Structure and Stability of Duplex DNA Containing (5 S) 5 ,8-Cyclo-2 -Deoxyadenosine: An Oxidative Lesion Repair by NER.
Polymer type: polydeoxyribonucleotide
Total | 1H | |
---|---|---|
All | 64.1 % (132 of 206) | 64.1 % (132 of 206) |
Suger, PO4 | 65.3 % (96 of 147) | 65.3 % (96 of 147) |
Nucleobase | 61.0 % (36 of 59) | 61.0 % (36 of 59) |
Aromatic | 73.8 % (31 of 42) | 73.8 % (31 of 42) |
Methyl | 100.0 % (5 of 5) | 100.0 % (5 of 5) |
1. 11 mer oligonucleotide B
CGTACXCATG C2. 11 mer oligonucleotide D
GCATGTGTAC GSolvent system 100% D2O, Pressure 1 atm, Temperature 298 K, pH 6.7
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | 11 mer DNA duplex | natural abundance | 0.7 mM | |
2 | 11 mer DNA duplex | natural abundance | 0.7 mM | |
3 | D2O | natural abundance | 100 % |
Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 298 K, pH 6.7
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
4 | 11 mer DNA duplex | natural abundance | 0.7 mM | |
5 | 11 mer DNA duplex | natural abundance | 0.7 mM | |
6 | H2O | natural abundance | 90 % | |
7 | D2O | natural abundance | 10 % |