Search

Parallel Q-D hybrid with 3' duplex stem-loop as a lateral snapback loop
Authors
Vianney, Y.M., Weisz, K.
Assembly
TTAMycdup-3sbl
Entity
1. TTAMycdup-3sbl (polymer, Thiol state: not present), 36 monomers, 11273.22 Da Detail

XTAGGTGGGT AGGGTGGGCT AGTCATTTTG ACTAGG


Formula weight
11273.22 Da
Source organism
synthetic construct
Exptl. method
solution NMR
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 97.2 %, Completeness: 66.3 %, Completeness (bb): 57.1 % Detail

Polymer type: polydeoxyribonucleotide

Total1H
All66.3 % (220 of 332)66.3 % (220 of 332)
Suger, PO457.1 % (140 of 245)57.1 % (140 of 245)
Nucleobase92.0 % (80 of 87)92.0 % (80 of 87)
Aromatic90.0 % (63 of 70)90.0 % (63 of 70)
Methyl100.0 % (11 of 11)100.0 % (11 of 11)

1. entity 1

XTAGGTGGGT AGGGTGGGCT AGTCATTTTG ACTAGG

Sample

Solvent system 90% H2O/10% D2O, Pressure 1 atm, Temperature 293 K, pH 7.0, Details 1 mM 0 DNA, 90% H2O/10% D2O


#NameIsotope labelingTypeConcentration
1DNAnatural abundance1 mM
2potassium phosphate buffernatural abundance10 mM

Release date
2021-09-08
Citation
Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces
Vianney, Y.M., Weisz, K.
Chemistry (2022), 28, e202103718-e202103718, PubMed 34905232 , DOI 10.1002/chem.202103718 ,
Entries sharing articles BMRB: 1 entries Detail
  BMRB: 34665 released on 2021-09-08
    Title Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid
Experiments performed 3 experiments Detail
Chemical shift validation 3 contents Detail
Keywords DNA, G-quadruplex, Quadruplex-duplex junction, duplex