BMRB: 34725

RNA binding induces an allosteric switch in Cyp33 to repress MLL1 mediated transcription regulation

Authors

Blatter, M., Allain, F., Meylan, C.

Assembly

Peptidyl-prolyl cis-trans isomerase E/RNA Complex

Entity

1. Peptidyl-prolyl cis-trans isomerase E/RNA Complex, entity 1 (polymer, Thiol state: not present), 117 monomers, 13171.70 Da Detail

AGHMATTKRV LYVGGLAEEV DDKVLHAAFI PFGDITDIQI PLDYETEKHR GFAFVEFELA EDAAAAIDNM NESELFGRTI RVNLAKPMRI KEGSSRPVWS DDDWLKKFSG KTLEENK

2. Peptidyl-prolyl cis-trans isomerase E/RNA Complex, entity 2 (polymer, Thiol state: not present), 6 monomers, 1970.210 Da Detail

AAUAAA

Total weight

15141.91 Da

Max. entity weight

13171.7 Da

Source organism

Homo sapiens

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chemcal Shifts

¹H: 855, ¹³C: 430, ¹⁵N: 113 assignments Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

ID	Entity ID	Seq ID	Comp ID	Atom ID	Atom type	Val	Val err	Ambig. code
1	1	1	ALA	HA	H	4.031	0.000
2	1	1	ALA	HB1	H	1.466	0.000
3	1	1	ALA	HB2	H	1.466	0.000
4	1	1	ALA	HB3	H	1.466	0.000
5	1	1	ALA	CA	C	52.072	0.000
6	1	1	ALA	CB	C	19.748	0.000
7	1	2	GLY	HA2	H	3.936	0.000
8	1	2	GLY	HA3	H	3.936	0.000
9	1	2	GLY	CA	C	45.218	0.000
10	1	3	HIS	HB2	H	3.066	0.000
11	1	3	HIS	HB3	H	3.019	0.000
12	1	3	HIS	HD2	H	6.997	0.000
13	1	3	HIS	HE1	H	7.875	0.000
14	1	3	HIS	CB	C	30.941	0.009
15	1	3	HIS	CD2	C	119.882	0.000
16	1	3	HIS	CE1	C	138.323	0.000
17	1	4	MET	HA	H	4.427	0.000
18	1	4	MET	HB2	H	2.480	0.000
19	1	4	MET	HB3	H	2.402	0.000
20	1	4	MET	HG2	H	2.005	0.000
21	1	4	MET	HG3	H	1.930	0.000
22	1	4	MET	HE1	H	2.012	0.000
23	1	4	MET	HE2	H	2.012	0.000
24	1	4	MET	HE3	H	2.012	0.000
25	1	4	MET	CA	C	55.499	0.000
26	1	4	MET	CB	C	32.029	0.005
27	1	4	MET	CG	C	33.161	0.006
28	1	4	MET	CE	C	17.041	0.000
29	1	5	ALA	H	H	8.452	0.000
30	1	5	ALA	HA	H	4.374	0.000
31	1	5	ALA	HB1	H	1.394	0.000
32	1	5	ALA	HB2	H	1.394	0.000
33	1	5	ALA	HB3	H	1.394	0.000
34	1	5	ALA	CA	C	52.730	0.000
35	1	5	ALA	CB	C	19.432	0.000
36	1	5	ALA	N	N	125.355	0.000
37	1	6	THR	H	H	8.164	0.000
38	1	6	THR	HA	H	4.301	0.000
39	1	6	THR	HB	H	4.292	0.000
40	1	6	THR	HG21	H	1.210	0.000
41	1	6	THR	HG22	H	1.210	0.000
42	1	6	THR	HG23	H	1.210	0.000
43	1	6	THR	CA	C	61.989	0.000
44	1	6	THR	CB	C	69.706	0.000
45	1	6	THR	CG2	C	21.724	0.000
46	1	6	THR	N	N	112.710	0.000
47	1	7	THR	H	H	8.038	0.000
48	1	7	THR	HA	H	4.404	0.000
49	1	7	THR	HB	H	4.338	0.000
50	1	7	THR	HG21	H	1.248	0.000
51	1	7	THR	HG22	H	1.248	0.000
52	1	7	THR	HG23	H	1.248	0.000
53	1	7	THR	CA	C	61.997	0.000
54	1	7	THR	CB	C	70.028	0.000
55	1	7	THR	CG2	C	21.753	0.000
56	1	7	THR	N	N	114.686	0.000
57	1	8	LYS	H	H	8.296	0.000
58	1	8	LYS	HA	H	4.434	0.000
59	1	8	LYS	HB2	H	2.024	0.000
60	1	8	LYS	HB3	H	1.817	0.000
61	1	8	LYS	HG2	H	1.485	0.000
62	1	8	LYS	HG3	H	1.382	0.000
63	1	8	LYS	HD2	H	1.686	0.000
64	1	8	LYS	HD3	H	1.628	0.000
65	1	8	LYS	HE2	H	2.991	0.000
66	1	8	LYS	HE3	H	2.950	0.000
67	1	8	LYS	CA	C	56.953	0.000
68	1	8	LYS	CB	C	32.087	0.001
69	1	8	LYS	CG	C	25.435	0.002
70	1	8	LYS	CD	C	29.316	0.002
71	1	8	LYS	CE	C	42.239	0.014
72	1	8	LYS	N	N	120.055	0.000
73	1	9	ARG	H	H	7.980	0.000
74	1	9	ARG	HA	H	4.355	0.000
75	1	9	ARG	HB2	H	2.229	0.000
76	1	9	ARG	HB3	H	1.699	0.000
77	1	9	ARG	HG2	H	1.650	0.000
78	1	9	ARG	HG3	H	1.300	0.000
79	1	9	ARG	HD2	H	3.345	0.000
80	1	9	ARG	HD3	H	3.122	0.000
81	1	9	ARG	CA	C	56.252	0.000
82	1	9	ARG	CB	C	32.498	0.005
83	1	9	ARG	CG	C	27.559	0.012
84	1	9	ARG	CD	C	43.927	0.006
85	1	9	ARG	N	N	115.452	0.000
86	1	10	VAL	H	H	7.679	0.000
87	1	10	VAL	HA	H	4.404	0.000
88	1	10	VAL	HB	H	1.992	0.000
89	1	10	VAL	HG11	H	0.894	0.000
90	1	10	VAL	HG12	H	0.894	0.000
91	1	10	VAL	HG13	H	0.894	0.000
92	1	10	VAL	HG21	H	0.799	0.000
93	1	10	VAL	HG22	H	0.799	0.000
94	1	10	VAL	HG23	H	0.799	0.000
95	1	10	VAL	CA	C	62.007	0.000
96	1	10	VAL	CB	C	32.694	0.000
97	1	10	VAL	CG1	C	21.698	0.000
98	1	10	VAL	CG2	C	22.068	0.000
99	1	10	VAL	N	N	117.930	0.000
100	1	11	LEU	H	H	9.636	0.000
101	1	11	LEU	HA	H	4.942	0.000
102	1	11	LEU	HB2	H	1.638	0.000
103	1	11	LEU	HB3	H	1.255	0.000
104	1	11	LEU	HG	H	1.780	0.000
105	1	11	LEU	HD11	H	0.690	0.000
106	1	11	LEU	HD12	H	0.690	0.000
107	1	11	LEU	HD13	H	0.690	0.000
108	1	11	LEU	HD21	H	0.817	0.000
109	1	11	LEU	HD22	H	0.817	0.000
110	1	11	LEU	HD23	H	0.817	0.000
111	1	11	LEU	CA	C	53.516	0.000
112	1	11	LEU	CB	C	43.246	0.004
113	1	11	LEU	CG	C	27.006	0.000
114	1	11	LEU	CD1	C	25.039	0.000
115	1	11	LEU	CD2	C	26.557	0.000
116	1	11	LEU	N	N	127.508	0.000
117	1	12	TYR	H	H	9.161	0.000
118	1	12	TYR	HA	H	4.489	0.013
119	1	12	TYR	HB2	H	2.658	0.000
120	1	12	TYR	HB3	H	2.538	0.000
121	1	12	TYR	HD1	H	6.454	0.000
122	1	12	TYR	HD2	H	6.454	0.000
123	1	12	TYR	HE1	H	6.039	0.000
124	1	12	TYR	HE2	H	6.039	0.000
125	1	12	TYR	CA	C	56.336	0.000
126	1	12	TYR	CB	C	40.085	0.006
127	1	12	TYR	CD1	C	132.924	0.000
128	1	12	TYR	CE1	C	117.782	0.000
129	1	12	TYR	N	N	123.802	0.000
130	1	13	VAL	H	H	8.038	0.000
131	1	13	VAL	HA	H	4.674	0.000
132	1	13	VAL	HB	H	1.494	0.000
133	1	13	VAL	HG11	H	0.740	0.000
134	1	13	VAL	HG12	H	0.740	0.000
135	1	13	VAL	HG13	H	0.740	0.000
136	1	13	VAL	HG21	H	0.468	0.000
137	1	13	VAL	HG22	H	0.468	0.000
138	1	13	VAL	HG23	H	0.468	0.000
139	1	13	VAL	CA	C	60.201	0.000
140	1	13	VAL	CB	C	33.263	0.000
141	1	13	VAL	CG1	C	22.105	0.000
142	1	13	VAL	CG2	C	21.121	0.000
143	1	13	VAL	N	N	127.303	0.000
144	1	14	GLY	H	H	9.177	0.000
145	1	14	GLY	HA2	H	4.742	0.000
146	1	14	GLY	HA3	H	3.546	0.000
147	1	14	GLY	CA	C	43.197	0.001
148	1	14	GLY	N	N	112.296	0.000
149	1	15	GLY	H	H	8.081	0.000
150	1	15	GLY	HA2	H	4.366	0.000
151	1	15	GLY	HA3	H	3.736	0.000
152	1	15	GLY	CA	C	45.983	0.016
153	1	15	GLY	N	N	107.632	0.000
154	1	16	LEU	H	H	7.921	0.000
155	1	16	LEU	HA	H	4.038	0.000
156	1	16	LEU	HB2	H	1.120	0.000
