Search

Double knot toxin (DkTx)
Authors
Ramanujam, V., Mobli, M.
Assembly
Double knot toxin
Entity
1. Double knot toxin (polymer, Thiol state: all disulfide bound), 78 monomers, 8832.190 Da Detail

GDCAKEGEVC SWGKKCCDLD NFYCPMEFIP HCKKYKPYVP VTTSFNCAKE GEVCGWGSKC CHGLDCPLAF IPYCEKYR


Formula weight
8832.19 Da
Source organism
Cyriopagopus schmidti
Exptl. method
solution NMR
Refine. method
simulated annealing
Data set
assigned_chemical_shifts
Chemcal Shifts
1H: 519, 13C: 347, 15N: 75 assignments Detail
IDEntity IDSeq IDComp IDAtom IDAtom typeValVal errAmbig. code
111GLYHA2H3.8910.000
211GLYHA3H3.8910.000
311GLYCAC43.2740.000
412ASPHAH4.6610.000
512ASPHB2H2.6880.000
612ASPHB3H2.5890.000
712ASPCC175.1180.000
812ASPCAC54.7300.000
912ASPCBC41.2630.000
1013CYSHH8.0050.000
1113CYSHAH4.9710.000
1213CYSHB2H3.1710.000
1313CYSHB3H2.9680.000
1413CYSCC172.7200.000
1513CYSCAC53.5290.000
1613CYSCBC43.2150.000
1713CYSNN114.9230.001
1814ALAHH9.2330.000
1914ALAHAH4.4720.000
2014ALAHB1H1.1680.000
2114ALAHB2H1.1680.000
2214ALAHB3H1.1680.000
2314ALACC175.3060.000
2414ALACAC51.1400.000
2514ALACBC20.8040.000
2614ALANN125.2630.004
2715LYSHH8.9920.000
2815LYSHAH3.8670.000
2915LYSHB2H1.8250.000
3015LYSHB3H1.3830.000
3115LYSHG2H1.2640.000
3215LYSHG3H1.4740.000
3315LYSHD2H1.6290.000
3415LYSHD3H1.6290.000
3515LYSHE2H2.9680.000
3615LYSHE3H2.9680.000
3715LYSCC175.0280.000
3815LYSCAC55.1150.000
3915LYSCBC33.2400.000
4015LYSCGC25.5320.000
4115LYSCDC29.3360.000
4215LYSCEC41.6770.000
4315LYSNN126.1840.000
4416GLUHH7.6780.000
4516GLUHAH3.2190.000
4616GLUHB2H1.7310.000
4716GLUHB3H1.5870.000
4816GLUHG2H2.2310.000
4916GLUHG3H2.1570.000
5016GLUCC177.2330.000
5116GLUCAC58.3890.000
5216GLUCBC29.2470.000
5316GLUCGC35.8200.000
5416GLUNN120.3240.002
5517GLYHH8.8500.000
5617GLYHA2H4.2760.000
5717GLYHA3H3.5900.000
5817GLYCC173.8200.000
5917GLYCAC45.6600.000
6017GLYNN113.4860.007
6118GLUHH8.2380.000
6218GLUHAH4.5290.000
6318GLUHB2H2.2050.000
6418GLUHB3H1.9580.000
6518GLUHG2H2.1510.000
6618GLUHG3H2.0710.000
6718GLUCC175.9370.000
6818GLUCAC55.4550.000
6918GLUCBC30.7400.000
7018GLUCGC37.4400.000
7118GLUNN121.3420.003
7219VALHH8.2220.000
7319VALHAH4.2500.000
7419VALHBH1.7510.000
7519VALHG11H0.7830.000
7619VALHG12H0.7830.000
7719VALHG13H0.7830.000
7819VALHG21H0.7290.000
7919VALHG22H0.7290.000
8019VALHG23H0.7290.000
8119VALCC175.3180.000
8219VALCAC63.0390.000
8319VALCBC31.7780.000
8419VALCG1C21.0940.000
8519VALCG2C22.2000.000
8619VALNN120.7990.004
87110CYSHH7.7710.000
88110CYSHAH5.0760.000
89110CYSHB2H3.3910.000
90110CYSHB3H3.1650.000
91110CYSCC172.2710.000
92110CYSCAC52.4010.000
93110CYSCBC47.9820.000
94110CYSNN121.8930.002
95111SERHH8.3480.000
96111SERHAH4.5250.000
97111SERHB2H3.9410.000
98111SERHB3H3.7930.000
99111SERCC175.2480.000
100111SERCAC57.6560.000
101111SERCBC65.4930.000
102111SERNN112.6340.000
103112TRPHH8.6200.000
104112TRPHAH4.3640.000
105112TRPHB2H3.2890.000
106112TRPHB3H3.2890.000
107112TRPHD1H7.2690.001
108112TRPHE1H10.1230.000
109112TRPHE3H7.5090.000
