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BMRB: 31074


31074
7QK3
Temperature-dependent structures of tau aggregates
Authors
El Mammeri, N., Duan, P., Dregni, A.J., Hong, M.
Assembly
Microtubule-associated protein tau
Entity
1. Microtubule-associated protein tau (polymer), 202 monomers, 21409.27 × 5 Da Detail

SSPGSPGTPG SRSRTPSLPT PPTREPKKVA VVRTPPKSPS SAKSRLQTAP VPMPDLKNVK SKIGSTENLK HQPGGGKVQI INKKLDLSNV QSKCGSKDNI KHVPGGGSVQ IVYKPVDLSK VTSKCGSLGN IHHKPGGGQV EVKSEKLDFK DRVQSKIGSL DNITHVPGGG NKKIETHKLT FRENAKAKTD HGAEIVYKSP VV


Total weight
107046.34 Da
Max. entity weight
21409.27 Da
Source organism
Homo sapiens
Exptl. method
solid-state NMR
Data set
assigned_chemical_shifts
Chemcal Shifts
13C: 176, 15N: 47 assignments Detail
Download
IDEntity IDSeq IDComp IDAtom IDAtom typeValVal errAmbig. code
1179GLNCBC31.659
2179GLNCGC32.826
3179GLNCDC177.483
4179GLNNN129.856
5180ILECC171.612
6180ILECAC57.688
7180ILECBC40.08
8180ILECG1C25.948
9180ILECG2C15.749
10180ILECD1C13.907
11180ILENN126.721
12181ILECC171.134
13181ILECAC57.473
14181ILECBC38.534
15181ILECG1C25.848
16181ILECG2C15.577
17181ILECD1C10.71
18181ILENN127.261
19182ASNCC170.534
20182ASNCAC50.091
21182ASNCBC38.754
22182ASNCGC174.155
23182ASNNN127.136
24182ASNND2N116.74
25183LYSCC173.024
26183LYSCAC52.058
27183LYSCBC35.439
28183LYSCGC24.044
29183LYSCDC28.128
30183LYSNN123.178
31184LYSCC172.876
32184LYSCAC55.342
33184LYSCBC33.668
34184LYSCGC24.456
35184LYSCDC27.217
36184LYSNN124.027
37185LEUCC173.355
38185LEUCAC51.668
39185LEUCBC41.748
40185LEUCGC27.013
41185LEUCD2C23.487
42185LEUNN122.408
43186ASPCC174.134
44186ASPCAC50.753
45186ASPCBC42.553
46186ASPCGC177.688
47186ASPNN123.586
48187LEUCC172.43
49187LEUCAC53.991
50187LEUCBC39.035
51187LEUCGC25.368
52187LEUCD1C23.544
53187LEUCD2C23.635
54187LEUNN127.285
55188SERCC168.644
56188SERCAC57.16
57188SERCBC65.985
58188SERNN107.104
59189ASNCC170.626
60189ASNCAC50.262
61189ASNCBC40.05
62189ASNCGC173.801
63189ASNNN125.649
64189ASNND2N117.137
65190VALCC172.244
66190VALCAC58.219
67190VALCBC34.498
68190VALCG1C20.731
69190VALCG2C18.777
70190VALNN125.285
71191GLNCC174.881
72191GLNCAC54.153
73191GLNCBC31.15
74191GLNCGC34.575
75191GLNCDC178.048
76191GLNNN124.143
77191GLNNE2N116.976
78192SERCC171.637
79192SERCAC54.279
80192SERCBC63.842
81192SERNN115.252
82193LYSCC173
83193LYSCAC53.385
84193LYSCBC30.484
85193LYSCGC26.106
86193LYSNN129.928
87194CYSCC172.13
88194CYSCAC56.693
89194CYSCBC28.633
90194CYSNN115.192
91195GLYCC170.82
92195GLYCAC42.949
93195GLYNN113.294
94196SERCC172.026
95196SERCAC54.555
96196SERCBC64.745
97196SERNN118.101
98197LYSCC172.621
99197LYSCAC54.234
100197LYSCBC32.714
101197LYSCGC23.863
102197LYSCDC28.082
103197LYSNN124.679
104198ASPCC171.72
105198ASPCAC51.461
106198ASPCBC43.357
107198ASPCGC181.488
108198ASPNN126.815
109199ASNCC171.687
110199ASNCAC50.717
