Solution structure of the analgesic sea anemone peptide APETx2
Polymer type: polypeptide(L)
Total | 1H | |
---|---|---|
All | 97.8 % (225 of 230) | 97.8 % (225 of 230) |
Backbone | 96.6 % (84 of 87) | 96.6 % (84 of 87) |
Sidechain | 98.6 % (141 of 143) | 98.6 % (141 of 143) |
Aromatic | 93.8 % (30 of 32) | 93.8 % (30 of 32) |
Methyl | 100.0 % (11 of 11) | 100.0 % (11 of 11) |
1. APETx2
GTACSCGNSK GIYWFYRPSC PTDRGYTGSC RYFLGTCCTP ADSolvent system 95% H2O/5% D2O, Pressure 1 atm, Temperature 298 K, pH 6
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | APETx2 | natural abundance | 300 uM | |
2 | potassium phosphate | natural abundance | 20 mM | |
3 | H2O | natural abundance | 95 % | |
4 | D2O | [U-99% 2H] | 5 % |