Search

Intramembrane recognition between transmembrane domains of IL-9R and common gamma chain
Authors
Lenoir Capello, R., Cai, T., Chou, J.J.
Assembly
Cytokine receptor common subunit gamma, Interleukin-9 receptor
Entity
1. Cytokine receptor common subunit gamma, Interleukin-9 receptor, entity 1 (polymer, Thiol state: not present), 34 monomers, 3863.537 Da Detail

EENPSLFALE AVLIPVGTVG LIITLIFVYF WLER


2. Cytokine receptor common subunit gamma, Interleukin-9 receptor, entity 2 (polymer, Thiol state: not present), 31 monomers, 3536.339 Da Detail

QWSASILVVV PIFLLLTGFV HLLFKLSPRL K


Total weight
7399.876 Da
Max. entity weight
3863.537 Da
Source organism
Mus musculus
Exptl. method
solution NMR
Data set
assigned_chemical_shifts
Chemcal Shifts
1H: 379, 13C: 164, 15N: 53 assignments Detail
IDEntity IDSeq IDComp IDAtom IDAtom typeValVal errAmbig. code
114PROCC177.30.0301
214PROCAC62.890.0501
315SERHH8.310.0021
415SERHAH4.370.0101
515SERCC175.010.0301
615SERCAC58.660.0501
715SERNN115.830.0201
816LEUHH8.120.0021
916LEUHAH4.180.0101
1016LEUHB2H1.560.010
1116LEUHB3H1.560.010
1216LEUHD11H0.910.010
1316LEUHD12H0.910.010
1416LEUHD13H0.910.010
1516LEUHD21H0.840.010
1616LEUHD22H0.840.010
1716LEUHD23H0.840.010
1816LEUCC177.40.0301
1916LEUCAC55.570.0501
2016LEUCD1C24.540.020
2116LEUCD2C24.020.020
2216LEUNN123.610.0201
2317PHEHH7.940.0021
2417PHEHAH4.410.0101
2517PHEHB2H3.10.010
2617PHEHB3H3.10.010
2717PHEHD1H7.150.020
2817PHEHD2H7.150.020
2917PHEHE1H7.270.020
3017PHEHE2H7.270.020
3117PHECAC58.270.0501
3217PHENN118.510.0201
3318ALAHB1H1.450.0021
3418ALAHB2H1.450.0021
3518ALAHB3H1.450.0021
3618ALACBC18.60.0201
3719LEUCC178.650.0301
3819LEUCAC56.540.0501
39110GLUHH8.850.0021
40110GLUCC177.040.0301
41110GLUCAC59.050.0501
42110GLUNN118.930.0201
43111ALAHH7.910.0021
44111ALAHAH4.060.0101
45111ALAHB1H1.350.0101
46111ALAHB2H1.350.0101
47111ALAHB3H1.350.0101
48111ALACC177.210.0301
49111ALANN119.270.0201
50112VALHH7.260.0021
51112VALHAH4.040.0401
52112VALHG11H0.990.010
53112VALHG12H0.990.010
54112VALHG13H0.990.010
55112VALHG21H0.890.002
56112VALHG22H0.890.002
57112VALHG23H0.890.002
58112VALCAC62.440.0501
59112VALCG2C21.40.020
60112VALNN110.720.0201
61113LEUCC178.710.0301
62113LEUCAC57.150.0501
63114ILEHH8.370.0021
64114ILEHAH3.950.0101
65114ILEHBH1.780.0101
66114ILEHG21H0.80.0021
67114ILEHG22H0.80.0021
68114ILEHG23H0.80.0021
69114ILEHD11H0.860.0201
70114ILEHD12H0.860.0201
71114ILEHD13H0.860.0201
72114ILECAC65.720.0501
73114ILECG2C17.140.0201
74114ILECD1C12.770.0021
75114ILENN116.680.0201
76115PROHB2H2.170.010
77115PROHB3H2.170.010
78115PROHD2H3.740.010
79115PROHD3H3.740.010