157	1	16	LEU	HB3	H	0.851	0.000
158	1	16	LEU	HG	H	1.261	0.000
159	1	16	LEU	HD11	H	0.491	0.000
160	1	16	LEU	HD12	H	0.491	0.000
161	1	16	LEU	HD13	H	0.491	0.000
162	1	16	LEU	HD21	H	0.175	0.000
163	1	16	LEU	HD22	H	0.175	0.000
164	1	16	LEU	HD23	H	0.175	0.000
165	1	16	LEU	CA	C	53.998	0.000
166	1	16	LEU	CB	C	42.276	0.004
167	1	16	LEU	CG	C	26.307	0.000
168	1	16	LEU	CD1	C	22.565	0.000
169	1	16	LEU	CD2	C	25.572	0.000
170	1	16	LEU	N	N	116.405	0.000
171	1	17	ALA	H	H	8.516	0.000
172	1	17	ALA	HA	H	4.266	0.000
173	1	17	ALA	HB1	H	1.643	0.000
174	1	17	ALA	HB2	H	1.643	0.000
175	1	17	ALA	HB3	H	1.643	0.000
176	1	17	ALA	CA	C	51.503	0.000
177	1	17	ALA	CB	C	19.794	0.000
178	1	17	ALA	N	N	126.620	0.000
179	1	18	GLU	H	H	9.042	0.000
180	1	18	GLU	HA	H	3.590	0.000
181	1	18	GLU	HB2	H	1.953	0.000
182	1	18	GLU	HB3	H	1.851	0.000
183	1	18	GLU	HG2	H	2.201	0.000
184	1	18	GLU	HG3	H	2.201	0.000
185	1	18	GLU	CA	C	60.138	0.000
186	1	18	GLU	CB	C	29.646	0.011
187	1	18	GLU	CG	C	36.741	0.000
188	1	18	GLU	N	N	122.699	0.000
189	1	19	GLU	H	H	8.973	0.000
190	1	19	GLU	HA	H	3.969	0.000
191	1	19	GLU	HB2	H	1.765	0.000
192	1	19	GLU	HB3	H	1.509	0.000
193	1	19	GLU	HG2	H	2.234	0.000
194	1	19	GLU	HG3	H	2.096	0.000
195	1	19	GLU	CA	C	58.121	0.000
196	1	19	GLU	CB	C	29.127	0.003
197	1	19	GLU	CG	C	37.067	0.019
198	1	19	GLU	N	N	114.322	0.000
199	1	20	VAL	H	H	7.499	0.000
200	1	20	VAL	HA	H	3.097	0.000
201	1	20	VAL	HB	H	2.049	0.000
202	1	20	VAL	HG11	H	0.709	0.000
203	1	20	VAL	HG12	H	0.709	0.000
204	1	20	VAL	HG13	H	0.709	0.000
205	1	20	VAL	HG21	H	0.787	0.000
206	1	20	VAL	HG22	H	0.787	0.000
207	1	20	VAL	HG23	H	0.787	0.000
208	1	20	VAL	CA	C	65.318	0.000
209	1	20	VAL	CB	C	30.822	0.000
210	1	20	VAL	CG1	C	22.327	0.000
211	1	20	VAL	CG2	C	23.282	0.000
212	1	20	VAL	N	N	119.212	0.000
213	1	21	ASP	H	H	6.750	0.000
214	1	21	ASP	HA	H	4.660	0.000
215	1	21	ASP	HB2	H	3.163	0.000
216	1	21	ASP	HB3	H	2.727	0.000
217	1	21	ASP	CA	C	51.525	0.000
218	1	21	ASP	CB	C	42.822	0.005
219	1	21	ASP	N	N	125.176	0.000
220	1	22	ASP	H	H	8.774	0.000
221	1	22	ASP	HA	H	3.900	0.000
222	1	22	ASP	HB2	H	2.581	0.000
223	1	22	ASP	HB3	H	2.581	0.000
224	1	22	ASP	CA	C	57.587	0.000
225	1	22	ASP	CB	C	39.306	0.000
226	1	22	ASP	N	N	115.981	0.000
227	1	23	LYS	H	H	7.641	0.000
228	1	23	LYS	HA	H	4.064	0.000
229	1	23	LYS	HB2	H	2.100	0.000
230	1	23	LYS	HB3	H	1.872	0.000
231	1	23	LYS	HG2	H	1.512	0.000
232	1	23	LYS	HG3	H	1.417	0.000
233	1	23	LYS	HD2	H	1.660	0.000
234	1	23	LYS	HD3	H	1.660	0.000
235	1	23	LYS	HE2	H	2.993	0.000
236	1	23	LYS	HE3	H	2.993	0.000
237	1	23	LYS	CA	C	59.440	0.000
238	1	23	LYS	CB	C	31.611	0.000
239	1	23	LYS	CG	C	25.190	0.006
240	1	23	LYS	CD	C	28.809	0.000
241	1	23	LYS	CE	C	42.079	0.000
242	1	23	LYS	N	N	121.382	0.000
243	1	24	VAL	H	H	8.284	0.000
244	1	24	VAL	HA	H	3.782	0.000
245	1	24	VAL	HB	H	2.160	0.000
246	1	24	VAL	HG11	H	0.941	0.000
247	1	24	VAL	HG12	H	0.941	0.000
248	1	24	VAL	HG13	H	0.941	0.000
249	1	24	VAL	HG21	H	1.239	0.000
250	1	24	VAL	HG22	H	1.239	0.000
251	1	24	VAL	HG23	H	1.239	0.000
252	1	24	VAL	CA	C	66.001	0.000
253	1	24	VAL	CB	C	32.423	0.000
254	1	24	VAL	CG1	C	22.476	0.000
255	1	24	VAL	CG2	C	22.508	0.000
256	1	24	VAL	N	N	122.261	0.000
257	1	25	LEU	H	H	8.031	0.000
258	1	25	LEU	HA	H	4.052	0.000
259	1	25	LEU	HB2	H	1.709	0.000
260	1	25	LEU	HB3	H	1.229	0.000
261	1	25	LEU	HG	H	1.497	0.000
262	1	25	LEU	HD11	H	0.568	0.000
263	1	25	LEU	HD12	H	0.568	0.000
264	1	25	LEU	HD13	H	0.568	0.000
265	1	25	LEU	HD21	H	0.417	0.000
266	1	25	LEU	HD22	H	0.417	0.000
267	1	25	LEU	HD23	H	0.417	0.000
268	1	25	LEU	CA	C	58.088	0.000
269	1	25	LEU	CB	C	42.619	0.000
270	1	25	LEU	CG	C	26.344	0.000
271	1	25	LEU	CD1	C	23.828	0.000
272	1	25	LEU	CD2	C	26.059	0.000
273	1	25	LEU	N	N	118.592	0.000
274	1	26	HIS	H	H	8.602	0.000
275	1	26	HIS	HA	H	3.795	0.000
276	1	26	HIS	HB2	H	3.181	0.000
277	1	26	HIS	HB3	H	3.129	0.000
278	1	26	HIS	HD2	H	6.831	0.000
279	1	26	HIS	HE1	H	7.861	0.000
280	1	26	HIS	CA	C	61.929	0.000
281	1	26	HIS	CB	C	30.547	0.003
282	1	26	HIS	CD2	C	118.681	0.000
283	1	26	HIS	CE1	C	138.011	0.000
284	1	26	HIS	N	N	119.088	0.000
285	1	27	ALA	H	H	7.824	0.000
286	1	27	ALA	HA	H	4.109	0.000
287	1	27	ALA	HB1	H	1.551	0.000
288	1	27	ALA	HB2	H	1.551	0.000
289	1	27	ALA	HB3	H	1.551	0.000
290	1	27	ALA	CA	C	54.870	0.000
291	1	27	ALA	CB	C	18.244	0.000
292	1	27	ALA	N	N	117.935	0.000
293	1	28	ALA	H	H	7.887	0.000
294	1	28	ALA	HA	H	4.134	0.000
295	1	28	ALA	HB1	H	1.324	0.000
296	1	28	ALA	HB2	H	1.324	0.000
297	1	28	ALA	HB3	H	1.324	0.000
298	1	28	ALA	CA	C	53.654	0.000
299	1	28	ALA	CB	C	18.735	0.000
300	1	28	ALA	N	N	117.305	0.000
301	1	29	PHE	H	H	7.827	0.000
302	1	29	PHE	HA	H	4.961	0.000
303	1	29	PHE	HB2	H	3.397	0.000
304	1	29	PHE	HB3	H	2.838	0.000
305	1	29	PHE	HD1	H	7.696	0.000
306	1	29	PHE	HD2	H	7.696	0.000
307	1	29	PHE	HE1	H	6.908	0.000
308	1	29	PHE	HE2	H	6.908	0.000
309	1	29	PHE	HZ	H	6.913	0.000
310	1	29	PHE	CA	C	60.383	0.000
311	1	29	PHE	CB	C	40.718	0.008
312	1	29	PHE	CD1	C	131.739	0.000
313	1	29	PHE	CE1	C	130.243	0.000
314	1	29	PHE	CZ	C	128.748	0.000
315	1	29	PHE	N	N	112.220	0.000
316	1	30	ILE	H	H	8.616	0.000
317	1	30	ILE	HA	H	3.777	0.000
318	1	30	ILE	HB	H	1.555	0.000
319	1	30	ILE	HG12	H	1.403	0.000
320	1	30	ILE	HG13	H	1.306	0.000
321	1	30	ILE	HG21	H	0.918	0.000
322	1	30	ILE	HG22	H	0.918	0.000
323	1	30	ILE	HG23	H	0.918	0.000
324	1	30	ILE	HD11	H	1.065	0.000
325	1	30	ILE	HD12	H	1.065	0.000
326	1	30	ILE	HD13	H	1.065	0.000
327	1	30	ILE	CA	C	61.931	0.000
328	1	30	ILE	CB	C	38.464	0.000
329	1	30	ILE	CG1	C	29.703	0.012
330	1	30	ILE	CG2	C	19.511	0.000
331	1	30	ILE	CD1	C	14.600	0.000
332	1	30	ILE	N	N	123.376	0.000
333	1	31	PRO	HA	H	4.100	0.000
334	1	31	PRO	HB2	H	1.920	0.000
335	1	31	PRO	HB3	H	0.391	0.000
336	1	31	PRO	HG2	H	1.611	0.000
