Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
ID | Type | Value order | Atom ID 1 | Atom ID 2 |
---|---|---|---|---|
1 | na | sing | 1:CYS9:SG | 3:ZN1:ZN |
2 | na | sing | 1:CYS12:SG | 3:ZN1:ZN |
3 | na | sing | 1:HIS33:ND1 | 3:ZN1:ZN |
4 | na | sing | 1:CYS36:SG | 3:ZN1:ZN |
5 | na | sing | 1:CYS25:SG | 3:ZN1:ZN |
6 | na | sing | 1:CYS28:SG | 3:ZN1:ZN |
7 | na | sing | 1:CYS55:SG | 3:ZN1:ZN |
8 | na | sing | 1:CYS58:SG | 3:ZN1:ZN |
Polymer type: polypeptide(L)
Total | 1H | 13C | 15N | |
---|---|---|---|---|
All | 75.1 % (614 of 818) | 77.8 % (329 of 423) | 70.6 % (226 of 320) | 78.7 % (59 of 75) |
Backbone | 74.4 % (326 of 438) | 80.1 % (121 of 151) | 69.4 % (150 of 216) | 77.5 % (55 of 71) |
Sidechain | 76.8 % (344 of 448) | 76.5 % (208 of 272) | 76.7 % (132 of 172) | 100.0 % (4 of 4) |
Aromatic | 70.6 % (48 of 68) | 82.4 % (28 of 34) | 57.6 % (19 of 33) | 100.0 % (1 of 1) |
Methyl | 86.4 % (57 of 66) | 84.8 % (28 of 33) | 87.9 % (29 of 33) |
1. entity 1
GSHMSLVTCP ICHAPYVEED LLIQCRHCER WMHAGCESLF TEDDVEQAAD EGFDCVSCQP YVVK2. entity 2
XGKGGAXRHR KVXSolvent system 93% H2O/7% D2O, Pressure 1 atm, Temperature 298 K, pH 7.0, Details 2.5 mM [U-13C; U-15N] MLL4 PHD6, 7.5 mM histone H4K16ac (11-21) peptide, 93% H2O/7% D2O
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | MLL4 PHD6 | [U-13C; U-15N] | 2.5 mM | |
2 | histone H4K16ac (11-21) peptide | natural abundance | 7.5 mM | |
3 | NaCl buffer | natural abundance | 100 mM |