Solution NMR structure of the d(GGGTTGGGTTTTGGGTGGG) quadruplex in sodium conditions
Polymer type: polydeoxyribonucleotide
Total | 1H | 31P | |
---|---|---|---|
All | 78.2 % (154 of 197) | 86.5 % (154 of 178) | 0.0 % (0 of 19) |
Suger, PO4 | 75.7 % (115 of 152) | 86.5 % (115 of 133) | 0.0 % (0 of 19) |
Nucleobase | 86.7 % (39 of 45) | 86.7 % (39 of 45) | |
Aromatic | 84.2 % (32 of 38) | 84.2 % (32 of 38) | |
Methyl | 100.0 % (7 of 7) | 100.0 % (7 of 7) |
1. DNA (5'-D(*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*TP*GP*GP*G)-3')
GGGTTGGGTT TTGGGTGGGSolvent system 93% H2O/7% D2O, Pressure 1 atm, Temperature 293 K, pH 7.8
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | DNA (5'-D(*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*TP*GP*GP*G)-3') | natural abundance | 4.0 ~ 6.0 mM | |
2 | sodium phosphate | natural abundance | 20 mM |
Solvent system 100% D2O, Pressure 1 atm, Temperature 293 K, pH 7.8
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
3 | DNA (5'-D(*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*TP*GP*GP*G)-3') | natural abundance | 4.0 ~ 6.0 mM | |
4 | sodium phosphate | natural abundance | 20 mM |
Polymer type: polydeoxyribonucleotide
Total | 1H | 31P | |
---|---|---|---|
All | 82.7 % (326 of 394) | 86.5 % (308 of 356) | 47.4 % (18 of 38) |
Suger, PO4 | 85.9 % (261 of 304) | 91.4 % (243 of 266) | 47.4 % (18 of 38) |
Nucleobase | 72.2 % (65 of 90) | 72.2 % (65 of 90) | |
Aromatic | 67.1 % (51 of 76) | 67.1 % (51 of 76) | |
Methyl | 100.0 % (14 of 14) | 100.0 % (14 of 14) |
1. DNA (5'-D(*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*TP*GP*GP*G)-3')
GGGTTGGGTT TTGGGTGGGSolvent system 93% H2O/7% D2O, Pressure 1 atm, Temperature 278 K, pH 7.8
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | DNA (5'-D(*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*TP*GP*GP*G)-3') | natural abundance | 4.0 ~ 6.0 mM | |
2 | sodium phosphate | natural abundance | 20 mM |
Solvent system 100% D2O, Pressure 1 atm, Temperature 278 K, pH 7.8
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
3 | DNA (5'-D(*GP*GP*GP*TP*TP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*TP*GP*GP*G)-3') | natural abundance | 4.0 ~ 6.0 mM | |
4 | sodium phosphate | natural abundance | 20 mM |