337	1	31	PRO	HG3	H	1.611	0.000
338	1	31	PRO	HD2	H	3.759	0.000
339	1	31	PRO	HD3	H	2.904	0.000
340	1	31	PRO	CA	C	65.420	0.000
341	1	31	PRO	CB	C	30.817	0.016
342	1	31	PRO	CG	C	28.394	0.000
343	1	31	PRO	CD	C	52.204	0.002
344	1	32	PHE	H	H	7.564	0.000
345	1	32	PHE	HA	H	4.163	0.000
346	1	32	PHE	HB2	H	3.290	0.000
347	1	32	PHE	HB3	H	2.986	0.000
348	1	32	PHE	HD1	H	7.196	0.000
349	1	32	PHE	HD2	H	7.196	0.000
350	1	32	PHE	HE1	H	7.565	0.000
351	1	32	PHE	HE2	H	7.565	0.000
352	1	32	PHE	HZ	H	7.351	0.000
353	1	32	PHE	CA	C	59.660	0.000
354	1	32	PHE	CB	C	38.855	0.007
355	1	32	PHE	CD1	C	131.930	0.000
356	1	32	PHE	CE1	C	131.584	0.000
357	1	32	PHE	CZ	C	131.651	0.000
358	1	32	PHE	N	N	112.134	0.000
359	1	33	GLY	H	H	7.593	0.000
360	1	33	GLY	HA2	H	4.968	0.000
361	1	33	GLY	HA3	H	3.744	0.000
362	1	33	GLY	CA	C	44.460	0.002
363	1	33	GLY	N	N	106.037	0.000
364	1	34	ASP	H	H	7.994	0.000
365	1	34	ASP	HA	H	4.461	0.000
366	1	34	ASP	HB2	H	2.592	0.000
367	1	34	ASP	HB3	H	2.592	0.000
368	1	34	ASP	CA	C	56.592	0.000
369	1	34	ASP	CB	C	41.131	0.000
370	1	34	ASP	N	N	114.401	0.000
371	1	35	ILE	H	H	7.478	0.000
372	1	35	ILE	HA	H	4.835	0.000
373	1	35	ILE	HB	H	1.358	0.000
374	1	35	ILE	HG12	H	1.640	0.000
375	1	35	ILE	HG13	H	-0.246	0.000
376	1	35	ILE	HG21	H	0.607	0.000
377	1	35	ILE	HG22	H	0.607	0.000
378	1	35	ILE	HG23	H	0.607	0.000
379	1	35	ILE	HD11	H	0.344	0.000
380	1	35	ILE	HD12	H	0.344	0.000
381	1	35	ILE	HD13	H	0.344	0.000
382	1	35	ILE	CA	C	58.167	0.000
383	1	35	ILE	CB	C	41.700	0.000
384	1	35	ILE	CG1	C	27.614	0.013
385	1	35	ILE	CG2	C	17.256	0.000
386	1	35	ILE	CD1	C	14.504	0.000
387	1	35	ILE	N	N	124.534	0.000
388	1	36	THR	H	H	9.014	0.000
389	1	36	THR	HA	H	4.220	0.000
390	1	36	THR	HB	H	3.957	0.000
391	1	36	THR	HG21	H	1.031	0.000
392	1	36	THR	HG22	H	1.031	0.000
393	1	36	THR	HG23	H	1.031	0.000
394	1	36	THR	CA	C	63.209	0.000
395	1	36	THR	CB	C	68.721	0.000
396	1	36	THR	CG2	C	22.743	0.000
397	1	36	THR	N	N	121.563	0.000
398	1	37	ASP	H	H	7.565	0.000
399	1	37	ASP	HA	H	4.743	0.000
400	1	37	ASP	HB2	H	2.704	0.000
401	1	37	ASP	HB3	H	2.357	0.000
402	1	37	ASP	CA	C	55.062	0.000
403	1	37	ASP	CB	C	44.238	0.002
404	1	37	ASP	N	N	119.800	0.000
405	1	38	ILE	H	H	7.938	0.000
406	1	38	ILE	HA	H	4.243	0.000
407	1	38	ILE	HB	H	1.634	0.000
408	1	38	ILE	HG12	H	1.618	0.000
409	1	38	ILE	HG13	H	0.856	0.000
410	1	38	ILE	HG21	H	0.653	0.000
411	1	38	ILE	HG22	H	0.653	0.000
412	1	38	ILE	HG23	H	0.653	0.000
413	1	38	ILE	HD11	H	0.857	0.000
414	1	38	ILE	HD12	H	0.857	0.000
415	1	38	ILE	HD13	H	0.857	0.000
416	1	38	ILE	CA	C	61.260	0.000
417	1	38	ILE	CB	C	41.697	0.000
418	1	38	ILE	CG1	C	28.680	0.001
419	1	38	ILE	CG2	C	17.058	0.000
420	1	38	ILE	CD1	C	13.703	0.000
421	1	38	ILE	N	N	122.760	0.000
422	1	39	GLN	H	H	8.966	0.000
423	1	39	GLN	HA	H	4.661	0.000
424	1	39	GLN	HB2	H	2.120	0.000
425	1	39	GLN	HB3	H	1.887	0.000
426	1	39	GLN	HG2	H	2.227	0.000
427	1	39	GLN	HG3	H	2.227	0.000
428	1	39	GLN	HE21	H	8.062	0.000
429	1	39	GLN	HE22	H	6.635	0.000
430	1	39	GLN	CA	C	54.310	0.000
431	1	39	GLN	CB	C	32.091	0.004
432	1	39	GLN	CG	C	33.225	0.000
433	1	39	GLN	N	N	125.816	0.000
434	1	39	GLN	NE2	N	112.874	0.001
435	1	40	ILE	H	H	8.739	0.000
436	1	40	ILE	HB	H	1.718	0.000
437	1	40	ILE	HG12	H	1.269	0.000
438	1	40	ILE	HG13	H	0.491	0.000
439	1	40	ILE	HG21	H	0.574	0.000
440	1	40	ILE	HG22	H	0.574	0.000
441	1	40	ILE	HG23	H	0.574	0.000
442	1	40	ILE	HD11	H	0.488	0.000
443	1	40	ILE	HD12	H	0.488	0.000
444	1	40	ILE	HD13	H	0.488	0.000
445	1	40	ILE	CB	C	38.772	0.000
446	1	40	ILE	CG1	C	26.660	0.005
447	1	40	ILE	CG2	C	17.538	0.000
448	1	40	ILE	CD1	C	13.243	0.000
449	1	40	ILE	N	N	124.065	0.000
450	1	41	PRO	HA	H	4.359	0.000
451	1	41	PRO	HB2	H	2.356	0.000
452	1	41	PRO	HB3	H	1.532	0.000
453	1	41	PRO	HG2	H	1.876	0.000
454	1	41	PRO	HG3	H	1.876	0.000
455	1	41	PRO	HD2	H	3.564	0.000
456	1	41	PRO	HD3	H	3.176	0.000
457	1	41	PRO	CA	C	58.376	0.000
458	1	41	PRO	CB	C	32.377	0.010
459	1	41	PRO	CG	C	27.909	0.000
460	1	41	PRO	CD	C	50.397	0.007
461	1	42	LEU	H	H	8.284	0.000
462	1	42	LEU	HA	H	4.468	0.000
463	1	42	LEU	HB2	H	1.439	0.000
464	1	42	LEU	HB3	H	0.941	0.000
465	1	42	LEU	HG	H	1.627	0.000
466	1	42	LEU	HD11	H	0.582	0.000
467	1	42	LEU	HD12	H	0.582	0.000
468	1	42	LEU	HD13	H	0.582	0.000
469	1	42	LEU	HD21	H	0.751	0.000
470	1	42	LEU	HD22	H	0.751	0.000
471	1	42	LEU	HD23	H	0.751	0.000
472	1	42	LEU	CA	C	53.397	0.000
473	1	42	LEU	CB	C	44.395	0.003
474	1	42	LEU	CG	C	26.528	0.000
475	1	42	LEU	CD1	C	22.839	0.000
476	1	42	LEU	CD2	C	25.152	0.000
477	1	42	LEU	N	N	121.509	0.000
478	1	43	ASP	H	H	8.543	0.000
479	1	43	ASP	HA	H	4.670	0.000
480	1	43	ASP	HB2	H	3.153	0.000
481	1	43	ASP	HB3	H	2.372	0.000
482	1	43	ASP	CA	C	53.884	0.000
483	1	43	ASP	CB	C	42.578	0.006
484	1	43	ASP	N	N	122.366	0.000
485	1	44	TYR	HA	H	4.118	0.000
486	1	44	TYR	HB2	H	2.986	0.000
487	1	44	TYR	HB3	H	2.986	0.000
488	1	44	TYR	HD1	H	7.035	0.000
489	1	44	TYR	HD2	H	7.035	0.000
490	1	44	TYR	HE1	H	6.745	0.000
491	1	44	TYR	HE2	H	6.745	0.000
492	1	44	TYR	CA	C	60.777	0.000
493	1	44	TYR	CB	C	38.365	0.000
494	1	44	TYR	CD1	C	133.042	0.000
495	1	44	TYR	CE1	C	118.409	0.000
496	1	45	GLU	H	H	8.507	0.000
497	1	45	GLU	HA	H	4.090	0.000
498	1	45	GLU	HB2	H	2.123	0.000
499	1	45	GLU	HB3	H	2.072	0.000
500	1	45	GLU	HG2	H	2.237	0.000
501	1	45	GLU	HG3	H	2.133	0.000
502	1	45	GLU	CA	C	58.708	0.000
503	1	45	GLU	CB	C	30.331	0.006
504	1	45	GLU	CG	C	36.831	0.010
505	1	45	GLU	N	N	117.238	0.000
506	1	46	THR	H	H	7.864	0.000
507	1	46	THR	HA	H	4.235	0.000
508	1	46	THR	HB	H	4.226	0.000
509	1	46	THR	HG21	H	1.163	0.000
510	1	46	THR	HG22	H	1.163	0.000
511	1	46	THR	HG23	H	1.163	0.000
512	1	46	THR	CA	C	61.983	0.000
513	1	46	THR	CB	C	70.619	0.000
514	1	46	THR	CG2	C	21.673	0.000
515	1	46	THR	N	N	107.385	0.000
516	1	47	GLU	H	H	8.298	0.000