80115PROCC177.610.0301
81116VALHH7.640.0021
82116VALHG11H1.010.005
83116VALHG12H1.010.005
84116VALHG13H1.010.005
85116VALCC177.70.0301
86116VALCAC66.130.0501
87116VALCG1C23.580.040
88116VALNN115.690.0201
89117GLYHH8.750.0021
90117GLYHA2H3.610.010
91117GLYHA3H3.610.010
92117GLYCC174.760.0301
93117GLYCAC46.30.0501
94117GLYNN107.60.0201
95118THRHH8.270.0021
96118THRHAH3.730.0101
97118THRHBH4.20.0101
98118THRHG21H1.080.0021
99118THRHG22H1.080.0021
100118THRHG23H1.080.0021
101118THRCC176.130.0301
102118THRCAC67.40.0501
103118THRCG2C21.030.0201
104118THRNN118.060.0201
105119VALHH80.0021
106119VALHAH3.50.0101
107119VALHBH2.20.0101
108119VALHG11H10.002
109119VALHG12H10.002
110119VALHG13H10.002
111119VALHG21H0.850.002
112119VALHG22H0.850.002
113119VALHG23H0.850.002
114119VALCC177.730.0301
115119VALCAC66.330.0501
116119VALCG1C23.230.020
117119VALCG2C21.450.020
118119VALNN120.580.0201
119120GLYHH8.540.0021
120120GLYHA2H3.590.010
121120GLYHA3H3.590.010
122120GLYCC175.730.0301
123120GLYCAC46.660.0501
124120GLYNN106.620.0201
125121LEUHH8.50.0021
126121LEUHAH4.020.0101
127121LEUHD11H0.820.002
128121LEUHD12H0.820.002
129121LEUHD13H0.820.002
130121LEUHD21H0.830.002
131121LEUHD22H0.830.002
132121LEUHD23H0.830.002
133121LEUCC177.670.0301
134121LEUCAC57.470.0501
135121LEUCD1C24.720.020
136121LEUCD2C23.990.020
137121LEUNN124.70.0201
138122ILEHH7.970.0021
139122ILEHAH3.530.0101
140122ILEHBH1.990.0101
141122ILEHG21H0.840.0021
142122ILEHG22H0.840.0021
143122ILEHG23H0.840.0021
144122ILEHD11H0.750.0021
145122ILEHD12H0.750.0021
146122ILEHD13H0.750.0021
147122ILECC177.30.0301
148122ILECAC650.0501
149122ILECG2C17.050.0201
150122ILECD1C13.110.0201
151122ILENN119.320.0201
152123ILEHH8.40.0021
153123ILEHAH3.590.0101
154123ILEHBH1.910.0101
155123ILEHG21H0.860.0021
156123ILEHG22H0.860.0021
157123ILEHG23H0.860.0021
158123ILEHD11H0.740.0021
159123ILEHD12H0.740.0021
160123ILEHD13H0.740.0021
161123ILECC177.150.0301
162123ILECAC64.640.0501
163123ILECG2C17.410.0201
164123ILECD1C13.240.0201
165123ILENN117.50.0201
166124THRHH7.940.0021
167124THRHAH3.720.0101
168124THRHBH4.330.0101
169124THRCC175.920.0301
170124THRCAC67.70.0501
171124THRNN116.450.0201
172125LEUHH8.230.0021
173125LEUHAH3.990.0101
174125LEUHB2H1.970.010
175125LEUHB3H1.970.010
176125LEUHD11H0.80.002
177125LEUHD12H0.80.002
178125LEUHD13H0.80.002
179125LEUHD21H0.80.002
180125LEUHD22H0.80.002
181125LEUHD23H0.80.002
182125LEUCC178.220.0301
183125LEUCAC57.440.0501
184125LEUCD1C25.330.020
185125LEUCD2C22.750.020
186125LEUNN120.170.0201
187126ILEHH80.0021
188126ILEHAH3.650.0101
189126ILEHBH2.040.0101
190126ILEHG21H0.940.0021