110112TRPHZ2H7.4420.001
111112TRPHZ3H7.1020.000
112112TRPHH2H7.2210.000
113112TRPCC177.3400.000
114112TRPCAC59.6650.000
115112TRPCBC28.2340.000
116112TRPCD1C128.2240.000
117112TRPCE3C121.7660.000
118112TRPCZ2C115.7470.000
119112TRPCZ3C122.9530.000
120112TRPCH2C125.6840.000
121112TRPNN120.6120.001
122112TRPNE1N129.1120.000
123113GLYHH8.0400.000
124113GLYHA2H3.8610.000
125113GLYHA3H3.6230.000
126113GLYCC173.3450.000
127113GLYCAC44.8650.000
128113GLYNN104.8490.001
129114LYSHH7.4650.000
130114LYSHAH4.3710.000
131114LYSHB2H1.7870.000
132114LYSHB3H1.4000.000
133114LYSHG2H1.4580.000
134114LYSHG3H1.4580.000
135114LYSHD2H1.6380.000
136114LYSHD3H1.5580.000
137114LYSHE2H2.9420.000
138114LYSHE3H2.9420.000
139114LYSCC173.6990.000
140114LYSCAC55.5350.000
141114LYSCBC32.6670.000
142114LYSCGC25.1860.000
143114LYSCDC29.1530.000
144114LYSCEC42.3020.000
145114LYSNN125.3020.002
146115LYSHH8.2610.000
147115LYSHAH4.3540.000
148115LYSHB2H1.9220.000
149115LYSHB3H1.6390.000
150115LYSHG2H1.4590.000
151115LYSHG3H1.4590.000
152115LYSHD2H1.6480.000
153115LYSHD3H1.6480.000
154115LYSHE2H2.9650.000
155115LYSHE3H2.9650.000
156115LYSCC177.4510.000
157115LYSCAC55.2300.000
158115LYSCBC33.6310.000
159115LYSCGC24.8900.000
160115LYSCDC29.3560.000
161115LYSCEC42.0000.000
162115LYSNN123.5720.001
163116CYSHH8.8350.000
164116CYSHAH4.8690.000
165116CYSHB2H3.1020.000
166116CYSHB3H2.4130.000
167116CYSCC175.1210.000
168116CYSCAC56.8570.000
169116CYSCBC38.8790.000
170116CYSNN118.8020.004
171117CYSHH9.3390.000
172117CYSHAH4.3520.000
173117CYSHB2H3.1660.000
174117CYSHB3H2.3840.000
175117CYSCC174.4980.000
176117CYSCAC54.4680.000
177117CYSCBC40.1560.000
178117CYSNN121.3430.006
179118ASPHH8.4930.000
180118ASPHAH4.5060.000
181118ASPHB2H3.4210.000
182118ASPHB3H2.5130.000
183118ASPCC176.0480.000
184118ASPCAC53.9430.000
185118ASPCBC39.3530.000
186118ASPNN118.1460.000
187119LEUHH8.5650.000
188119LEUHAH4.8630.000
189119LEUHB2H1.8210.000
190119LEUHB3H1.7570.000
191119LEUHGH1.8990.000
192119LEUHD11H1.0110.000
193119LEUHD12H1.0110.000
194119LEUHD13H1.0110.000
195119LEUHD21H1.0030.000
196119LEUHD22H1.0030.000
197119LEUHD23H1.0030.000
198119LEUCC178.4360.000
199119LEUCAC56.4300.000
200119LEUCBC41.6760.000
201119LEUCGC26.7700.000
202119LEUCD1C24.2000.000
203119LEUCD2C26.0600.000
204119LEUNN122.5540.003
205120ASPHH8.2660.000
206120ASPHAH4.5880.000
207120ASPHB2H2.6600.000
208120ASPHB3H2.6910.000
209120ASPCC176.6730.000
210120ASPCAC56.7140.000
211120ASPCBC40.9380.000
212120ASPNN117.4840.001
213121ASNHH8.0230.000
214121ASNHAH4.8710.000
215121ASNHB2H2.5570.000
216121ASNHB3H2.1630.000
217121ASNHD21H6.9920.000
218121ASNHD22H8.8340.002
219121ASNCC173.4810.000
220121ASNCAC54.3100.000
221121ASNCBC43.1410.000
222121ASNNN114.4600.000
223121ASNND2N118.8630.000
224122PHEHH8.4680.000
225122PHEHAH5.3560.000
226122PHEHB2H3.0900.000
227122PHEHB3H2.6630.000
228122PHEHD1H7.2530.000
229122PHEHD2H7.2530.000
230122PHEHE1H7.3210.000
231122PHEHE2H7.3210.000
232122PHEHZH7.2530.000
233122PHECC173.4650.000
234122PHECAC56.9140.000