517	1	47	GLU	HA	H	3.730	0.000
518	1	47	GLU	HB2	H	2.214	0.000
519	1	47	GLU	HB3	H	2.190	0.000
520	1	47	GLU	HG2	H	2.074	0.000
521	1	47	GLU	HG3	H	2.074	0.000
522	1	47	GLU	CA	C	58.223	0.000
523	1	47	GLU	CB	C	27.310	0.006
524	1	47	GLU	CG	C	37.344	0.000
525	1	47	GLU	N	N	116.137	0.000
526	1	48	LYS	H	H	7.655	0.000
527	1	48	LYS	HA	H	4.598	0.000
528	1	48	LYS	HB2	H	1.792	0.000
529	1	48	LYS	HB3	H	1.541	0.000
530	1	48	LYS	HG2	H	1.371	0.000
531	1	48	LYS	HG3	H	1.329	0.000
532	1	48	LYS	HD2	H	1.586	0.000
533	1	48	LYS	HD3	H	1.533	0.000
534	1	48	LYS	HE2	H	2.933	0.000
535	1	48	LYS	HE3	H	2.933	0.000
536	1	48	LYS	CA	C	54.551	0.000
537	1	48	LYS	CB	C	35.436	0.011
538	1	48	LYS	CG	C	24.809	0.003
539	1	48	LYS	CD	C	29.114	0.010
540	1	48	LYS	CE	C	42.335	0.000
541	1	48	LYS	N	N	117.598	0.000
542	1	49	HIS	H	H	8.135	0.000
543	1	49	HIS	HA	H	4.899	0.000
544	1	49	HIS	HB2	H	3.438	0.000
545	1	49	HIS	HB3	H	2.756	0.000
546	1	49	HIS	HD2	H	7.106	0.000
547	1	49	HIS	HE1	H	7.337	0.000
548	1	49	HIS	CA	C	55.776	0.000
549	1	49	HIS	CB	C	31.052	0.019
550	1	49	HIS	CD2	C	118.988	0.000
551	1	49	HIS	CE1	C	139.039	0.000
552	1	49	HIS	N	N	117.992	0.000
553	1	50	ARG	H	H	8.823	0.000
554	1	50	ARG	HA	H	4.467	0.000
555	1	50	ARG	HB2	H	2.383	0.000
556	1	50	ARG	HB3	H	1.516	0.000
557	1	50	ARG	HG2	H	1.621	0.000
558	1	50	ARG	HG3	H	1.500	0.000
559	1	50	ARG	HD2	H	3.123	0.000
560	1	50	ARG	HD3	H	3.023	0.000
561	1	50	ARG	CA	C	53.295	0.000
562	1	50	ARG	CB	C	31.438	0.015
563	1	50	ARG	CG	C	27.604	0.006
564	1	50	ARG	CD	C	44.256	0.000
565	1	50	ARG	N	N	119.143	0.000
566	1	51	GLY	H	H	10.777	0.000
567	1	51	GLY	HA2	H	4.466	0.000
568	1	51	GLY	HA3	H	3.876	0.000
569	1	51	GLY	CA	C	45.645	0.001
570	1	51	GLY	N	N	112.706	0.000
571	1	52	PHE	H	H	6.957	0.000
572	1	52	PHE	HA	H	5.508	0.000
573	1	52	PHE	HB2	H	2.870	0.000
574	1	52	PHE	HB3	H	2.474	0.000
575	1	52	PHE	HD1	H	6.635	0.000
576	1	52	PHE	HD2	H	6.635	0.000
577	1	52	PHE	HE1	H	7.233	0.000
578	1	52	PHE	HE2	H	7.233	0.000
579	1	52	PHE	HZ	H	7.280	0.000
580	1	52	PHE	CA	C	54.740	0.000
581	1	52	PHE	CB	C	42.087	0.019
582	1	52	PHE	CD1	C	132.694	0.000
583	1	52	PHE	CE1	C	131.129	0.000
584	1	52	PHE	CZ	C	128.958	0.000
585	1	52	PHE	N	N	114.694	0.000
586	1	53	ALA	H	H	8.606	0.000
587	1	53	ALA	HA	H	4.363	0.000
588	1	53	ALA	HB1	H	0.799	0.000
589	1	53	ALA	HB2	H	0.799	0.000
590	1	53	ALA	HB3	H	0.799	0.000
591	1	53	ALA	CA	C	49.946	0.000
592	1	53	ALA	CB	C	25.940	0.000
593	1	53	ALA	N	N	119.677	0.000
594	1	54	PHE	H	H	8.615	0.000
595	1	54	PHE	HA	H	5.738	0.000
596	1	54	PHE	HB2	H	2.698	0.000
597	1	54	PHE	HB3	H	2.533	0.000
598	1	54	PHE	HD1	H	6.960	0.000
599	1	54	PHE	HD2	H	6.960	0.000
600	1	54	PHE	HE1	H	7.164	0.000
601	1	54	PHE	HE2	H	7.164	0.000
602	1	54	PHE	CA	C	55.820	0.000
603	1	54	PHE	CB	C	41.925	0.006
604	1	54	PHE	CD1	C	131.757	0.000
605	1	54	PHE	CE1	C	130.357	0.000
606	1	54	PHE	N	N	114.371	0.000
607	1	55	VAL	H	H	8.657	0.000
608	1	55	VAL	HA	H	4.242	0.000
609	1	55	VAL	HB	H	1.354	0.000
610	1	55	VAL	HG11	H	0.218	0.000
611	1	55	VAL	HG12	H	0.218	0.000
612	1	55	VAL	HG13	H	0.218	0.000
613	1	55	VAL	HG21	H	0.206	0.000
614	1	55	VAL	HG22	H	0.206	0.000
615	1	55	VAL	HG23	H	0.206	0.000
616	1	55	VAL	CA	C	61.230	0.000
617	1	55	VAL	CB	C	34.934	0.000
618	1	55	VAL	CG1	C	20.291	0.000
619	1	55	VAL	CG2	C	21.197	0.000
620	1	55	VAL	N	N	122.657	0.000
621	1	56	GLU	H	H	8.992	0.000
622	1	56	GLU	HA	H	5.111	0.000
623	1	56	GLU	HB2	H	2.060	0.000
624	1	56	GLU	HB3	H	1.709	0.000
625	1	56	GLU	HG2	H	2.025	0.000
626	1	56	GLU	HG3	H	1.904	0.000
627	1	56	GLU	CA	C	54.421	0.000
628	1	56	GLU	CB	C	33.169	0.002
629	1	56	GLU	CG	C	36.745	0.008
630	1	56	GLU	N	N	129.337	0.000
631	1	57	PHE	H	H	8.692	0.000
632	1	57	PHE	HA	H	4.832	0.000
633	1	57	PHE	HB2	H	3.704	0.000
634	1	57	PHE	HB3	H	2.651	0.000
635	1	57	PHE	HD1	H	7.192	0.000
636	1	57	PHE	HD2	H	7.192	0.000
637	1	57	PHE	HE1	H	7.560	0.000
638	1	57	PHE	HE2	H	7.560	0.000
639	1	57	PHE	HZ	H	7.171	0.000
640	1	57	PHE	CA	C	58.215	0.000
641	1	57	PHE	CB	C	41.477	0.002
642	1	57	PHE	CD1	C	131.354	0.000
643	1	57	PHE	CE1	C	129.073	0.000
644	1	57	PHE	CZ	C	129.598	0.000
645	1	57	PHE	N	N	126.482	0.000
646	1	58	GLU	H	H	8.133	0.000
647	1	58	GLU	HA	H	3.943	0.000
648	1	58	GLU	HB2	H	2.266	0.000
649	1	58	GLU	HB3	H	2.018	0.000
650	1	58	GLU	HG2	H	2.199	0.000
651	1	58	GLU	HG3	H	2.199	0.000
652	1	58	GLU	CA	C	59.881	0.000
653	1	58	GLU	CB	C	30.111	0.061
654	1	58	GLU	CG	C	36.242	0.000
655	1	58	GLU	N	N	121.298	0.000
656	1	59	LEU	H	H	9.324	0.000
657	1	59	LEU	HA	H	4.843	0.000
658	1	59	LEU	HB2	H	1.838	0.000
659	1	59	LEU	HB3	H	1.611	0.000
660	1	59	LEU	HG	H	1.701	0.000
661	1	59	LEU	HD11	H	0.957	0.000
662	1	59	LEU	HD12	H	0.957	0.000
663	1	59	LEU	HD13	H	0.957	0.000
664	1	59	LEU	HD21	H	1.033	0.000
665	1	59	LEU	HD22	H	1.033	0.000
666	1	59	LEU	HD23	H	1.033	0.000
667	1	59	LEU	CA	C	53.039	0.000
668	1	59	LEU	CB	C	43.265	0.004
669	1	59	LEU	CG	C	26.899	0.000
670	1	59	LEU	CD1	C	23.251	0.000
671	1	59	LEU	CD2	C	25.315	0.000
672	1	59	LEU	N	N	116.304	0.000
673	1	60	ALA	H	H	9.023	0.000
674	1	60	ALA	HA	H	3.921	0.000
675	1	60	ALA	HB1	H	1.388	0.000
676	1	60	ALA	HB2	H	1.388	0.000
677	1	60	ALA	HB3	H	1.388	0.000
678	1	60	ALA	CA	C	55.254	0.000
679	1	60	ALA	CB	C	18.646	0.000
680	1	60	ALA	N	N	127.174	0.000
681	1	61	GLU	H	H	9.968	0.000
682	1	61	GLU	HA	H	4.054	0.000
683	1	61	GLU	HB2	H	2.015	0.000
684	1	61	GLU	HB3	H	2.015	0.000
685	1	61	GLU	HG2	H	2.432	0.000
686	1	61	GLU	HG3	H	2.323	0.000
687	1	61	GLU	CA	C	59.837	0.000
688	1	61	GLU	CB	C	28.646	0.000
689	1	61	GLU	CG	C	36.763	0.009
690	1	61	GLU	N	N	118.598	0.000
691	1	62	ASP	H	H	6.817	0.000
692	1	62	ASP	HA	H	4.425	0.000
693	1	62	ASP	HB2	H	2.908	0.000
694	1	62	ASP	HB3	H	2.585	0.000
695	1	62	ASP	CA	C	56.608	0.000
696	1	62	ASP	CB	C	40.014	0.006
697	1	62	ASP	N	N	124.017	0.000