111199ASNCBC41.618
112199ASNCGC174.881
113199ASNNN121.006
1141100ILECAC58.654
1151100ILECBC38.994
1161100ILECG1C24.797
1171100ILECG2C15.635
1181100ILECD1C11.949
1191100ILENN122.068
1201103VALCC172.244
1211103VALCAC57.882
1221103VALCBC30.499
1231103VALNN120.786
1241104PROCC173.448
1251104PROCAC61.563
1261104PROCBC30.567
1271104PROCGC25.969
1281104PROCDC48.998
1291104PRONN134.403
1301105GLYCC170.134
1311105GLYCAC43.636
1321105GLYNN105.772
1331106GLYCC173.099
1341106GLYCAC43.376
1351106GLYNN108.578
1361107GLYCAC42.028
1371107GLYNN112.113
1381108SERNN114.596
1391109VALCBC31.537
1401110GLNCC172.377
1411110GLNCAC51.986
1421110GLNCBC33.815
1431110GLNCGC32.783
1441110GLNCDC178.566
1451110GLNNN126.864
1461111ILECC172.251
1471111ILECAC57.79
1481111ILECBC41.824
1491111ILECG1C25.71
1501111ILECG2C15.263
1511111ILECD1C11.93
1521111ILENN122.47
1531112VALCC172.223
1541112VALCAC59.903
1551112VALCBC31.96
1561112VALCG1C20.582
1571112VALCG2C20.547
1581112VALNN128.244
1591113TYRCC170.026
1601113TYRCAC55.903
1611113TYRCBC40.827
1621113TYRCGC130.502
1631113TYRCZC157.547
1641113TYRNN130.588
1651114LYSCC169.024
1661114LYSCAC55.637
1671114LYSCBC31.207
1681114LYSCGC25.401
1691114LYSCDC30.108
1701114LYSCEC40.931
1711114LYSNN128.517
1721115PROCC174.514
1731115PROCAC61.359
1741115PROCBC30.407
1751115PROCGC26.511
1761115PROCDC47.851
1771115PRONN131.492
1781116VALCC172.377
1791116VALCAC60.62
1801116VALCBC33.589
1811116VALCG1C19.66
1821116VALCG2C18.83
1831116VALNN122.958
1841117ASPCC171.487
1851117ASPCAC51.688
1861117ASPCBC41.774
1871117ASPCGC179.908
1881117ASPNN130.651
1891118LEUCC175.137
1901118LEUCAC51.149
1911118LEUCBC40.235
1921118LEUCGC25.121
1931118LEUCD1C24.32
1941118LEUCD2C23.2
1951118LEUNN122.061
1961119SERCC170.718
1971119SERCAC55.423
1981119SERCBC65.861
1991119SERNN117.776
2001120LYSCC173.129
2011120LYSCAC53.285
2021120LYSCBC36.535
2031120LYSCGC28.635
2041120LYSCDC23.958
2051120LYSCEC39.972
2061120LYSNN121.787
2071121VALCC173.552
2081121VALCAC59.316
2091121VALCBC33.412
2101121VALCG1C19.377
2111121VALNN128.325
2121122THRCC171.467
2131122THRCAC59.349
2141122THRCBC69.219
2151122THRNN124.708
2161123SERCC171.983
2171123SERCAC55.026
2181123SERCBC63.014
2191123SERNN120.976
2201172LYSCC173.583
2211173LYSCC171.766
2221173LYSNN118.991
2231174ILENN119.925

Release date
2023-02-22
Citation
Influence of Fibril Growth Rates on the Structure of Tau Aggregates
El Mammeri, N., Duan, P., Dregni, A.J., Hong, M.
Related entities 1. Microtubule-associated protein tau, : 1 : 104 : 3 : 2 : 21 entities Detail
More details for 131 related entities
Interaction partners 1. Microtubule-associated protein tau, : 50 interactors Detail
More details for 50 interactors identified by 27 citations
Experiments performed 5 experiments Detail
Chemical shift validation 3 contents Detail
Keywords PROTEIN FIBRIL, amyloid fibril, tau