191126ILEHG22H0.940.0021
192126ILEHG23H0.940.0021
193126ILEHD11H0.770.0021
194126ILEHD12H0.770.0021
195126ILEHD13H0.770.0021
196126ILECC177.370.0301
197126ILECAC64.960.0501
198126ILECG2C17.690.0201
199126ILECD1C13.940.0201
200126ILENN118.80.0201
201127PHEHH8.330.0021
202127PHEHB2H3.210.010
203127PHEHB3H3.210.010
204127PHECC177.670.0301
205127PHECAC61.510.0501
206127PHENN118.760.0201
207128VALHH8.660.0021
208128VALHAH3.640.0101
209128VALHBH2.320.0101
210128VALHG11H1.160.002
211128VALHG12H1.160.002
212128VALHG13H1.160.002
213128VALHG21H1.010.002
214128VALHG22H1.010.002
215128VALHG23H1.010.002
216128VALCC176.910.0301
217128VALCAC66.250.0501
218128VALCG1C23.340.020
219128VALCG2C21.870.020
220128VALNN118.30.0201
221129TYRHH8.360.0021
222129TYRHAH3.950.0101
223129TYRHB2H2.940.010
224129TYRHB3H3.120.010
225129TYRHD1H6.440.010
226129TYRHD2H6.440.010
227129TYRCC176.90.0301
228129TYRCAC61.510.0501
229129TYRNN119.320.0201
230130PHEHH8.050.0021
231130PHEHAH4.140.0101
232130PHEHB2H2.970.010
233130PHEHB3H3.10.010
234130PHECC177.330.0301
235130PHECAC60.380.0501
236130PHENN115.030.0201
237131TRPHH8.490.0021
238131TRPHAH4.290.0101
239131TRPHB2H3.070.010
240131TRPHB3H3.350.010
241131TRPHE1H10.250.0101
242131TRPCC177.210.0301
243131TRPCAC59.050.0501
244131TRPNN120.780.0201
245132LEUHH7.920.0021
246132LEUHAH3.960.0101
247132LEUHB2H1.770.010
248132LEUHB3H1.930.010
249132LEUHGH1.480.0101
250132LEUHD11H0.860.002
251132LEUHD12H0.860.002
252132LEUHD13H0.860.002
253132LEUHD21H0.790.002
254132LEUHD22H0.790.002
255132LEUHD23H0.790.002
256132LEUCC177.510.0301
257132LEUCD1C25.690.020
258132LEUCD2C23.250.020
259132LEUNN117.680.0201
260133GLUHH7.710.0021
261133GLUHAH4.140.0101
262133GLUHB2H1.660.010
263133GLUHB3H1.660.010
264133GLUHG2H1.980.010
265133GLUHG3H1.980.010
266133GLUCC175.30.0301
267133GLUCAC55.30.0501
268133GLUNN119.790.0201
269134ARGHH7.440.0021
270134ARGHAH40.0101
271134ARGHB2H1.730.010
272134ARGHB3H1.730.010
273134ARGHG2H1.610.010
274134ARGHG3H1.610.010
275134ARGHD2H2.960.010
276134ARGHD3H2.960.010
277134ARGCAC56.530.0501
278134ARGNN126.660.0201
27922TRPHE1H10.330.0101
28022TRPCC176.390.0301
28122TRPCAC56.530.0501
28223SERHH8.180.0021
28323SERHAH4.360.0301
28423SERCC174.860.0301
28523SERCAC57.470.0501
28623SERNN116.50.0201
28724ALAHH8.490.0021
28824ALAHAH4.140.0201
28924ALAHB1H1.420.0201
29024ALAHB2H1.420.0201
29124ALAHB3H1.420.0201
29224ALACC178.310.0301
29324ALACAC53.280.0501
29424ALACBC18.690.0201
29524ALANN1250.0201
29625SERHH8.050.0021
29725SERHAH4.160.0201
29825SERCC176.120.0301
29925SERCAC60.280.0501
30025SERNN112.890.0201
30126ILEHH7.940.0021
30226ILEHAH3.880.0201