235122PHECBC43.0240.000
236122PHECD1C130.2070.000
237122PHECD2C130.2070.000
238122PHECE1C131.0990.000
239122PHECE2C131.0990.000
240122PHECZC130.2070.000
241122PHENN120.7470.002
242123TYRHH9.2180.000
243123TYRHAH4.8060.000
244123TYRHB2H2.6500.000
245123TYRHB3H2.7760.000
246123TYRHD1H6.4130.000
247123TYRHD2H6.4130.000
248123TYRHE1H6.4860.000
249123TYRHE2H6.4860.000
250123TYRCC171.6080.000
251123TYRCAC54.7160.000
252123TYRCBC41.7670.000
253123TYRCD1C134.7090.000
254123TYRCD2C134.7090.002
255123TYRCE1C117.9620.000
256123TYRCE2C117.9620.000
257123TYRNN115.6080.004
258124CYSHH8.7590.000
259124CYSHAH5.0520.000
260124CYSHB2H3.1570.000
261124CYSHB3H3.0650.000
262124CYSCAC51.6700.000
263124CYSCBC41.1250.000
264124CYSNN122.4810.000
265125PROHAH4.5150.000
266125PROHB2H2.1690.000
267125PROHB3H1.9370.000
268125PROHG2H1.9000.000
269125PROHG3H1.9000.000
270125PROHD2H3.7560.000
271125PROHD3H3.3940.000
272125PROCC175.1670.000
273125PROCAC62.6410.000
274125PROCBC33.4500.000
275125PROCGC27.1740.000
276125PROCDC52.3500.000
277126METHH8.5530.000
278126METHAH4.5230.000
279126METHB2H2.1040.000
280126METHB3H1.9460.000
281126METHG2H2.5050.000
282126METHG3H2.5730.000
283126METHE1H2.0570.000
284126METHE2H2.0570.000
285126METHE3H2.0570.000
286126METCC174.9330.000
287126METCAC54.5730.000
288126METCBC30.4710.000
289126METCGC32.0200.000
290126METCEC16.9910.000
291126METNN120.0780.003
292127GLUHH7.2400.000
293127GLUHAH4.5190.000
294127GLUHB2H2.1350.000
295127GLUHB3H1.5020.000
296127GLUHG2H2.2050.000
297127GLUHG3H1.9550.000
298127GLUCC175.1570.000
299127GLUCAC54.1340.000
300127GLUCBC33.7800.000
301127GLUCGC36.0900.000
302127GLUNN121.7300.004
303128PHEHH8.4730.000
304128PHEHAH4.3400.000
305128PHEHB2H3.1880.000
306128PHEHB3H3.0400.000
307128PHEHD1H7.2880.000
308128PHEHD2H7.2880.000
309128PHEHE1H7.3220.000
310128PHEHE2H7.3220.000
311128PHEHZH7.2880.000
312128PHECC176.6530.000
313128PHECAC61.0810.000
314128PHECBC38.9060.000
315128PHECD1C130.8950.000
316128PHECD2C130.8950.000
317128PHECE1C130.8950.000
318128PHECE2C130.8950.000
319128PHECZC130.8950.000
320128PHENN121.4770.008
321129ILEHH8.1650.000
322129ILEHAH4.1930.000
323129ILEHBH1.8610.000
324129ILEHG12H1.2330.000
325129ILEHG13H1.2330.000
326129ILEHG21H0.6410.000
327129ILEHG22H0.6410.000
328129ILEHG23H0.6410.000
329129ILEHD11H0.7950.000
330129ILEHD12H0.7950.000
331129ILEHD13H0.7950.000
332129ILECAC58.8800.000
333129ILECBC37.3800.000
334129ILECG1C26.7000.000
335129ILECG2C18.2300.000
336129ILECD1C13.0000.000
337129ILENN118.3090.000
338130PROHAH4.4510.000
339130PROHB2H2.1810.000
340130PROHB3H1.9680.000
341130PROHG2H1.8750.000
342130PROHG3H1.8750.000
343130PROHD2H3.6150.000
344130PROHD3H3.6150.000
345130PROCC175.4340.000
346130PROCAC62.6800.000
347130PROCBC33.6400.000
348130PROCGC27.1500.000
349130PROCDC50.2270.000
350131HISHH7.3310.000
351131HISHAH5.1240.000
352131HISHB2H2.8070.000
353131HISHB3H2.4690.000
354131HISHD2H7.1090.000
355131HISHE1H8.4440.000
356131HISCC174.3480.000
357131HISCAC53.3000.000
