BMRB: 34809

Why does the herpes simplex 1 virus-encoded UL49.5 protein fail to inhibit the TAP-dependent antigen presentation?

Authors

Zhukov, I., Krupa, P., Karska, N., Rodziewicz-Motowidlo, S., Lipinska, A.D.

Assembly

Envelope glycoprotein N

Entity

1. Envelope glycoprotein N (polymer, Thiol state: not present), 35 monomers, 3376.478 Da Detail

DAGPRGEPPG EEGGRDGIGG ARXETQNTGQ XSAPG

Formula weight

3376.478 Da

Source organism

Human alphaherpesvirus 1

Exptl. method

solution NMR

Data set

assigned_chemical_shifts

Chemcal Shifts

¹H: 164 assignments Detail

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• BMRB/XML (partial)
• CSV
• TSV

ID	Entity ID	Seq ID	Comp ID	Atom ID	Atom type	Val	Val err	Ambig. code
1	1	1	ASP	HA	H	4.252	0.00	1
2	1	1	ASP	HB2	H	2.880	0.01	1
3	1	1	ASP	HB3	H	2.824	0.00	1
4	1	2	ALA	H	H	8.649	0.00	1
5	1	2	ALA	HA	H	4.396	0.00	1
6	1	2	ALA	HB1	H	1.386	0.00	1
7	1	2	ALA	HB2	H	1.386	0.00	1
8	1	2	ALA	HB3	H	1.386	0.00	1
9	1	3	GLY	H	H	8.180	0.00	1
10	1	3	GLY	HA2	H	3.922	0.00	2
11	1	3	GLY	HA3	H	3.922	0.00	2
12	1	5	ARG	H	H	8.201	0.00	1
13	1	5	ARG	HA	H	4.308	0.00	1
14	1	5	ARG	HB2	H	1.840	0.01	1
15	1	5	ARG	HB3	H	1.744	0.00	1
16	1	5	ARG	HG2	H	1.852	0.00	1
17	1	5	ARG	HG3	H	1.741	0.00	1
18	1	5	ARG	HD2	H	3.170	0.00	2
19	1	5	ARG	HD3	H	3.170	0.00	2
20	1	6	GLY	H	H	8.286	0.00	1
21	1	6	GLY	HA2	H	3.922	0.01	2
22	1	6	GLY	HA3	H	3.922	0.01	2
23	1	7	GLU	H	H	8.077	0.00	1
24	1	7	GLU	HA	H	4.357	0.00	1
25	1	7	GLU	HB2	H	2.103	0.00	1
26	1	7	GLU	HB3	H	1.949	0.00	1
27	1	7	GLU	HG2	H	2.404	0.00	2
28	1	7	GLU	HG3	H	2.404	0.00	2
29	1	9	PRO	HA	H	4.232	0.00	1
30	1	9	PRO	HD2	H	3.623	0.00	2
31	1	9	PRO	HD3	H	3.623	0.00	2
32	1	10	GLY	H	H	8.777	0.00	1
33	1	10	GLY	HA2	H	4.007	0.00	2
34	1	10	GLY	HA3	H	4.007	0.00	2
35	1	11	GLU	H	H	8.363	0.00	1
36	1	11	GLU	HA	H	4.419	0.00	1
37	1	11	GLU	HB2	H	1.969	0.00	2
38	1	11	GLU	HB3	H	1.969	0.00	2
39	1	11	GLU	HG2	H	2.332	0.00	2
40	1	11	GLU	HG3	H	2.332	0.00	2
41	1	12	GLU	H	H	8.105	0.00	1
42	1	13	GLY	H	H	8.404	0.00	1
43	1	13	GLY	HA2	H	3.935	0.00	2
44	1	13	GLY	HA3	H	3.935	0.00	2
45	1	14	GLY	H	H	8.446	0.01	1
46	1	14	GLY	HA2	H	3.873	0.00	2
47	1	14	GLY	HA3	H	3.873	0.00	2
48	1	15	ARG	H	H	8.451	0.00	1
49	1	15	ARG	HA	H	4.318	0.00	1
50	1	15	ARG	HB2	H	1.852	0.01	1
51	1	15	ARG	HB3	H	1.757	0.00	1
52	1	15	ARG	HG2	H	1.639	0.00	2
53	1	15	ARG	HG3	H	1.639	0.00	2
54	1	15	ARG	HD2	H	3.183	0.00	2
55	1	15	ARG	HD3	H	3.183	0.00	2
56	1	15	ARG	HE	H	7.154	0.00	1
57	1	16	ASP	H	H	8.455	0.00	1