698	1	63	ALA	H	H	6.981	0.000
699	1	63	ALA	HA	H	3.107	0.000
700	1	63	ALA	HB1	H	1.352	0.000
701	1	63	ALA	HB2	H	1.352	0.000
702	1	63	ALA	HB3	H	1.352	0.000
703	1	63	ALA	CA	C	54.560	0.000
704	1	63	ALA	CB	C	17.434	0.000
705	1	63	ALA	N	N	121.739	0.000
706	1	64	ALA	H	H	7.789	0.000
707	1	64	ALA	HA	H	3.865	0.000
708	1	64	ALA	HB1	H	1.418	0.000
709	1	64	ALA	HB2	H	1.418	0.000
710	1	64	ALA	HB3	H	1.418	0.000
711	1	64	ALA	CA	C	55.043	0.000
712	1	64	ALA	CB	C	17.882	0.000
713	1	64	ALA	N	N	117.698	0.000
714	1	65	ALA	H	H	7.327	0.000
715	1	65	ALA	HA	H	4.100	0.000
716	1	65	ALA	HB1	H	1.630	0.000
717	1	65	ALA	HB2	H	1.630	0.000
718	1	65	ALA	HB3	H	1.630	0.000
719	1	65	ALA	CA	C	54.848	0.000
720	1	65	ALA	CB	C	18.204	0.000
721	1	65	ALA	N	N	121.300	0.000
722	1	66	ALA	H	H	7.850	0.000
723	1	66	ALA	HA	H	2.402	0.000
724	1	66	ALA	HB1	H	1.154	0.000
725	1	66	ALA	HB2	H	1.154	0.000
726	1	66	ALA	HB3	H	1.154	0.000
727	1	66	ALA	CA	C	54.726	0.000
728	1	66	ALA	CB	C	19.051	0.000
729	1	66	ALA	N	N	122.124	0.000
730	1	67	ILE	H	H	7.852	0.000
731	1	67	ILE	HA	H	3.217	0.000
732	1	67	ILE	HB	H	1.831	0.000
733	1	67	ILE	HG12	H	1.844	0.000
734	1	67	ILE	HG13	H	0.524	0.000
735	1	67	ILE	HG21	H	0.926	0.000
736	1	67	ILE	HG22	H	0.926	0.000
737	1	67	ILE	HG23	H	0.926	0.000
738	1	67	ILE	HD11	H	0.789	0.000
739	1	67	ILE	HD12	H	0.789	0.000
740	1	67	ILE	HD13	H	0.789	0.000
741	1	67	ILE	CA	C	66.689	0.000
742	1	67	ILE	CB	C	38.517	0.000
743	1	67	ILE	CG1	C	30.316	0.008
744	1	67	ILE	CG2	C	17.377	0.000
745	1	67	ILE	CD1	C	14.076	0.000
746	1	67	ILE	N	N	118.724	0.000
747	1	68	ASP	H	H	7.439	0.000
748	1	68	ASP	HA	H	4.281	0.000
749	1	68	ASP	HB2	H	2.649	0.000
750	1	68	ASP	HB3	H	2.603	0.000
751	1	68	ASP	CA	C	57.182	0.000
752	1	68	ASP	CB	C	40.992	0.001
753	1	68	ASP	N	N	116.652	0.000
754	1	69	ASN	H	H	7.433	0.000
755	1	69	ASN	HA	H	4.611	0.000
756	1	69	ASN	HB2	H	2.552	0.000
757	1	69	ASN	HB3	H	2.348	0.000
758	1	69	ASN	HD21	H	7.708	0.000
759	1	69	ASN	HD22	H	7.279	0.000
760	1	69	ASN	CA	C	55.401	0.000
761	1	69	ASN	CB	C	42.409	0.008
762	1	69	ASN	N	N	112.748	0.000
763	1	69	ASN	ND2	N	115.401	0.000
764	1	70	MET	H	H	8.259	0.003
765	1	70	MET	HA	H	4.844	0.000
766	1	70	MET	HB2	H	2.081	0.000
767	1	70	MET	HB3	H	1.677	0.000
768	1	70	MET	HG2	H	1.998	0.000
769	1	70	MET	HG3	H	1.810	0.000
770	1	70	MET	HE1	H	1.372	0.000
771	1	70	MET	HE2	H	1.372	0.000
772	1	70	MET	HE3	H	1.372	0.000
773	1	70	MET	CA	C	53.834	0.000
774	1	70	MET	CB	C	32.957	0.000
775	1	70	MET	CG	C	33.550	0.018
776	1	70	MET	CE	C	16.720	0.000
777	1	70	MET	N	N	113.662	0.000
778	1	71	ASN	H	H	8.179	0.000
779	1	71	ASN	HA	H	4.371	0.000
780	1	71	ASN	HB2	H	3.265	0.000
781	1	71	ASN	HB3	H	2.965	0.000
782	1	71	ASN	HD21	H	7.964	0.000
783	1	71	ASN	HD22	H	7.132	0.000
784	1	71	ASN	CA	C	56.395	0.000
785	1	71	ASN	CB	C	38.841	0.001
786	1	71	ASN	N	N	119.542	0.000
787	1	71	ASN	ND2	N	116.174	0.001
788	1	72	GLU	H	H	8.637	0.005
789	1	72	GLU	HA	H	3.966	0.012
790	1	72	GLU	HB2	H	2.307	0.000
791	1	72	GLU	HB3	H	2.195	0.000
792	1	72	GLU	HG2	H	2.276	0.010
793	1	72	GLU	HG3	H	2.139	0.000
794	1	72	GLU	CA	C	58.909	0.000
795	1	72	GLU	CB	C	26.727	0.003
796	1	72	GLU	CG	C	37.204	0.001
797	1	72	GLU	N	N	121.521	0.000
798	1	73	SER	H	H	7.674	0.000
799	1	73	SER	HA	H	4.598	0.000
800	1	73	SER	HB2	H	4.053	0.000
801	1	73	SER	HB3	H	3.816	0.000
802	1	73	SER	CA	C	58.118	0.000
803	1	73	SER	CB	C	65.097	0.003
804	1	73	SER	N	N	115.034	0.000
805	1	74	GLU	H	H	8.288	0.000
806	1	74	GLU	HA	H	4.954	0.000
807	1	74	GLU	HB2	H	1.832	0.000
808	1	74	GLU	HB3	H	1.780	0.000
809	1	74	GLU	HG2	H	2.068	0.000
810	1	74	GLU	HG3	H	1.889	0.000
811	1	74	GLU	CA	C	55.368	0.000
812	1	74	GLU	CB	C	32.082	0.010
813	1	74	GLU	CG	C	36.728	0.002
814	1	74	GLU	N	N	117.930	0.000
815	1	75	LEU	H	H	9.027	0.000
816	1	75	LEU	HA	H	4.569	0.000
817	1	75	LEU	HB2	H	1.725	0.000
818	1	75	LEU	HB3	H	1.342	0.000
819	1	75	LEU	HG	H	1.701	0.000
820	1	75	LEU	HD11	H	0.808	0.000
821	1	75	LEU	HD12	H	0.808	0.000
822	1	75	LEU	HD13	H	0.808	0.000
823	1	75	LEU	HD21	H	0.695	0.000
824	1	75	LEU	HD22	H	0.695	0.000
825	1	75	LEU	HD23	H	0.695	0.000
826	1	75	LEU	CA	C	54.774	0.000
827	1	75	LEU	CB	C	44.996	0.001
828	1	75	LEU	CG	C	26.768	0.000
829	1	75	LEU	CD1	C	23.590	0.000
830	1	75	LEU	CD2	C	25.217	0.000
831	1	75	LEU	N	N	126.790	0.000
832	1	76	PHE	H	H	9.787	0.000
833	1	76	PHE	HA	H	3.929	0.000
834	1	76	PHE	HB2	H	3.478	0.000
835	1	76	PHE	HB3	H	2.715	0.000
836	1	76	PHE	HD1	H	7.127	0.005
837	1	76	PHE	HD2	H	7.127	0.005
838	1	76	PHE	HE1	H	7.297	0.000
839	1	76	PHE	HE2	H	7.297	0.000
840	1	76	PHE	CA	C	59.365	0.000
841	1	76	PHE	CB	C	37.162	0.002
842	1	76	PHE	CD1	C	131.020	0.000
843	1	76	PHE	CE1	C	131.601	0.000
844	1	76	PHE	N	N	128.734	0.000
845	1	77	GLY	H	H	8.684	0.000
846	1	77	GLY	HA2	H	4.053	0.000
847	1	77	GLY	HA3	H	3.642	0.000
848	1	77	GLY	CA	C	45.859	0.001
849	1	77	GLY	N	N	102.169	0.000
850	1	78	ARG	H	H	7.577	0.000
851	1	78	ARG	HA	H	4.784	0.000
852	1	78	ARG	HB2	H	2.057	0.000
853	1	78	ARG	HB3	H	1.810	0.000
854	1	78	ARG	HG2	H	1.701	0.000
855	1	78	ARG	HG3	H	1.701	0.000
856	1	78	ARG	HD2	H	3.163	0.000
857	1	78	ARG	HD3	H	3.163	0.000
858	1	78	ARG	CA	C	53.775	0.000
859	1	78	ARG	CB	C	33.220	0.057
860	1	78	ARG	CG	C	26.745	0.000
861	1	78	ARG	CD	C	43.114	0.000
862	1	78	ARG	N	N	119.176	0.000
863	1	79	THR	H	H	8.415	0.000
864	1	79	THR	HA	H	4.606	0.000
865	1	79	THR	HB	H	3.887	0.000
866	1	79	THR	HG21	H	1.097	0.000
867	1	79	THR	HG22	H	1.097	0.000
868	1	79	THR	HG23	H	1.097	0.000
869	1	79	THR	CA	C	63.049	0.000
870	1	79	THR	CB	C	69.442	0.000
871	1	79	THR	CG2	C	22.009	0.000
872	1	79	THR	N	N	119.102	0.000
873	1	80	ILE	H	H	8.794	0.000
874	1	80	ILE	HA	H	5.102	0.000
875	1	80	ILE	HB	H	1.898	0.000
876	1	80	ILE	HG21	H	0.812	0.000
877	1	80	ILE	HG22	H	0.812	0.000
878	1	80	ILE	HG23	H	0.812	0.000
