BMRB: 34502

LNA modified G-quadruplex with flipped G-tract and central tetrad

Authors

Weisz, K., Haase, L.

Assembly

DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GF2))-R(P*(LCG))-D(P*GP*GP*AP*CP*GP*GP*G)-3')

Entity

1. DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GF2))-R(P*(LCG))-D(P*GP*GP*AP*CP*GP*GP*G)-3') (polymer, Thiol state: not present), 22 monomers, 7063.471 Da Detail

GGGATGGGAC ACAGXGGACG GG

Formula weight

7063.471 Da

Source organism

synthetic construct

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chemcal Shifts

¹H: 125, ¹³C: 24 assignments Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

ID	Entity ID	Seq ID	Comp ID	Atom ID	Atom type	Val	Val err	Ambig. code
1	1	1	DG	H1	H	11.725	0.002	1
2	1	1	DG	H1'	H	6.106	0.001	1
3	1	1	DG	H2'	H	2.671	0.005	1
4	1	1	DG	H2''	H	3.204	0.003	1
5	1	1	DG	H3'	H	5.018	0.003	1
6	1	1	DG	H8	H	7.370	0.002	1
7	1	1	DG	C8	C	141.070		1
8	1	2	DG	H1	H	11.729	0.001	1
9	1	2	DG	H1'	H	5.871	0.004	1
10	1	2	DG	H2'	H	2.504	0.002	1
11	1	2	DG	H2''	H	2.684	0.004	1
12	1	2	DG	H3'	H	5.122	0.0	1
13	1	2	DG	H8	H	7.894	0.002	1
14	1	2	DG	C8	C	138.350		1
15	1	3	DG	H1	H	11.437	0.004	1
16	1	3	DG	H1'	H	6.285	0.001	1
17	1	3	DG	H2'	H	2.837	0.003	1
18	1	3	DG	H2''	H	2.572	0.002	1
19	1	3	DG	H3'	H	5.009	0.004	1
20	1	3	DG	H8	H	7.943	0.002	1
21	1	3	DG	C8	C	137.018		1
22	1	4	DA	H1'	H	6.390	0.001	1
23	1	4	DA	H2	H	7.293	0.002	1
24	1	4	DA	H2'	H	2.673	0.004	2
25	1	4	DA	H2''	H	2.642	0.002	2
26	1	4	DA	H3'	H	5.028	0.003	1
27	1	4	DA	H8	H	8.303	0.001	1
28	1	4	DA	C2	C	154.536		1
29	1	4	DA	C8	C	142.189		1
30	1	5	DT	H1'	H	6.001	0.005	1
31	1	5	DT	H2'	H	2.071	0.001	1
32	1	5	DT	H2''	H	2.598	0.001	1
33	1	5	DT	H3'	H	4.874	0.002	1
34	1	5	DT	H6	H	7.204	0.001	1
35	1	5	DT	H71	H	1.114	0.002	1
36	1	5	DT	H72	H	1.114	0.002	1
37	1	5	DT	H73	H	1.114	0.002	1
38	1	5	DT	C6	C	137.918		1
39	1	6	DG	H1	H	11.432	0.002	1
40	1	6	DG	H1'	H	6.138	0.002	1
41	1	6	DG	H2'	H	3.631	0.004	1
42	1	6	DG	H2''	H	3.179	0.005	1
43	1	6	DG	H3'	H	4.860	0.003	1
44	1	6	DG	H8	H	7.314	0.002	1
45	1	6	DG	C8	C	141.614		1
46	1	7	DG	H1	H	11.269	0.002	1
47	1	7	DG	H1'	H	5.755	0.004	1
48	1	7	DG	H2'	H	2.651	0.004	1
49	1	7	DG	H2''	H	2.476	0.001	1
50	1	7	DG	H3'	H	5.003	0.003	1
51	1	7	DG	H8	H	7.237	0.001	1
52	1	7	DG	C8	C	140.380		1
53	1	8	DG	H1	H	11.232	0.004	1
54	1	8	DG	H1'	H	5.804	0.002	1
55	1	8	DG	H2'	H	2.083	0.001	1
56	1	8	DG	H2''	H	2.375	0.001	1
57	1	8	DG	H3'	H	4.931	0.001	1
58	1	8	DG	H8	H	7.581	0.002	1
59	1	8	DG	C8	C	137.690		1
60	1	9	DA	H1'	H	5.925	0.003	1
61	1	9	DA	H2'	H	2.675	0.004	1
62	1	9	DA	H2''	H	2.547	0.012	1
63	1	9	DA	H3'	H	4.943	0.002	1
64	1	9	DA	H8	H	8.012	0.001	1
65	1	9	DA	C8	C	141.706		1
66	1	10	DC	H1'	H	5.885	0.003	1
67	1	10	DC	H2'	H	1.779	0.004	1
68	1	10	DC	H2''	H	2.159	0.002	1
69	1	10	DC	H3'	H	4.591	0.001	1