358131HISCBC31.0040.000
359131HISCD2C120.3540.000
360131HISCE1C137.3660.000
361131HISNN114.3340.001
362132CYSHH8.1410.000
363132CYSHAH4.4740.000
364132CYSHB2H2.6500.000
365132CYSHB3H3.0740.000
366132CYSCC175.8580.000
367132CYSCAC58.9500.000
368132CYSCBC41.9130.000
369132CYSNN117.7570.007
370133LYSHH8.9960.001
371133LYSHAH4.8720.000
372133LYSHB2H1.5600.000
373133LYSHB3H1.3430.000
374133LYSHG2H1.3730.000
375133LYSHG3H1.3730.000
376133LYSHD2H1.6440.000
377133LYSHD3H1.6440.000
378133LYSHE2H3.0410.000
379133LYSHE3H3.0410.000
380133LYSCC174.0550.000
381133LYSCAC54.5940.000
382133LYSCBC36.6870.000
383133LYSCGC24.6870.000
384133LYSCDC29.3560.000
385133LYSCEC42.0830.000
386133LYSNN125.6260.008
387134LYSHH8.7780.000
388134LYSHAH4.2490.000
389134LYSHB2H1.5650.000
390134LYSHB3H1.6740.000
391134LYSHG2H1.2470.000
392134LYSHG3H1.2470.000
393134LYSHD2H1.5590.000
394134LYSHD3H1.5590.000
395134LYSHE2H2.9420.000
396134LYSHE3H2.8830.000
397134LYSCC177.7760.000
398134LYSCAC56.2900.000
399134LYSCBC33.8400.000
400134LYSCGC25.6600.000
401134LYSCDC29.3560.000
402134LYSCEC41.9730.000
403134LYSNN123.5780.000
404135TYRHH7.9850.000
405135TYRHAH4.4700.000
406135TYRHB2H2.8700.000
407135TYRHB3H2.6740.000
408135TYRHD1H6.7660.000
409135TYRHD2H6.7660.000
410135TYRHE1H6.5160.000
411135TYRHE2H6.5160.000
412135TYRCC175.5260.000
413135TYRCAC59.5590.000
414135TYRCBC39.4600.000
415135TYRCD1C133.9490.000
416135TYRCD2C133.9490.000
417135TYRCE1C119.2710.000
418135TYRCE2C119.2710.000
419135TYRNN123.1320.007
420136LYSHH8.1560.000
421136LYSHAH4.5600.000
422136LYSHB2H1.7030.000
423136LYSHB3H1.5850.000
424136LYSHG2H1.3800.000
425136LYSHG3H1.3800.000
426136LYSHD2H1.6470.000
427136LYSHD3H1.6470.000
428136LYSHE2H2.9900.000
429136LYSHE3H2.9900.000
430136LYSCAC53.5950.000
431136LYSCBC32.9400.000
432136LYSCGC24.4840.000
433136LYSCDC29.5590.000
434136LYSCEC42.5000.000
435136LYSNN122.4350.001
436137PROHAH4.2860.000
437137PROHB2H2.2010.000
438137PROHB3H2.2420.000
439137PROHG2H1.9200.000
440137PROHG3H1.9200.000
441137PROHD2H3.5700.000
442137PROHD3H3.5700.000
443137PROCC176.3240.000
444137PROCAC63.0230.000
445137PROCBC32.0500.000
446137PROCGC27.6800.000
447137PROCDC50.7260.000
448138TYRHH8.2230.000
449138TYRHAH4.4780.000
450138TYRHB2H3.0080.000
451138TYRHB3H2.8420.000
452138TYRHD1H7.0470.000
453138TYRHD2H7.0470.000
454138TYRHE1H6.7650.000
455138TYRHE2H6.7650.000
456138TYRCC175.0280.000
457138TYRCAC57.8870.000
458138TYRCBC38.6500.000
459138TYRCD1C134.0020.000
460138TYRCD2C134.0020.000
461138TYRCE1C119.1010.000
462138TYRCE2C119.1010.000
463138TYRNN120.8430.008
464139VALHH7.7690.000
465139VALHAH4.2620.000
466139VALHBH1.8840.000
467139VALHG11H0.8450.000
468139VALHG12H0.8450.000
469139VALHG13H0.8450.000
470139VALHG21H0.8140.000
471139VALHG22H0.8140.000
472139VALHG23H0.8140.000
473139VALCAC59.2620.000
474139VALCBC33.0400.000
475139VALCG1C21.1000.000
476139VALCG2C20.4300.000
477139VALNN126.0860.001
478140PROHAH4.2820.000
479140PROHB2H1.8610.000
480140PROHB3H1.7600.000
481140PROHG2H1.9150.000