879	1	80	ILE	HD11	H	0.625	0.000
880	1	80	ILE	HD12	H	0.625	0.000
881	1	80	ILE	HD13	H	0.625	0.000
882	1	80	ILE	CA	C	60.024	0.000
883	1	80	ILE	CB	C	40.646	0.000
884	1	80	ILE	CG2	C	19.071	0.000
885	1	80	ILE	CD1	C	14.290	0.000
886	1	80	ILE	N	N	121.650	0.000
887	1	81	ARG	H	H	8.217	0.000
888	1	81	ARG	HA	H	4.973	0.000
889	1	81	ARG	HB2	H	1.801	0.000
890	1	81	ARG	HB3	H	1.672	0.000
891	1	81	ARG	HG2	H	1.669	0.000
892	1	81	ARG	HG3	H	1.637	0.000
893	1	81	ARG	HD2	H	3.254	0.000
894	1	81	ARG	HD3	H	3.254	0.000
895	1	81	ARG	CA	C	53.760	0.000
896	1	81	ARG	CB	C	32.507	0.000
897	1	81	ARG	CG	C	27.265	0.000
898	1	81	ARG	CD	C	43.166	0.000
899	1	81	ARG	N	N	121.960	0.000
900	1	82	VAL	H	H	8.955	0.000
901	1	82	VAL	HA	H	5.350	0.000
902	1	82	VAL	HB	H	1.794	0.000
903	1	82	VAL	HG11	H	0.997	0.000
904	1	82	VAL	HG12	H	0.997	0.000
905	1	82	VAL	HG13	H	0.997	0.000
906	1	82	VAL	HG21	H	0.974	0.000
907	1	82	VAL	HG22	H	0.974	0.000
908	1	82	VAL	HG23	H	0.974	0.000
909	1	82	VAL	CA	C	60.439	0.000
910	1	82	VAL	CB	C	35.170	0.000
911	1	82	VAL	CG1	C	22.484	0.000
912	1	82	VAL	CG2	C	24.476	0.000
913	1	82	VAL	N	N	123.042	0.000
914	1	83	ASN	H	H	9.006	0.000
915	1	83	ASN	HA	H	4.818	0.000
916	1	83	ASN	HB2	H	2.988	0.000
917	1	83	ASN	HB3	H	2.790	0.000
918	1	83	ASN	HD21	H	7.323	0.000
919	1	83	ASN	HD22	H	6.796	0.000
920	1	83	ASN	CA	C	51.847	0.000
921	1	83	ASN	CB	C	42.410	0.005
922	1	83	ASN	N	N	121.386	0.000
923	1	83	ASN	ND2	N	111.412	0.001
924	1	84	LEU	H	H	8.810	0.000
925	1	84	LEU	HA	H	4.479	0.016
926	1	84	LEU	HB2	H	1.669	0.000
927	1	84	LEU	HB3	H	1.574	0.000
928	1	84	LEU	HG	H	1.695	0.000
929	1	84	LEU	HD11	H	0.936	0.000
930	1	84	LEU	HD12	H	0.936	0.000
931	1	84	LEU	HD13	H	0.936	0.000
932	1	84	LEU	HD21	H	0.826	0.000
933	1	84	LEU	HD22	H	0.826	0.000
934	1	84	LEU	HD23	H	0.826	0.000
935	1	84	LEU	CA	C	56.185	0.000
936	1	84	LEU	CB	C	42.279	0.004
937	1	84	LEU	CG	C	26.860	0.000
938	1	84	LEU	CD1	C	25.463	0.000
939	1	84	LEU	CD2	C	23.685	0.000
940	1	84	LEU	N	N	121.221	0.000
941	1	85	ALA	H	H	8.792	0.000
942	1	85	ALA	HA	H	4.581	0.000
943	1	85	ALA	HB1	H	1.407	0.000
944	1	85	ALA	HB2	H	1.407	0.000
945	1	85	ALA	HB3	H	1.407	0.000
946	1	85	ALA	CA	C	52.298	0.000
947	1	85	ALA	CB	C	19.569	0.000
948	1	85	ALA	N	N	126.294	0.000
949	1	86	LYS	HA	H	4.509	0.000
950	1	86	LYS	HG2	H	1.236	0.000
951	1	86	LYS	HG3	H	1.201	0.000
952	1	86	LYS	HD2	H	1.455	0.000
953	1	86	LYS	HD3	H	1.368	0.000
954	1	86	LYS	HE2	H	2.672	0.000
955	1	86	LYS	HE3	H	2.672	0.000
956	1	86	LYS	CA	C	57.398	0.000
957	1	86	LYS	CG	C	24.788	0.003
958	1	86	LYS	CD	C	29.217	0.006
959	1	86	LYS	CE	C	42.055	0.000
960	1	87	PRO	HA	H	4.322	0.014
961	1	87	PRO	HB2	H	2.119	0.000
962	1	87	PRO	HB3	H	1.777	0.000
963	1	87	PRO	HG2	H	1.953	0.000
964	1	87	PRO	HG3	H	1.874	0.000
965	1	87	PRO	HD2	H	3.733	0.000
966	1	87	PRO	HD3	H	3.547	0.000
967	1	87	PRO	CA	C	62.993	0.000
968	1	87	PRO	CB	C	31.969	0.004
969	1	87	PRO	CG	C	27.591	0.003
970	1	87	PRO	CD	C	50.387	0.001
971	1	88	MET	H	H	8.226	0.000
972	1	88	MET	HA	H	4.357	0.000
973	1	88	MET	HG2	H	1.844	0.000
974	1	88	MET	HG3	H	1.751	0.000
975	1	88	MET	HE1	H	1.788	0.014
976	1	88	MET	HE2	H	1.788	0.014
977	1	88	MET	HE3	H	1.788	0.014
978	1	88	MET	CA	C	56.969	0.000
979	1	88	MET	CG	C	33.815	0.007
980	1	88	MET	CE	C	17.053	0.018
981	1	88	MET	N	N	120.937	0.000
982	1	89	ARG	H	H	8.210	0.000
983	1	89	ARG	HA	H	4.311	0.000
984	1	89	ARG	HB2	H	1.704	0.000
985	1	89	ARG	HB3	H	1.640	0.000
986	1	89	ARG	HG2	H	1.502	0.000
987	1	89	ARG	HG3	H	1.448	0.000
988	1	89	ARG	HD2	H	3.038	0.000
989	1	89	ARG	HD3	H	3.038	0.000
990	1	89	ARG	CA	C	55.518	0.000
991	1	89	ARG	CB	C	30.819	0.006
992	1	89	ARG	CG	C	27.189	0.005
993	1	89	ARG	CD	C	43.377	0.000
994	1	89	ARG	N	N	120.310	0.000
995	1	90	ILE	H	H	8.128	0.000
996	1	90	ILE	HA	H	4.105	0.016
997	1	90	ILE	HB	H	1.760	0.021
998	1	90	ILE	HG12	H	1.369	0.017
999	1	90	ILE	HG13	H	1.057	0.015
1000	1	90	ILE	HG21	H	0.803	0.016
1001	1	90	ILE	HG22	H	0.803	0.016
1002	1	90	ILE	HG23	H	0.803	0.016
1003	1	90	ILE	HD11	H	0.754	0.008
1004	1	90	ILE	HD12	H	0.754	0.008
1005	1	90	ILE	HD13	H	0.754	0.008
1006	1	90	ILE	CA	C	60.874	0.000
1007	1	90	ILE	CB	C	38.810	0.000
1008	1	90	ILE	CG1	C	27.339	0.027
1009	1	90	ILE	CG2	C	17.634	0.004
1010	1	90	ILE	CD1	C	12.912	0.015
1011	1	90	ILE	N	N	122.294	0.000
1012	1	91	LYS	H	H	8.373	0.000
1013	1	91	LYS	HA	H	4.247	0.000
1014	1	91	LYS	HB2	H	1.762	0.000
1015	1	91	LYS	HB3	H	1.677	0.000
1016	1	91	LYS	HG2	H	1.374	0.000
1017	1	91	LYS	HG3	H	1.329	0.000
1018	1	91	LYS	HD2	H	1.588	0.000
1019	1	91	LYS	HD3	H	1.533	0.000
1020	1	91	LYS	HE2	H	2.948	0.000
1021	1	91	LYS	HE3	H	2.948	0.000
1022	1	91	LYS	CA	C	56.332	0.000
1023	1	91	LYS	CB	C	33.166	0.000
1024	1	91	LYS	CG	C	24.855	0.009
1025	1	91	LYS	CD	C	29.114	0.010
1026	1	91	LYS	CE	C	42.189	0.000
1027	1	91	LYS	N	N	125.780	0.000
1028	1	92	GLU	H	H	8.481	0.000
1029	1	92	GLU	HA	H	4.226	0.000
1030	1	92	GLU	HB2	H	2.013	0.000
1031	1	92	GLU	HB3	H	1.928	0.000
1032	1	92	GLU	HG2	H	2.237	0.000
1033	1	92	GLU	HG3	H	2.237	0.000
1034	1	92	GLU	CA	C	57.080	0.000
1035	1	92	GLU	CB	C	30.248	0.017
1036	1	92	GLU	CG	C	36.363	0.000
1037	1	92	GLU	N	N	123.222	0.000
1038	1	93	GLY	H	H	8.493	0.000
1039	1	93	GLY	HA2	H	4.019	0.000
1040	1	93	GLY	HA3	H	3.905	0.000
1041	1	93	GLY	CA	C	45.550	0.013
1042	1	93	GLY	N	N	110.626	0.000
1043	1	94	SER	H	H	8.147	0.000
1044	1	94	SER	HA	H	4.493	0.000
1045	1	94	SER	HB2	H	3.862	0.005
1046	1	94	SER	HB3	H	3.862	0.005
1047	1	94	SER	CA	C	58.269	0.000
1048	1	94	SER	CB	C	64.007	0.000
1049	1	94	SER	N	N	115.486	0.000
1050	1	95	SER	HA	H	4.448	0.000
1051	1	95	SER	HB2	H	3.833	0.000
1052	1	95	SER	HB3	H	3.833	0.000
1053	1	95	SER	CA	C	58.388	0.000
1054	1	95	SER	CB	C	63.958	0.000
1055	1	96	ARG	H	H	8.134	0.000
1056	1	96	ARG	HA	H	4.513	0.000
1057	1	96	ARG	HB2	H	1.727	0.000
