Solution structure of intermediate IIa of Leech-derived tryptase inhibitor, LDTI
ID | Type | Value order | Atom ID 1 | Atom ID 2 |
---|---|---|---|---|
1 | disulfide | sing | 1:CYS6:SG | 1:CYS25:SG |
2 | disulfide | sing | 1:CYS14:SG | 1:CYS40:SG |
Polymer type: polypeptide(L)
Total | 1H | |
---|---|---|
All | 90.6 % (222 of 245) | 90.6 % (222 of 245) |
Backbone | 98.9 % (89 of 90) | 98.9 % (89 of 90) |
Sidechain | 85.8 % (133 of 155) | 85.8 % (133 of 155) |
Aromatic | 100.0 % (4 of 4) | 100.0 % (4 of 4) |
Methyl | 95.2 % (20 of 21) | 95.2 % (20 of 21) |
1. LDTI - IIa
KKVCACPKIL KPVCGSDGRT YANSCIARCN GVSIKSEGSC PTGISolvent system 90% H2O/10% D2O, Pressure 1.0 atm, Temperature 298 K, pH 1.7
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | LDTI_-_IIa | natural abundance | 1.7 mM |
Solvent system 100% D2O, Pressure 1.0 atm, Temperature 298 K, pH 1.7
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
2 | LDTI_-_IIa | natural abundance | 1.7 mM |