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Cullin3 - BTB interface: a novel target for stapled peptides
Authors
Russo, L., Palmieri, M., Malgieri, G.
Assembly
Cullin3 - BTB interface
Entity
1. Cullin3 - BTB interface (polymer), 20 monomers, 2383.805 Da Detail

NSGLSFEXLY RXAYTMVLHK


Formula weight
2383.805 Da
Exptl. method
solution NMR
Refine. method
simulated annealing
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 90.0 %, Completeness: 92.9 %, Completeness (bb): 100.0 % Detail

Polymer type: polypeptide(L)

Total1H
All92.9 % (105 of 113)92.9 % (105 of 113)
Backbone100.0 % (37 of 37)100.0 % (37 of 37)
Sidechain89.5 % (68 of 76)89.5 % (68 of 76)
Aromatic66.7 % (10 of 15)66.7 % (10 of 15)
Methyl80.0 % (8 of 10)80.0 % (8 of 10)

1. entity

NSGLSFEXLY RXAYTMVLHK

Sample

Solvent system trifluoroethanol/water, Pressure 1 atm, Temperature 298 K, pH 3, Details Cul349-68EN


#NameIsotope labelingTypeConcentration
1Cul349-68ENnatural abundance1 mM
2trifluoroethanolnatural abundance0.0 ~ 0.0 %
3waternatural abundance0.0 ~ 0.0 %

Protein Blocks Logo
Calculated from 20 models in PDB: 2MYL, Strand ID: A Detail


Release date
2015-04-19
Citation
Cullin3-BTB interface: a novel target for stapled peptides
de Paola, I., Pirone, L., Palmieri, M., Balasco, N., Esposito, L., Russo, L., Mazz, D., Di Marcotullio, L., Di Gaetano, S., Malgieri, G., Vitagliano, L., Pedone, E., Zaccaro, L.
PLoS One (2015), 10, e0121149-e0121149, PubMed 25848797 , DOI 10.1371/journal.pone.0121149 ,
Related entities 1. Cullin3 - BTB interface, : 1 : 19 : 21 entities Detail
Interaction partners 1. Cullin3 - BTB interface, : 67 interactors Detail
Experiments performed 2 experiments Detail
nullKeywords Peptide, Protein