1058	1	96	ARG	HB3	H	1.605	0.000
1059	1	96	ARG	HG2	H	1.537	0.000
1060	1	96	ARG	HG3	H	1.537	0.000
1061	1	96	ARG	HD2	H	3.074	0.000
1062	1	96	ARG	HD3	H	3.074	0.000
1063	1	96	ARG	CA	C	53.917	0.000
1064	1	96	ARG	CB	C	30.402	0.013
1065	1	96	ARG	CG	C	26.731	0.000
1066	1	96	ARG	CD	C	43.428	0.000
1067	1	96	ARG	N	N	123.182	0.000
1068	1	97	PRO	HA	H	4.300	0.015
1069	1	97	PRO	HB2	H	1.895	0.000
1070	1	97	PRO	HB3	H	1.317	0.000
1071	1	97	PRO	HG2	H	1.796	0.000
1072	1	97	PRO	HG3	H	1.775	0.000
1073	1	97	PRO	HD2	H	3.662	0.000
1074	1	97	PRO	HD3	H	3.426	0.000
1075	1	97	PRO	CA	C	62.874	0.000
1076	1	97	PRO	CB	C	31.809	0.005
1077	1	97	PRO	CG	C	27.410	0.001
1078	1	97	PRO	CD	C	50.529	0.002
1079	1	98	VAL	H	H	8.027	0.000
1080	1	98	VAL	HA	H	3.979	0.018
1081	1	98	VAL	HB	H	1.925	0.015
1082	1	98	VAL	HG11	H	0.788	0.000
1083	1	98	VAL	HG12	H	0.788	0.000
1084	1	98	VAL	HG13	H	0.788	0.000
1085	1	98	VAL	HG21	H	0.800	0.011
1086	1	98	VAL	HG22	H	0.800	0.011
1087	1	98	VAL	HG23	H	0.800	0.011
1088	1	98	VAL	CA	C	62.387	0.000
1089	1	98	VAL	CB	C	32.781	0.000
1090	1	98	VAL	CG1	C	20.415	0.000
1091	1	98	VAL	CG2	C	21.220	0.020
1092	1	98	VAL	N	N	119.480	0.000
1093	1	99	TRP	H	H	7.819	0.001
1094	1	99	TRP	HA	H	4.699	0.000
1095	1	99	TRP	HB2	H	3.122	0.000
1096	1	99	TRP	HB3	H	3.122	0.000
1097	1	99	TRP	HD1	H	7.109	0.007
1098	1	99	TRP	HE1	H	10.090	0.000
1099	1	99	TRP	HE3	H	7.011	0.011
1100	1	99	TRP	HZ2	H	7.364	0.000
1101	1	99	TRP	HZ3	H	6.964	0.000
1102	1	99	TRP	HH2	H	7.430	0.004
1103	1	99	TRP	CA	C	56.947	0.000
1104	1	99	TRP	CB	C	29.871	0.000
1105	1	99	TRP	CD1	C	127.182	0.000
1106	1	99	TRP	CE3	C	124.500	0.000
1107	1	99	TRP	CZ2	C	114.560	0.000
1108	1	99	TRP	CZ3	C	121.873	0.000
1109	1	99	TRP	CH2	C	120.794	0.000
1110	1	99	TRP	N	N	122.572	0.000
1111	1	99	TRP	NE1	N	129.629	0.000
1112	1	100	SER	H	H	8.040	0.000
1113	1	100	SER	HA	H	4.416	0.000
1114	1	100	SER	HB2	H	3.806	0.000
1115	1	100	SER	HB3	H	3.655	0.000
1116	1	100	SER	CA	C	57.939	0.000
1117	1	100	SER	CB	C	64.375	0.003
1118	1	100	SER	N	N	116.805	0.000
1119	1	101	ASP	H	H	8.267	0.000
1120	1	101	ASP	HA	H	4.584	0.000
1121	1	101	ASP	HB2	H	2.741	0.000
1122	1	101	ASP	HB3	H	2.629	0.000
1123	1	101	ASP	CA	C	54.943	0.000
1124	1	101	ASP	CB	C	41.386	0.001
1125	1	101	ASP	N	N	122.800	0.000
1126	1	102	ASP	H	H	8.267	0.000
1127	1	102	ASP	HA	H	4.310	0.000
1128	1	102	ASP	CA	C	55.270	0.000
1129	1	102	ASP	N	N	120.088	0.000
1130	1	103	ASP	H	H	8.376	0.000
1131	1	103	ASP	HA	H	4.482	0.000
1132	1	103	ASP	HB2	H	2.586	0.000
1133	1	103	ASP	HB3	H	2.586	0.000
1134	1	103	ASP	CA	C	55.684	0.000
1135	1	103	ASP	CB	C	41.177	0.000
1136	1	103	ASP	N	N	122.552	0.000
1137	1	104	TRP	H	H	8.017	0.000
1138	1	104	TRP	HA	H	4.295	0.000
1139	1	104	TRP	HB2	H	3.309	0.000
1140	1	104	TRP	HB3	H	3.309	0.000
1141	1	104	TRP	HD1	H	7.289	0.000
1142	1	104	TRP	HE1	H	10.073	0.000
1143	1	104	TRP	HE3	H	7.083	0.000
1144	1	104	TRP	HZ2	H	7.315	0.000
1145	1	104	TRP	HZ3	H	6.950	0.000
1146	1	104	TRP	HH2	H	7.453	0.000
1147	1	104	TRP	CA	C	59.695	0.000
1148	1	104	TRP	CB	C	29.054	0.000
1149	1	104	TRP	CD1	C	127.249	0.000
1150	1	104	TRP	CE3	C	124.471	0.000
1151	1	104	TRP	CZ2	C	114.591	0.000
1152	1	104	TRP	CZ3	C	121.897	0.000
1153	1	104	TRP	CH2	C	120.722	0.000
1154	1	104	TRP	N	N	121.032	0.000
1155	1	104	TRP	NE1	N	129.639	0.000
1156	1	105	LEU	H	H	7.787	0.000
1157	1	105	LEU	HA	H	3.933	0.000
1158	1	105	LEU	HB2	H	1.508	0.000
1159	1	105	LEU	HB3	H	1.447	0.000
1160	1	105	LEU	HG	H	1.342	0.000
1161	1	105	LEU	HD11	H	0.720	0.000
1162	1	105	LEU	HD12	H	0.720	0.000
1163	1	105	LEU	HD13	H	0.720	0.000
1164	1	105	LEU	HD21	H	0.799	0.000
1165	1	105	LEU	HD22	H	0.799	0.000
1166	1	105	LEU	HD23	H	0.799	0.000
1167	1	105	LEU	CA	C	56.770	0.000
1168	1	105	LEU	CB	C	41.929	0.007
1169	1	105	LEU	CG	C	26.964	0.000
1170	1	105	LEU	CD1	C	23.861	0.000
1171	1	105	LEU	CD2	C	24.978	0.000
1172	1	105	LEU	N	N	119.708	0.000
1173	1	106	LYS	H	H	7.769	0.000
1174	1	106	LYS	HA	H	4.047	0.000
1175	1	106	LYS	HB2	H	1.765	0.000
1176	1	106	LYS	HB3	H	1.765	0.000
1177	1	106	LYS	HG2	H	1.427	0.000
1178	1	106	LYS	HG3	H	1.326	0.000
1179	1	106	LYS	HD2	H	1.627	0.000
1180	1	106	LYS	HD3	H	1.627	0.000
1181	1	106	LYS	HE2	H	2.912	0.000
1182	1	106	LYS	HE3	H	2.912	0.000
1183	1	106	LYS	CA	C	57.833	0.000
1184	1	106	LYS	CB	C	32.548	0.000
1185	1	106	LYS	CG	C	25.231	0.011
1186	1	106	LYS	CD	C	29.174	0.000
1187	1	106	LYS	CE	C	42.246	0.000
1188	1	106	LYS	N	N	119.127	0.000
1189	1	107	LYS	H	H	7.709	0.000
1190	1	107	LYS	HA	H	4.044	0.000
1191	1	107	LYS	HB2	H	1.498	0.000
1192	1	107	LYS	HB3	H	1.447	0.000
1193	1	107	LYS	HG2	H	1.143	0.000
1194	1	107	LYS	HG3	H	1.062	0.000
1195	1	107	LYS	HD2	H	1.424	0.000
1196	1	107	LYS	HD3	H	1.424	0.000
1197	1	107	LYS	HE2	H	2.763	0.000
1198	1	107	LYS	HE3	H	2.763	0.000
1199	1	107	LYS	CA	C	57.365	0.000
1200	1	107	LYS	CB	C	32.748	0.006
1201	1	107	LYS	CG	C	24.736	0.009
1202	1	107	LYS	CD	C	29.073	0.000
1203	1	107	LYS	CE	C	42.063	0.000
1204	1	107	LYS	N	N	119.299	0.000
1205	1	108	PHE	H	H	7.931	0.000
1206	1	108	PHE	HA	H	4.538	0.000
1207	1	108	PHE	HB2	H	3.027	0.000
1208	1	108	PHE	HB3	H	2.645	0.000
1209	1	108	PHE	HD1	H	7.103	0.000
1210	1	108	PHE	HD2	H	7.103	0.000
1211	1	108	PHE	HE1	H	7.163	0.000
1212	1	108	PHE	HE2	H	7.163	0.000
1213	1	108	PHE	HZ	H	7.291	0.000
1214	1	108	PHE	CA	C	57.998	0.000
1215	1	108	PHE	CB	C	39.406	0.001
1216	1	108	PHE	CD1	C	131.930	0.000
1217	1	108	PHE	CE1	C	131.256	0.000
1218	1	108	PHE	CZ	C	129.727	0.000
1219	1	108	PHE	N	N	118.842	0.000
1220	1	109	SER	H	H	7.977	0.000
1221	1	109	SER	HA	H	4.359	0.000
1222	1	109	SER	HB2	H	3.860	0.000
1223	1	109	SER	HB3	H	3.860	0.000
1224	1	109	SER	CA	C	58.820	0.000
1225	1	109	SER	CB	C	62.649	0.000
1226	1	109	SER	N	N	116.188	0.000
1227	1	110	GLY	H	H	8.049	0.000
1228	1	110	GLY	HA2	H	3.907	0.000