482140PROHG3H1.9150.000
483140PROHD2H3.5710.000
484140PROHD3H3.5710.000
485140PROCC176.7150.000
486140PROCAC62.6000.000
487140PROCBC32.0410.000
488140PROCGC26.8940.000
489140PROCDC50.4130.000
490141VALHH8.1590.000
491141VALHAH4.1330.000
492141VALHBH2.0660.000
493141VALHG11H0.9230.000
494141VALHG12H0.9230.000
495141VALHG13H0.9230.000
496141VALHG21H0.9390.000
497141VALHG22H0.9390.000
498141VALHG23H0.9390.000
499141VALCC176.5760.000
500141VALCAC62.3400.000
501141VALCBC32.9100.000
502141VALCG1C21.3000.000
503141VALCG2C20.4400.000
504141VALNN120.2510.008
505142THRHH8.2290.000
506142THRHAH4.4260.000
507142THRHBH4.1970.000
508142THRHG21H1.1520.000
509142THRHG22H1.1520.000
510142THRHG23H1.1520.000
511142THRCC174.5620.000
512142THRCAC61.7110.000
513142THRCBC69.8600.000
514142THRCG2C21.5400.000
515142THRNN117.8540.000
516143THRHH8.1670.000
517143THRHAH4.3520.000
518143THRHBH4.1960.000
519143THRHG21H1.1510.000
520143THRHG22H1.1510.000
521143THRHG23H1.1510.000
522143THRCC174.2860.000
523143THRCAC61.6830.014
524143THRCBC69.8700.000
525143THRCG2C21.3800.000
526143THRNN116.1910.001
527144SERHH8.2240.000
528144SERHAH4.4240.000
529144SERHB2H3.7680.000
530144SERHB3H3.7680.000
531144SERCC173.9450.000
532144SERCAC58.2170.000
533144SERCBC63.8660.000
534144SERNN117.6270.004
535145PHEHH8.2240.000
536145PHEHAH4.6460.000
537145PHEHB2H3.1650.001
538145PHEHB3H2.9940.000
539145PHEHD1H7.2490.000
540145PHEHD2H7.2490.000
541145PHEHE1H7.3220.000
542145PHEHE2H7.3220.000
543145PHEHZH7.2490.000
544145PHECC175.3950.000
545145PHECAC57.6960.000
546145PHECBC39.6200.000
547145PHECD1C132.9080.004
548145PHECD2C132.9080.000
549145PHECE1C132.9060.002
550145PHECE2C132.9060.000
551145PHECZC132.9140.000
552145PHENN121.7120.003
553146ASNHH8.3490.000
554146ASNHAH4.7300.000
555146ASNHB2H2.7720.000
556146ASNHB3H2.6780.000
557146ASNHD21H7.5670.000
558146ASNHD22H6.9030.001
559146ASNCC174.0610.000
560146ASNCAC52.9230.000
561146ASNCBC38.9280.000
562146ASNNN120.5500.006
563146ASNND2N112.8410.000
564147CYSHH7.9700.000
565147CYSHAH4.8120.000
566147CYSHB2H3.0870.000
567147CYSHB3H2.9920.000
568147CYSCC172.3420.000
569147CYSCAC54.2420.000
570147CYSCBC42.9210.000
571147CYSNN116.7240.001
572148ALAHH8.9600.000
573148ALAHAH4.4340.000
574148ALAHB1H1.2520.000
575148ALAHB2H1.2520.000
576148ALAHB3H1.2520.000
577148ALACC174.1270.000
578148ALACAC51.9950.000
579148ALACBC19.9560.000
580148ALANN125.7340.005
581149LYSHH8.4290.000
582149LYSHAH4.0450.000
583149LYSHB2H1.9230.000
584149LYSHB3H1.4580.000
585149LYSHG2H1.3860.000
586149LYSHG3H1.5710.000
587149LYSHD2H1.6490.000
588149LYSHD3H1.6490.000
589149LYSHE2H2.9720.000
590149LYSHE3H2.9720.000
591149LYSCC175.3490.000
592149LYSCAC54.6430.000
593149LYSCBC33.8570.000
594149LYSCGC25.5200.000
595149LYSCDC29.2630.000
596149LYSCEC42.1930.000
597149LYSNN122.7330.001
598150GLUHH8.3350.000
599150GLUHAH3.4680.000
600150GLUHB2H1.8630.000
601150GLUHB3H1.8630.000
602150GLUHG2H2.2240.000
603150GLUHG3H2.1200.000
604150GLUCC177.5950.000
605150GLUCAC58.6240.000
