1)

1. Alpha-conotoxin ImI

GXCSDPRXAW RC

Show sample condition

Sample

Pressure 1 atm, Temperature 290 K, pH 3.5

#	Name	Isotope labeling	Type	Concentration
1	Alpha-conotoxin ImI			1 mM
2	D2O			90 %
3	H2O			10 %

Hide sample codition

Release date

2005-11-28

Citation

Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists
Armishaw, C.J., Daly, N.L., Nevin, S.T., Adams, D.J., Craik, D.J., Alewood, P.F.
J. Biol. Chem. (2006), 281, 14136-14143, PubMed 16500898 , DOI 10.1074/jbc.M512419200 , Abstract

Related entities 1. Alpha-conotoxin ImI, : 1 : 7 : 4 entities Detail

Interaction partners 1. Alpha-conotoxin ImI, : 1 interactors Detail

Experiments performed 4 experiments Detail