1229	1	110	GLY	HA3	H	3.907	0.000
1230	1	110	GLY	CA	C	45.563	0.000
1231	1	110	GLY	N	N	110.337	0.000
1232	1	111	LYS	H	H	8.046	0.000
1233	1	111	LYS	HA	H	4.370	0.000
1234	1	111	LYS	HG2	H	1.398	0.000
1235	1	111	LYS	HG3	H	1.357	0.000
1236	1	111	LYS	HD2	H	1.687	0.000
1237	1	111	LYS	HD3	H	1.628	0.000
1238	1	111	LYS	HE2	H	2.942	0.000
1239	1	111	LYS	HE3	H	2.942	0.000
1240	1	111	LYS	CA	C	56.225	0.000
1241	1	111	LYS	CG	C	24.776	0.001
1242	1	111	LYS	CD	C	29.323	0.006
1243	1	111	LYS	CE	C	42.363	0.000
1244	1	111	LYS	N	N	120.705	0.000
1245	1	112	THR	H	H	8.173	0.000
1246	1	112	THR	HA	H	4.269	0.000
1247	1	112	THR	HB	H	4.185	0.000
1248	1	112	THR	HG21	H	1.173	0.000
1249	1	112	THR	HG22	H	1.173	0.000
1250	1	112	THR	HG23	H	1.173	0.000
1251	1	112	THR	CA	C	62.005	0.000
1252	1	112	THR	CB	C	69.837	0.000
1253	1	112	THR	CG2	C	21.787	0.000
1254	1	112	THR	N	N	115.605	0.000
1255	1	113	LEU	H	H	8.246	0.000
1256	1	113	LEU	HB2	H	1.610	0.000
1257	1	113	LEU	HB3	H	1.576	0.000
1258	1	113	LEU	HG	H	1.577	0.000
1259	1	113	LEU	HD11	H	0.878	0.000
1260	1	113	LEU	HD12	H	0.878	0.000
1261	1	113	LEU	HD13	H	0.878	0.000
1262	1	113	LEU	HD21	H	0.878	0.000
1263	1	113	LEU	HD22	H	0.878	0.000
1264	1	113	LEU	HD23	H	0.878	0.000
1265	1	113	LEU	CB	C	42.366	0.009
1266	1	113	LEU	CG	C	27.069	0.000
1267	1	113	LEU	CD1	C	24.967	0.000
1268	1	113	LEU	N	N	124.358	0.000
1269	1	114	GLU	H	H	8.315	0.000
1270	1	114	GLU	HA	H	4.226	0.000
1271	1	114	GLU	HB2	H	2.017	0.000
1272	1	114	GLU	HB3	H	1.901	0.000
1273	1	114	GLU	HG2	H	2.239	0.000
1274	1	114	GLU	HG3	H	2.239	0.000
1275	1	114	GLU	CA	C	56.765	0.000
1276	1	114	GLU	CB	C	30.465	0.022
1277	1	114	GLU	CG	C	36.387	0.000
1278	1	114	GLU	N	N	121.580	0.000
1279	1	115	GLU	H	H	8.319	0.000
1280	1	115	GLU	HA	H	4.240	0.000
1281	1	115	GLU	HB2	H	2.000	0.000
1282	1	115	GLU	HB3	H	2.000	0.000
1283	1	115	GLU	HG2	H	2.220	0.000
1284	1	115	GLU	HG3	H	2.220	0.000
1285	1	115	GLU	CA	C	56.497	0.000
1286	1	115	GLU	CB	C	30.455	0.000
1287	1	115	GLU	CG	C	36.451	0.000
1288	1	115	GLU	N	N	121.414	0.000
1289	1	116	ASN	H	H	8.413	0.000
1290	1	116	ASN	HA	H	4.722	0.000
1291	1	116	ASN	HB2	H	2.815	0.000
1292	1	116	ASN	HB3	H	2.695	0.000
1293	1	116	ASN	HD21	H	7.548	0.000
1294	1	116	ASN	HD22	H	6.881	0.000
1295	1	116	ASN	CA	C	53.099	0.000
1296	1	116	ASN	CB	C	38.990	0.007
1297	1	116	ASN	N	N	120.219	0.000
1298	1	116	ASN	ND2	N	112.873	0.001
1299	1	117	LYS	H	H	7.811	0.000
1300	1	117	LYS	HA	H	4.138	0.000
1301	1	117	LYS	HB2	H	1.797	0.000
1302	1	117	LYS	HB3	H	1.673	0.000
1303	1	117	LYS	HD2	H	1.628	0.000
1304	1	117	LYS	HD3	H	1.628	0.000
1305	1	117	LYS	CA	C	57.733	0.000
1306	1	117	LYS	CB	C	33.868	0.006
1307	1	117	LYS	CD	C	29.317	0.000
1308	1	117	LYS	N	N	126.734	0.000
1309	2	1	A	H1'	H	5.949	0.000
1310	2	1	A	H2	H	8.062	0.000
1311	2	1	A	H2'	H	4.800	0.000
1312	2	1	A	H3'	H	4.744	0.000
1313	2	1	A	H4'	H	4.417	0.000
1314	2	1	A	H5'	H	3.873	0.000
1315	2	1	A	H5''	H	3.855	0.000
1316	2	1	A	H8	H	8.252	0.000
1317	2	1	A	C1'	C	91.677	0.000
1318	2	1	A	C2	C	154.993	0.000
1319	2	1	A	C2'	C	75.701	0.000
1320	2	1	A	C3'	C	76.878	0.000
1321	2	1	A	C4'	C	86.950	0.000
1322	2	1	A	C5'	C	63.834	0.000
1323	2	1	A	C8	C	141.841	0.000
1324	2	2	A	H1'	H	5.971	0.006
1325	2	2	A	H2	H	8.084	0.000
1326	2	2	A	H2'	H	4.783	0.000
1327	2	2	A	H3'	H	4.849	0.000
1328	2	2	A	H4'	H	4.567	0.000
1329	2	2	A	H5'	H	4.362	0.000
1330	2	2	A	H5''	H	4.252	0.000
1331	2	2	A	H8	H	8.288	0.000
1332	2	2	A	C1'	C	89.977	0.004
1333	2	2	A	C2	C	155.374	0.000
1334	2	2	A	C2'	C	76.195	0.000
1335	2	2	A	C3'	C	76.668	0.000
1336	2	2	A	C4'	C	85.231	0.000
1337	2	2	A	C5'	C	67.441	0.013
1338	2	2	A	C8	C	141.716	0.000
1339	2	3	U	H1'	H	5.843	0.000
1340	2	3	U	H2'	H	4.370	0.000
1341	2	3	U	H3'	H	4.650	0.000
1342	2	3	U	H4'	H	4.457	0.000
1343	2	3	U	H5	H	5.738	0.000
1344	2	3	U	H5'	H	4.259	0.000
1345	2	3	U	H5''	H	4.175	0.000
1346	2	3	U	H6	H	7.727	0.000
1347	2	3	U	C1'	C	91.022	0.000
1348	2	3	U	C2'	C	75.748	0.000
1349	2	3	U	C3'	C	76.605	0.000
1350	2	3	U	C4'	C	84.984	0.000
1351	2	3	U	C5	C	105.139	0.000
1352	2	3	U	C5'	C	67.636	0.027
1353	2	3	U	C6	C	143.567	0.000
1354	2	4	A	H1'	H	5.870	0.000
1355	2	4	A	H2	H	8.030	0.000
1356	2	4	A	H2'	H	4.746	0.000
1357	2	4	A	H3'	H	4.758	0.000
1358	2	4	A	H4'	H	4.526	0.000
1359	2	4	A	H5'	H	4.284	0.000
1360	2	4	A	H5''	H	4.193	0.000
1361	2	4	A	H8	H	8.246	0.000
1362	2	4	A	C1'	C	90.941	0.000
1363	2	4	A	C2	C	155.178	0.000
1364	2	4	A	C2'	C	76.099	0.000
1365	2	4	A	C3'	C	76.386	0.000
1366	2	4	A	C4'	C	84.718	0.000
1367	2	4	A	C5'	C	67.650	0.012
1368	2	4	A	C8	C	143.153	0.000
1369	2	5	A	H1'	H	5.896	0.000
1370	2	5	A	H2	H	7.909	0.000
1371	2	5	A	H2'	H	4.641	0.000
1372	2	5	A	H3'	H	4.813	0.000
1373	2	5	A	H4'	H	4.527	0.000
1374	2	5	A	H5'	H	4.383	0.000
1375	2	5	A	H5''	H	4.233	0.000
1376	2	5	A	H8	H	8.194	0.000
1377	2	5	A	C1'	C	90.852	0.000
1378	2	5	A	C2	C	154.878	0.000
1379	2	5	A	C2'	C	76.402	0.000
1380	2	5	A	C3'	C	75.483	0.000
1381	2	5	A	C4'	C	84.398	0.000
1382	2	5	A	C5'	C	66.979	0.000
1383	2	5	A	C8	C	141.324	0.000
1384	2	6	A	H1'	H	6.004	0.000
1385	2	6	A	H2	H	8.131	0.000
1386	2	6	A	H2'	H	4.535	0.000
1387	2	6	A	H3'	H	4.502	0.000
1388	2	6	A	H4'	H	4.392	0.000
1389	2	6	A	H5'	H	4.381	0.000
1390	2	6	A	H5''	H	4.217	0.000
1391	2	6	A	H8	H	8.260	0.000
1392	2	6	A	C1'	C	90.448	0.000
1393	2	6	A	C2	C	155.413	0.000
1394	2	6	A	C2'	C	77.399	0.000
1395	2	6	A	C3'	C	72.254	0.000
1396	2	6	A	C4'	C	85.762	0.000
1397	2	6	A	C5'	C	67.278	0.029
1398	2	6	A	C8	C	141.726	0.000

Release date

2022-04-05

Citation

RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription
Blatter, M., Meylan, C., Clery, A., Giambruno, R., Nikolaev, Y., Heidecker, M., Solanki, J.A., Diaz, M.O., Gabellini, D., Allain, F.H.
Sci. Adv. (2023), 9, eadf5330-eadf5330, PubMed 37075125 , DOI 10.1126/sciadv.adf5330 , Abstract