606150GLUCBC29.4650.000
607150GLUCGC36.0000.000
608150GLUNN119.8070.002
609151GLYHH9.0110.000
610151GLYHA2H4.2110.000
611151GLYHA3H3.5830.000
612151GLYCC173.4020.000
613151GLYCAC45.6070.000
614151GLYNN113.0780.000
615152GLUHH8.1590.000
616152GLUHAH4.6230.000
617152GLUHB2H2.0110.000
618152GLUHB3H2.3340.000
619152GLUHG2H2.1560.000
620152GLUHG3H2.0700.000
621152GLUCC175.7200.000
622152GLUCAC55.2350.000
623152GLUCBC30.7830.000
624152GLUCGC37.6200.000
625152GLUNN119.8250.002
626153VALHH8.2410.000
627153VALHAH4.2820.000
628153VALHBH1.8630.000
629153VALHG11H0.8440.000
630153VALHG12H0.8440.000
631153VALHG13H0.8440.000
632153VALHG21H0.8570.000
633153VALHG22H0.8570.000
634153VALHG23H0.8570.000
635153VALCC175.2290.000
636153VALCAC62.9800.000
637153VALCBC32.2700.000
638153VALCG1C21.3600.000
639153VALCG2C21.9900.000
640153VALNN120.4810.002
641154CYSHH7.9980.000
642154CYSHAH5.0990.001
643154CYSHB2H3.3460.000
644154CYSHB3H3.2680.000
645154CYSCC173.1080.000
646154CYSCAC53.1890.000
647154CYSCBC48.5700.000
648154CYSNN120.1770.006
649155GLYHH7.8990.000
650155GLYHA2H4.0320.000
651155GLYHA3H3.7440.000
652155GLYCC174.2550.000
653155GLYCAC44.8170.000
654155GLYNN106.2860.001
655156TRPHH8.5140.000
656156TRPHAH4.3470.000
657156TRPHB2H3.2910.000
658156TRPHB3H3.1630.000
659156TRPHD1H7.2220.001
660156TRPHE1H10.0830.000
661156TRPHE3H7.5650.000
662156TRPHZ2H7.3360.000
663156TRPHZ3H7.1400.000
664156TRPHH2H7.1970.000
665156TRPCC176.9490.000
666156TRPCAC58.8970.000
667156TRPCBC27.8800.000
668156TRPCD1C128.1310.000
669156TRPCE3C121.7670.000
670156TRPCZ2C115.5400.000
671156TRPCZ3C123.1190.000
672156TRPCH2C125.3950.000
673156TRPNN121.6200.003
674156TRPNE1N129.1090.009
675157GLYHH8.3680.000
676157GLYHA2H4.0000.000
677157GLYHA3H3.6270.000
678157GLYCC174.2500.000
679157GLYCAC45.2060.000
680157GLYNN108.7650.004
681158SERHH7.7200.000
682158SERHAH4.6490.000
683158SERHB2H3.7630.000
684158SERHB3H3.6370.000
685158SERCC173.0350.000
686158SERCAC57.2850.000
687158SERCBC64.2010.000
688158SERNN116.7400.002
689159LYSHH8.5060.000
690159LYSHAH4.5270.000
691159LYSHB2H1.8300.000
692159LYSHB3H1.6890.000
693159LYSHG2H1.4310.000
694159LYSHG3H1.4310.000
695159LYSHD2H1.6460.000
696159LYSHD3H1.6460.000
697159LYSHE2H2.9740.000
698159LYSHE3H2.9740.000
699159LYSCC176.9440.000
700159LYSCAC54.8660.000
701159LYSCBC33.8570.000
702159LYSCGC24.6870.000
703159LYSCDC28.9500.000
704159LYSCEC42.3200.000
705159LYSNN124.4090.000
706160CYSHH9.1170.000
707160CYSHAH5.1010.000
708160CYSHB2H3.1530.000
709160CYSHB3H2.5330.000
710160CYSCC176.3600.000
711160CYSCAC55.8560.000
712160CYSCBC40.7540.000
713160CYSNN120.5200.002
714161CYSHH9.5810.000
715161CYSHAH4.5100.000
716161CYSHB2H3.3920.000
717161CYSHB3H2.5460.000
718161CYSCC172.4610.000
719161CYSCAC54.2400.000
720161CYSCBC40.4600.000
721161CYSNN121.7450.002
722162HISHH8.4600.000
723162HISHAH4.3460.000
724162HISHB2H3.2350.000
725162HISHB3H3.0700.000
726162HISHD2H7.2440.000
727162HISHE1H8.3350.000
728162HISCC175.6220.000
729162HISCAC58.2820.000
730162HISCBC29.2500.000
