Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1
Polymer type: polypeptide(L)
Total | 1H | 13C | |
---|---|---|---|
All | 61.2 % (120 of 196) | 95.5 % (107 of 112) | 15.5 % (13 of 84) |
Backbone | 50.9 % (55 of 108) | 97.9 % (46 of 47) | 14.8 % (9 of 61) |
Sidechain | 66.7 % (70 of 105) | 93.8 % (61 of 65) | 22.5 % (9 of 40) |
Aromatic | 50.0 % (13 of 26) | 100.0 % (13 of 13) | 0.0 % (0 of 13) |
Methyl | 75.0 % (6 of 8) | 100.0 % (4 of 4) | 50.0 % (2 of 4) |
1. entity
GHCSDPRFNY DHPEICGGAA GGSolvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 280 K, pH 4.5
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | cVc 1.1 mutant | natural abundance | 1.7 mM | |
2 | H2O | natural abundance | 90 % | |
3 | D2O | natural abundance | 10 % |