30326ILEHBH20.0201
30426ILEHG12H1.290.020
30526ILEHG13H1.590.020
30626ILEHG21H0.920.0101
30726ILEHG22H0.920.0101
30826ILEHG23H0.920.0101
30926ILEHD11H0.850.0101
31026ILEHD12H0.850.0101
31126ILEHD13H0.850.0101
31226ILECC176.240.0301
31326ILECAC62.560.0501
31426ILECG2C18.070.0201
31526ILECD1C13.470.0201
31626ILENN1220.0201
31727LEUHH7.770.0021
31827LEUHAH3.940.0201
31927LEUHB2H1.860.020
32027LEUHB3H1.860.020
32127LEUHGH1.510.0201
32227LEUHD11H0.950.020
32327LEUHD12H0.950.020
32427LEUHD13H0.950.020
32527LEUHD21H0.830.050
32627LEUHD22H0.830.050
32727LEUHD23H0.830.050
32827LEUCC176.430.0301
32927LEUCAC56.240.0501
33027LEUCD1C25.550.030
33127LEUCD2C23.240.050
33227LEUNN118.210.0201
33328VALHH7.420.0021
33428VALHAH3.930.0201
33528VALHBH2.190.0201
33628VALHG11H0.940.010
33728VALHG12H0.940.010
33828VALHG13H0.940.010
33928VALHG21H1.030.010
34028VALHG22H1.030.010
34128VALHG23H1.030.010
34228VALCC176.510.0301
34328VALCAC63.330.0501
34428VALCG1C21.560.020
34528VALCG2C22.120.020
34628VALNN113.230.0201
34729VALHH7.940.0021
34829VALHAH3.660.0201
34929VALHBH2.120.0201
35029VALHG11H0.890.010
35129VALHG12H0.890.010
35229VALHG13H0.890.010
35329VALHG21H1.020.010
35429VALHG22H1.020.010
35529VALHG23H1.020.010
35629VALCC177.290.0301
35729VALCAC64.990.0501
35829VALCG1C21.620.020
35929VALCG2C22.420.020
36029VALNN116.240.0201
361210VALHH8.020.0021
362210VALHAH3.790.0201
363210VALHBH2.40.0201
364210VALHG11H0.870.010
365210VALHG12H0.870.010
366210VALHG13H0.870.010
367210VALHG21H1.040.010
368210VALHG22H1.040.010
369210VALHG23H1.040.010
370210VALCAC68.270.0501
371210VALCG1C21.270.020
372210VALCG2C24.140.020
373210VALNN117.790.0201
374211PROHAH4.140.0201
375211PROCC177.570.0301
376211PROCAC65.410.0501
377212ILEHH7.120.0021
378212ILEHAH3.620.0201
379212ILEHBH1.970.0201
380212ILEHG12H1.020.020
381212ILEHG13H1.020.020
382212ILEHG21H0.80.0101
383212ILEHG22H0.80.0101
384212ILEHG23H0.80.0101
385212ILEHD11H0.770.0101
386212ILEHD12H0.770.0101
387212ILEHD13H0.770.0101
388212ILECC176.90.0301
389212ILECAC64.90.0501
390212ILECG2C17.20.0101
391212ILECD1C13.080.0201
392212ILENN115.550.0201
393213PHEHH8.580.0021
394213PHEHAH4.110.0301
395213PHEHB2H3.20.020
396213PHEHB3H3.20.020
397213PHEHD1H7.050.020
398213PHEHD2H7.050.020
399213PHECC178.710.0301
400213PHECAC60.920.0501
401213PHENN120.020.0201
402214LEUHH8.430.0021
403214LEUHAH3.90.0201
404214LEUHB2H1.920.020
405214LEUHB3H1.920.020
406214LEUHGH1.370.0201
407214LEUHD11H0.810.010
408214LEUHD12H0.810.010
409214LEUHD13H0.810.010
410214LEUHD21H0.790.010
411214LEUHD22H0.790.010
412214LEUHD23H0.790.010
413214LEUCC178.080.0301
414214LEUCAC57.240.0501