731162HISCD2C121.1220.000
732162HISCE1C138.3670.000
733162HISNN117.4810.005
734163GLYHH8.6130.001
735163GLYHA2H4.1540.000
736163GLYHA3H3.4380.000
737163GLYCC173.0460.000
738163GLYCAC44.7330.000
739163GLYNN113.3780.002
740164LEUHH7.6320.000
741164LEUHAH4.8670.000
742164LEUHB2H2.0900.000
743164LEUHB3H1.1560.000
744164LEUHGH1.3240.000
745164LEUHD11H0.6210.000
746164LEUHD12H0.6210.000
747164LEUHD13H0.6210.000
748164LEUHD21H0.8070.000
749164LEUHD22H0.8070.000
750164LEUHD23H0.8070.000
751164LEUCC174.8250.000
752164LEUCAC52.8530.000
753164LEUCBC44.7110.000
754164LEUCGC26.6000.000
755164LEUCD1C23.3710.000
756164LEUCD2C26.7970.000
757164LEUNN119.8340.003
758165ASPHH9.2890.000
759165ASPHAH4.8130.000
760165ASPHB2H2.3480.000
761165ASPHB3H2.1430.000
762165ASPCC173.6960.000
763165ASPCAC52.5700.000
764165ASPCBC44.8610.000
765165ASPNN120.2350.003
766166CYSHH8.4080.000
767166CYSHAH5.2490.000
768166CYSHB2H3.2410.000
769166CYSHB3H3.0750.000
770166CYSCAC52.3200.000
771166CYSCBC41.0720.000
772166CYSNN123.1590.004
773167PROHAH4.4460.000
774167PROHB2H2.2350.000
775167PROHB3H1.8800.000
776167PROHG2H2.0460.000
777167PROHG3H1.9430.000
778167PROHD2H4.0000.000
779167PROHD3H3.5610.000
780167PROCC175.2100.000
781167PROCAC62.7100.000
782167PROCBC32.9500.000
783167PROCGC27.1000.000
784167PROCDC52.1700.000
785168LEUHH8.1460.000
786168LEUHAH4.2530.000
787168LEUHB2H1.5280.000
788168LEUHB3H1.5280.000
789168LEUHGH1.5470.000
790168LEUHD11H0.8660.000
791168LEUHD12H0.8660.000
792168LEUHD13H0.8660.000
793168LEUHD21H0.8010.000
794168LEUHD22H0.8010.000
795168LEUHD23H0.8010.000
796168LEUCC176.0010.000
797168LEUCAC55.0390.000
798168LEUCBC40.5200.000
799168LEUCGC27.1760.000
800168LEUCD1C24.8000.000
801168LEUCD2C23.9100.000
802168LEUNN119.9510.001
803169ALAHH7.4240.000
804169ALAHAH4.3730.000
805169ALAHB1H1.1900.000
806169ALAHB2H1.1900.000
807169ALAHB3H1.1900.000
808169ALACC176.0230.000
809169ALACAC50.8700.000
810169ALACBC21.7830.000
811169ALANN125.9040.002
812170PHEHH8.4020.000
813170PHEHAH4.3540.000
814170PHEHB2H3.1850.000
815170PHEHB3H3.0670.000
816170PHEHD1H7.3210.000
817170PHEHD2H7.3210.000
818170PHEHE1H7.3800.000
819170PHEHE2H7.3800.000
820170PHEHZH7.3210.000
821170PHECC176.7540.000
822170PHECAC61.1260.000
823170PHECBC38.6340.000
824170PHECD1C132.7220.003
825170PHECD2C132.7220.000
826170PHECE1C132.6860.000
827170PHECE2C132.6860.000
828170PHECZC132.7270.000
829170PHENN120.6190.004
830171ILEHH7.7750.000
831171ILEHAH4.2570.000
832171ILEHBH1.7420.000
833171ILEHG12H1.3320.000
834171ILEHG13H1.3320.000
835171ILEHG21H0.5630.000
836171ILEHG22H0.5630.000
837171ILEHG23H0.5630.000
838171ILEHD11H0.8050.000
839171ILEHD12H0.8050.000
840171ILEHD13H0.8050.000
841171ILECAC58.6900.000
842171ILECBC38.6000.000
843171ILECG1C26.9900.000
844171ILECG2C17.6100.000
845171ILECD1C12.9840.000
846171ILENN117.4030.003
847172PROHAH4.3410.000
848172PROHB2H2.0840.000
849172PROHB3H2.0220.000
850172PROHG2H2.1470.000
851172PROHG3H2.1470.000
852172PROHD2H3.6110.000
853172PROHD3H3.6110.000
854172PROCC174.6160.000
