Solution structure of the major G-quadruplex formed in the human VEGF promoter: Insights into loop interactions of the parallel G-quadruplexes
Polymer type: polydeoxyribonucleotide
Total | 1H | |
---|---|---|
All | 92.9 % (196 of 211) | 92.9 % (196 of 211) |
Suger, PO4 | 100.0 % (154 of 154) | 100.0 % (154 of 154) |
Nucleobase | 73.7 % (42 of 57) | 73.7 % (42 of 57) |
Aromatic | 88.6 % (39 of 44) | 88.6 % (39 of 44) |
Methyl | 100.0 % (3 of 3) | 100.0 % (3 of 3) |
1. major G-quadruplex
CGGGGCGGGC CTTGGGCGGG GTSolvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 298 K, pH 7.0
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | major_G-quadruplex | natural abundance | 0.2 mM | |
2 | H2O | natural abundance | 90 % | |
3 | D2O | natural abundance | 10 % |