415214LEUCD1C25.830.020
416214LEUCD2C22.790.020
417214LEUNN120.790.0201
418215LEUHH8.160.0021
419215LEUHAH3.940.0201
420215LEUHB2H1.730.020
421215LEUHB3H1.730.020
422215LEUHGH1.550.0201
423215LEUCC178.390.0301
424215LEUCAC57.360.0501
425215LEUCD1C24.890.020
426215LEUCD2C24.350.020
427215LEUNN120.020.0201
428216LEUHH8.280.0021
429216LEUHAH4.020.0201
430216LEUHB2H1.770.020
431216LEUHB3H1.770.020
432216LEUHGH1.50.0201
433216LEUHD11H0.780.020
434216LEUHD12H0.780.020
435216LEUHD13H0.780.020
436216LEUHD21H0.750.020
437216LEUHD22H0.750.020
438216LEUHD23H0.750.020
439216LEUCC178.350.0301
440216LEUCAC57.440.0501
441216LEUCD1C25.080.020
442216LEUCD2C23.650.020
443216LEUNN118.040.0201
444217THRHH80.0021
445217THRHAH3.670.0201
446217THRHBH4.040.0201
447217THRHG21H0.980.0201
448217THRHG22H0.980.0201
449217THRHG23H0.980.0201
450217THRCC176.710.0301
451217THRCAC66.890.0501
452217THRCG2C21.740.0301
453217THRNN114.950.0201
454218GLYHH8.280.0021
455218GLYHA2H3.560.030
456218GLYHA3H3.690.030
457218GLYCC174.590.0301
458218GLYCAC46.710.0501
459218GLYNN108.930.0201
460219PHEHH8.470.0021
461219PHEHAH4.250.0201
462219PHEHB2H3.210.040
463219PHEHB3H3.210.040
464219PHEHD1H6.970.020
465219PHEHD2H6.970.020
466219PHEHE1H7.070.020
467219PHEHE2H7.070.020
468219PHECC176.590.0301
469219PHECAC60.260.0501
470219PHENN121.570.0201
471220VALHH8.270.0021
472220VALHAH3.360.0201
473220VALHBH2.180.0201
474220VALHG11H0.860.010
475220VALHG12H0.860.010
476220VALHG13H0.860.010
477220VALHG21H1.070.010
478220VALHG22H1.070.010
479220VALHG23H1.070.010
480220VALCC177.060.0301
481220VALCAC66.330.0501
482220VALCG1C22.310.020
483220VALCG2C23.470.020
484220VALNN118.640.0201
485221HISHH8.190.0021
486221HISHAH4.270.0201
487221HISHB2H3.090.020
488221HISHB3H3.090.020
489221HISCC177.610.0301
490221HISCAC59.490.0501
491221HISNN118.990.0201
492222LEUHH8.030.0021
493222LEUHAH3.870.0201
494222LEUHB2H1.760.020
495222LEUHB3H1.760.020
496222LEUHD11H0.880.010
497222LEUHD12H0.880.010
498222LEUHD13H0.880.010
499222LEUHD21H0.850.010
500222LEUHD22H0.850.010
501222LEUHD23H0.850.010
502222LEUCC178.390.0301
503222LEUCAC57.160.0501
504222LEUCD1C250.020
505222LEUCD2C24.490.020
506222LEUNN118.730.0201
507223LEUHH8.020.0021
508223LEUHAH3.780.0201
509223LEUHB2H1.620.030
510223LEUHB3H1.620.030
511223LEUHD11H0.590.010
512223LEUHD12H0.590.010
513223LEUHD13H0.590.010
514223LEUHD21H0.60.010
515223LEUHD22H0.60.010
516223LEUHD23H0.60.010
517223LEUCC179.020.0301
518223LEUCAC57.160.0501
519223LEUCD1C25.060.020
520223LEUCD2C23.480.020
521223LEUNN118.730.0201
522224PHEHH8.020.0021
523224PHEHAH4.210.0201
524224PHEHB2H3.140.020
525224PHEHB3H3.140.020
