Structure of the cryptic HMA domain of the human copper transporter ATP7A
Polymer type: polypeptide(L)
Total | 1H | 13C | 15N | |
---|---|---|---|---|
All | 32.4 % (289 of 893) | 16.8 % (77 of 457) | 40.9 % (146 of 357) | 83.5 % (66 of 79) |
Backbone | 60.9 % (273 of 448) | 44.4 % (67 of 151) | 62.7 % (141 of 225) | 90.3 % (65 of 72) |
Sidechain | 16.4 % (85 of 518) | 3.3 % (10 of 306) | 36.1 % (74 of 205) | 14.3 % (1 of 7) |
Aromatic | 5.3 % (2 of 38) | 5.3 % (1 of 19) | 0.0 % (0 of 18) | 100.0 % (1 of 1) |
Methyl | 8.1 % (10 of 124) | 6.5 % (4 of 62) | 9.7 % (6 of 62) |
1. entity 1
AGHMTDTLFL TVTASLTLPW DHIQSTLLKT KGVTDIKIYP QKRTVAVTII PSIVNANQIK ELVPELSLDT GTLEKKSolvent system 95% H2O/5% D2O, Pressure 1 atm, Temperature 298 (±0.1) K, pH 7.4 (±0.02), Details 0.35 mM [U-13C; U-15N] HMA2A, 50 mM HEPES, 150 mM sodium chloride, 5 mM TCEP, 95% H2O/5% D2O
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | HMA2A | [U-13C; U-15N] | 0.35 (±0.02) mM | |
2 | HEPES | natural abundance | 50 (±1.0) mM | |
3 | sodium chloride | natural abundance | 150 (±1.0) mM | |
4 | TCEP | natural abundance | 5 (±0.2) mM |