BMRB: 25456

Cullin3 - BTB interface: a novel target for stapled peptides

Authors

Russo, L., Palmieri, M., Malgieri, G.

Assembly

Cullin3 - BTB interface

Entity

1. Cullin3 - BTB interface (polymer), 20 monomers, 2383.805 Da Detail

NSGLSFEXLY RXAYTMVLHK

Formula weight

2383.805 Da

Exptl. method

solution NMR

Refine. method

simulated annealing

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 90.0 %, Completeness: 92.9 %, Completeness (bb): 100.0 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polypeptide(L)

	Total	1H
All	92.9 % (105 of 113)	92.9 % (105 of 113)
Backbone	100.0 % (37 of 37)	100.0 % (37 of 37)
Sidechain	89.5 % (68 of 76)	89.5 % (68 of 76)
Aromatic	66.7 % (10 of 15)	66.7 % (10 of 15)
Methyl	80.0 % (8 of 10)	80.0 % (8 of 10)

1. entity

NSGLSFEXLY RXAYTMVLHK

Show sample condition

Sample

Solvent system trifluoroethanol/water, Pressure 1 atm, Temperature 298 K, pH 3, Details Cul349-68EN

#	Name	Isotope labeling	Type	Concentration
1	Cul349-68EN	natural abundance		1 mM
2	trifluoroethanol	natural abundance		0.0 ~ 0.0 %
3	water	natural abundance		0.0 ~ 0.0 %

Hide sample codition

Protein Blocks Logo

Calculated from 20 models in PDB: 2MYL, Strand ID: A Detail

---

Release date

2015-04-19

Citation

Cullin3-BTB interface: a novel target for stapled peptides
de Paola, I., Pirone, L., Palmieri, M., Balasco, N., Esposito, L., Russo, L., Mazz, D., Di Marcotullio, L., Di Gaetano, S., Malgieri, G., Vitagliano, L., Pedone, E., Zaccaro, L.
PLoS One (2015), 10, e0121149-e0121149, PubMed 25848797 , DOI 10.1371/journal.pone.0121149 , Abstract

Related entities 1. Cullin3 - BTB interface, : 1 : 19 : 21 entities Detail

Interaction partners 1. Cullin3 - BTB interface, : 67 interactors Detail

Experiments performed 2 experiments Detail