BMRB: 7388

sPLA2 inhibitor pip 17

Authors

Thwin, M.M., Satyanarayanajois, D.S., Nagarajarao, L.M., Sato, K., Gopalakrishnakone, P.P., Arjunan, P.

Assembly

pip17

Entity

1. pip17 (polymer, Thiol state: not present), 17 monomers, 2011.291 Da Detail

LGRVDIHVWD GVYIRGR

Formula weight

2011.291 Da

Exptl. method

solution NMR

Refine. method

TORSION ANGLE DYNAMICS

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 94.1 %, Completeness: 62.5 %, Completeness (bb): 91.9 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	62.5 % (65 of 104)	62.5 % (65 of 104)
Backbone	91.9 % (34 of 37)	91.9 % (34 of 37)
Sidechain	46.3 % (31 of 67)	46.3 % (31 of 67)
Aromatic	0.0 % (0 of 12)	0.0 % (0 of 12)
Methyl	58.3 % (7 of 12)	58.3 % (7 of 12)

1. pip17

LGRVDIHVWD GVYIRGR

Show sample condition

Sample

Solvent system DMSO, Pressure 1 atm, Details DMSO

#	Name	Isotope labeling	Type	Concentration
1	pip17	natural abundance		3 mM
2	dimethylsulfoxide			50 %
3	H2O	natural abundance		50 %

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Protein Blocks Logo

Calculated from 20 models in PDB: 2P5J, Strand ID: A Detail

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Release date

2008-02-19

Citation

Novel peptide inhibitors of human secretory phospholipase A2 with antiinflammatory activity: solution structure and molecular modeling
Thwin, M.M., Satyanarayanajois, D.S., Nagarajarao, L.M., Sato, K., Arjunan, P., Ramapatna, S.L., Kumna, P.V., Gopalakrishnakone, P.P.
J. Med. Chem. (2007), 50, 5938-5950, PubMed 17973469 , DOI 10.1021/jm070385x , Abstract

Entries sharing articles BMRB: 2 entries Detail

Related entities 1. pip17, : 1 entities Detail

Experiments performed 2 experiments Detail