70	1	10	DC	H5	H	5.890	0.0	1
71	1	10	DC	H6	H	7.619	0.012	1
72	1	10	DC	C6	C	143.721		1
73	1	11	DA	H1'	H	5.697	0.001	1
74	1	11	DA	H2'	H	2.342	0.001	1
75	1	11	DA	H2''	H	1.864	0.003	1
76	1	11	DA	H3'	H	4.351	0.002	1
77	1	11	DA	H8	H	7.838	0.001	1
78	1	11	DA	C8	C	141.435		1
79	1	12	DC	H1'	H	5.581	0.002	1
80	1	12	DC	H2'	H	1.649	0.002	1
81	1	12	DC	H2''	H	1.976	0.002	1
82	1	12	DC	H3'	H	4.395	0.003	1
83	1	12	DC	H5	H	5.109	0.004	1
84	1	12	DC	H6	H	7.047	0.001	1
85	1	12	DC	C6	C	143.471		1
86	1	13	DA	H1'	H	6.191	0.001	1
87	1	13	DA	H2	H	7.647	0.002	1
88	1	13	DA	H2'	H	2.517	0.002	1
89	1	13	DA	H2''	H	2.275	0.001	1
90	1	13	DA	H3'	H	4.666	0.002	1
91	1	13	DA	H8	H	7.923	0.002	1
92	1	13	DA	C2	C	154.444		1
93	1	13	DA	C8	C	141.647		1
94	1	14	DG	H1	H	11.171	0.003	1
95	1	14	DG	H1'	H	6.003	0.004	1
96	1	14	DG	H2'	H	3.615	0.001	1
97	1	14	DG	H2''	H	2.865	0.001	1
98	1	14	DG	H3'	H	4.943	0.003	1
99	1	14	DG	H8	H	7.392	0.002	1
100	1	14	DG	C8	C	141.283		1
101	1	15	LCG	H1	H	11.773	0.002	1
102	1	15	LCG	H1'	H	5.526	0.002	1
103	1	15	LCG	H2'	H	4.664	0.001	1
104	1	15	LCG	H3'	H	4.342	0.002	1
105	1	15	LCG	H8	H	7.483	0.002	1
106	1	15	LCG	C8	C	137.196		1
107	1	16	DG	H1	H	11.508	0.005	1
108	1	16	DG	H1'	H	6.028	0.003	1
109	1	16	DG	H2'	H	1.335	0.002	1
110	1	16	DG	H2''	H	2.499	0.002	1
111	1	16	DG	H3'	H	4.789	0.002	1
112	1	16	DG	H8	H	7.405	0.002	1
113	1	16	DG	C8	C	136.789		1
114	1	17	DG	H1'	H	6.033	0.001	1
115	1	17	DG	H2'	H	2.640	0.004	1
116	1	17	DG	H2''	H	2.385	0.001	1
117	1	17	DG	H8	H	7.915	0.002	1
118	1	17	DG	C8	C	138.457		1
119	1	18	DA	H1'	H	5.896	0.001	1
120	1	18	DA	H2'	H	2.420	0.002	1
121	1	18	DA	H2''	H	2.286	0.001	1
122	1	18	DA	H8	H	8.059	0.002	1
123	1	18	DA	C8	C	142.307		1
124	1	19	DC	H2'	H	1.874		2
125	1	19	DC	H2''	H	2.398	0.001	2
126	1	19	DC	H5	H	5.775	0.0	1
127	1	19	DC	H6	H	7.379	0.004	1
128	1	19	DC	C6	C	143.145		1
129	1	20	DG	H1	H	11.612	0.001	1
130	1	20	DG	H1'	H	6.067	0.001	1
131	1	20	DG	H2'	H	3.198	0.002	2
132	1	20	DG	H2''	H	3.727	0.002	2
133	1	20	DG	H3'	H	4.824	0.001	1
134	1	20	DG	H8	H	7.138	0.002	1
135	1	20	DG	C8	C	141.304		1
136	1	21	DG	H1	H	11.488	0.002	1
137	1	21	DG	H1'	H	5.743	0.002	1
138	1	21	DG	H2'	H	2.506	0.005	2
139	1	21	DG	H2''	H	2.566	0.003	2
140	1	21	DG	H3'	H	5.039	0.004	1
141	1	21	DG	H8	H	7.370	0.003	1
142	1	21	DG	C8	C	140.892		1
143	1	22	DG	H1	H	11.654	0.004	1
144	1	22	DG	H1'	H	5.936	0.003	1
145	1	22	DG	H2'	H	2.472	0.002	1
146	1	22	DG	H2''	H	2.805	0.003	1
147	1	22	DG	H3'	H	4.730	0.001	1
148	1	22	DG	H8	H	7.924	0.003	1
149	1	22	DG	C8	C	138.659		1

Release date

2020-07-13

Citation

Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design
Haase, L., Weisz, K.
Nucleic Acids Res. (2020), 48, 10555-10566, PubMed 32890406 , DOI 10.1093/nar/gkaa720 , Abstract

Experiments performed 5 experiments Detail

Chemical shift validation 3 contents Detail