855172PROCAC62.0400.000
856172PROCBC32.6940.000
857172PROCGC26.6500.000
858172PROCDC50.4100.000
859173TYRHH7.3760.000
860173TYRHAH5.0420.000
861173TYRHB2H2.6150.000
862173TYRHB3H2.4390.000
863173TYRHD1H6.8900.000
864173TYRHD2H6.8900.000
865173TYRHE1H6.6800.000
866173TYRHE2H6.6800.000
867173TYRCC176.3310.000
868173TYRCAC55.1050.000
869173TYRCBC41.4180.000
870173TYRCD1C134.3830.000
871173TYRCD2C134.3830.000
872173TYRCE1C119.1100.000
873173TYRCE2C119.1100.000
874173TYRNN116.9030.006
875174CYSHH8.6790.000
876174CYSHAH4.7620.000
877174CYSHB2H3.2750.000
878174CYSHB3H2.6510.000
879174CYSCC176.1270.000
880174CYSCAC57.2190.000
881174CYSCBC41.5670.000
882174CYSNN118.1500.001
883175GLUHH9.2850.000
884175GLUHAH4.9400.000
885175GLUHB2H2.0810.000
886175GLUHB3H1.9570.000
887175GLUHG2H2.3540.000
888175GLUHG3H2.3540.000
889175GLUCC174.5000.000
890175GLUCAC54.0080.000
891175GLUCBC33.5920.000
892175GLUCGC34.5360.000
893175GLUNN122.6580.005
894176LYSHH8.8500.000
895176LYSHAH4.3160.000
896176LYSHB2H1.8000.000
897176LYSHB3H1.5960.000
898176LYSHG2H1.3390.000
899176LYSHG3H1.4130.000
900176LYSHD2H1.6470.000
901176LYSHD3H1.6470.000
902176LYSHE2H2.9650.000
903176LYSHE3H2.9650.000
904176LYSCC176.6800.000
905176LYSCAC57.0630.000
906176LYSCBC33.2500.000
907176LYSCGC25.2960.000
908176LYSCDC29.2790.000
909176LYSCEC41.8400.000
910176LYSNN122.3030.003
911177TYRHH8.1010.000
912177TYRHAH4.4930.000
913177TYRHB2H2.9800.000
914177TYRHB3H2.8340.000
915177TYRHD1H7.0530.000
916177TYRHD2H7.0530.000
917177TYRHE1H6.7650.000
918177TYRHE2H6.7650.000
919177TYRCC175.2590.000
920177TYRCAC58.4000.000
921177TYRCBC38.6500.000
922177TYRCD1C133.9930.000
923177TYRCD2C133.9930.000
924177TYRCE1C119.1230.000
925177TYRCE2C119.1230.000
926177TYRNN122.9550.004
927178ARGHH7.9310.000
928178ARGHAH4.0940.000
929178ARGHB2H1.6550.000
930178ARGHB3H1.7770.000
931178ARGHG2H1.5240.000
932178ARGHG3H1.5240.000
933178ARGHD2H3.1400.000
934178ARGHD3H3.1400.000
935178ARGHEH7.1870.000
936178ARGCAC57.4500.000
937178ARGCBC31.7110.000
938178ARGCGC27.2100.000
939178ARGCDC43.5400.000
940178ARGNN128.0590.001
941178ARGNEN113.4080.000

LACS Plot; CA
Referencing offset: -0.05 ppm, Outliers: 1 Detail
LACS Plot; CB
Referencing offset: -0.05 ppm, Outliers: 1 Detail
LACS Plot; HA
Referencing offset: 0.02 ppm, Outliers: 2 Detail
LACS Plot; CO
Referencing offset: 0.41 ppm, Outliers: 3 Detail
Protein Blocks Logo
Calculated from 20 models in PDB: 6CUC, Strand ID: A Detail


Release date
2018-03-25
Citation
Structural Basis of the Bivalency of the TRPV1 Agonist DkTx
Ramanujam, V., Crawford, T., Cristofori-Armstrong, B., Deuis, J.R., Jia, X., Maxwell, M.J., Jami, S., Ma, L., Vetter, I., Mobli, M.
Angew. Chem Int Ed Engl. (2024), 63, e202314621-e202314621, PubMed 37953402 , DOI 10.1002/anie.202314621 ,
Related entities 1. Double knot toxin, : 1 : 6 entities Detail
Interaction partners 1. Double knot toxin, : 1 interactors Detail
Experiments performed 9 experiments Detail
NMR combined restraints 3 contents Detail