526224PHEHD1H6.750.050
527224PHEHD2H6.750.050
528224PHECC178.120.0301
529224PHECAC59.840.0501
530224PHENN117.010.0201
531225LYSHH7.940.0021
532225LYSHAH4.050.0201
533225LYSHB2H1.780.020
534225LYSHB3H1.840.020
535225LYSCC177.960.0301
536225LYSCAC56.610.0501
537225LYSNN119.160.0201
538226LEUHH7.850.0021
539226LEUHAH4.260.0201
540226LEUHB2H1.780.020
541226LEUHB3H1.780.020
542226LEUHGH1.540.0201
543226LEUHD11H0.810.010
544226LEUHD12H0.810.010
545226LEUHD13H0.810.010
546226LEUHD21H0.820.010
547226LEUHD22H0.820.010
548226LEUHD23H0.820.010
549226LEUCC177.060.0301
550226LEUCAC54.590.0501
551226LEUCD1C25.620.020
552226LEUCD2C23.070.020
553226LEUNN117.870.0201
554227SERHH7.60.0021
555227SERHAH3.850.0301
556227SERHB2H4.370.030
557227SERHB3H4.370.030
558227SERCAC58.030.0501
559227SERNN115.210.0201
560228PROHAH4.40.0201
561228PROHB2H2.20.020
562228PROHB3H2.20.020
563228PROHG2H1.940.030
564228PROHG3H1.940.030
565228PROHD2H3.590.020
566228PROHD3H3.780.020
567228PROCC176.980.0301
568228PROCAC63.10.0501
569229ARGHH8.080.0021
570229ARGHAH4.30.0201
571229ARGHB2H1.880.020
572229ARGHB3H1.880.020
573229ARGHD2H3.170.030
574229ARGHD3H3.170.030
575229ARGCC176.310.0301
576229ARGCAC55.030.0501
577229ARGNN118.470.0201
578230LEUHH80.0021
579230LEUHAH4.320.0201
580230LEUHB2H1.620.030
581230LEUHB3H1.620.030
582230LEUHD11H0.850.010
583230LEUHD12H0.850.010
584230LEUHD13H0.850.010
585230LEUHD21H0.810.020
586230LEUHD22H0.810.020
587230LEUHD23H0.810.020
588230LEUCC175.880.0301
589230LEUCAC54.320.0501
590230LEUCD1C25.330.020
591230LEUCD2C23.290.020
592230LEUNN122.510.0201
593231LYSHH7.50.0021
594231LYSHAH4.080.0201
595231LYSCAC56.730.0501
596231LYSNN125.610.0201

Release date
2022-06-29
Citation
Structural basis of γ -chain family receptor sharing at the membrane level
Cai, T., Lenoir Capello, R., Pi, X., Wu, H., Chou, J.J.
bioRxiv. (2023), PubMed 37205582 , DOI 10.1101/2023.05.05.539662 ,
Entries sharing articles BMRB: 1 entries Detail
  BMRB: 31026 released on 2022-07-17
    Title Intramembrane recognition between transmembrane domains of IL-7R and common gamma chain
Related entities 1. Cytokine receptor common subunit gamma, Interleukin-9 receptor, entity 1, : 1 : 1 : 11 entities Detail
Related entities 2. Cytokine receptor common subunit gamma, Interleukin-9 receptor, entity 2, : 1 : 2 : 3 entities Detail
Interaction partners 1. Cytokine receptor common subunit gamma, Interleukin-9 receptor, entity 1, : 3 interactors Detail
Experiments performed 21 experiments Detail
nullKeywords MEMBRANE PROTEIN, common gamma-chain cytokine receptor, receptor sharing, transmembrane domain