58	1	16	ASP	HA	H	4.660	0.00	1
59	1	16	ASP	HB2	H	2.859	0.00	1
60	1	16	ASP	HB3	H	2.783	0.00	1
61	1	17	GLY	H	H	8.220	0.00	1
62	1	17	GLY	HA2	H	3.932	0.01	2
63	1	17	GLY	HA3	H	3.932	0.01	2
64	1	18	ILE	H	H	7.956	0.00	1
65	1	18	ILE	HA	H	4.168	0.00	1
66	1	18	ILE	HB	H	1.877	0.00	1
67	1	18	ILE	HG12	H	0.890	0.00	1
68	1	18	ILE	HG13	H	0.827	0.00	1
69	1	18	ILE	HG21	H	1.144	0.00	1
70	1	18	ILE	HG22	H	1.144	0.00	1
71	1	18	ILE	HG23	H	1.144	0.00	1
72	1	18	ILE	HD11	H	0.888	0.00	1
73	1	18	ILE	HD12	H	0.888	0.00	1
74	1	18	ILE	HD13	H	0.888	0.00	1
75	1	19	GLY	H	H	8.508	0.01	1
76	1	19	GLY	HA2	H	3.929	0.00	2
77	1	19	GLY	HA3	H	3.929	0.00	2
78	1	20	GLY	H	H	8.416	0.00	1
79	1	20	GLY	HA2	H	3.926	0.01	2
80	1	20	GLY	HA3	H	3.926	0.01	2
81	1	21	ALA	H	H	8.123	0.01	1
82	1	21	ALA	HA	H	4.284	0.01	1
83	1	21	ALA	HB1	H	1.351	0.00	1
84	1	21	ALA	HB2	H	1.351	0.00	1
85	1	21	ALA	HB3	H	1.351	0.00	1
86	1	22	ARG	H	H	8.245	0.01	1
87	1	22	ARG	HA	H	4.296	0.00	1
88	1	22	ARG	HB2	H	1.820	0.01	1
89	1	22	ARG	HB3	H	1.748	0.00	1
90	1	22	ARG	HG2	H	1.609	0.00	2
91	1	22	ARG	HG3	H	1.609	0.00	2
92	1	22	ARG	HD2	H	3.172	0.00	2
93	1	22	ARG	HD3	H	3.172	0.00	2
94	1	22	ARG	HE	H	7.150	0.00	1
95	1	23	ABA	H	H	8.263	0.00	1
96	1	23	ABA	HA	H	4.275	0.00	1
97	1	23	ABA	HB2	H	1.271	0.01	2
98	1	23	ABA	HB3	H	1.271	0.01	2
99	1	23	ABA	HG2	H	0.838	0.01	2
100	1	23	ABA	HG3	H	0.838	0.01	2
101	1	24	GLU	H	H	8.143	0.00	1
102	1	24	GLU	HA	H	4.325	0.00	1
103	1	24	GLU	HB2	H	2.071	0.01	1
104	1	24	GLU	HB3	H	1.938	0.01	1
105	1	24	GLU	HG2	H	2.318	0.01	2
106	1	24	GLU	HG3	H	2.318	0.01	2
107	1	25	THR	H	H	8.162	0.00	1
108	1	25	THR	HA	H	4.293	0.00	1
109	1	25	THR	HB	H	4.175	0.00	1
110	1	25	THR	HG21	H	1.175	0.00	1
111	1	25	THR	HG22	H	1.175	0.00	1
112	1	25	THR	HG23	H	1.175	0.00	1
113	1	26	GLN	H	H	8.374	0.01	1
114	1	26	GLN	HA	H	4.346	0.00	1
115	1	26	GLN	HB2	H	2.100	0.01	1
116	1	26	GLN	HB3	H	1.969	0.00	1
117	1	26	GLN	HG2	H	2.430	0.00	2
118	1	26	GLN	HG3	H	2.430	0.00	2
119	1	26	GLN	HE21	H	7.451	0.00	2
120	1	26	GLN	HE22	H	7.451	0.00	2
121	1	27	ASN	H	H	8.491	0.01	1
122	1	27	ASN	HA	H	4.768	0.00	1
123	1	27	ASN	HB2	H	2.839	0.01	1
124	1	27	ASN	HB3	H	2.760	0.00	1
125	1	27	ASN	HD21	H	7.556	0.00	2
126	1	27	ASN	HD22	H	7.556	0.00	2
127	1	28	THR	H	H	8.106	0.00	1
128	1	28	THR	HA	H	4.296	0.00	1
129	1	28	THR	HB	H	4.187	0.00	1
130	1	28	THR	HG21	H	1.165	0.00	1
131	1	28	THR	HG22	H	1.165	0.00	1
132	1	28	THR	HG23	H	1.165	0.00	1
133	1	29	GLY	H	H	8.270	0.02	1
134	1	29	GLY	HA2	H	3.891	0.00	2
135	1	29	GLY	HA3	H	3.891	0.00	2
136	1	30	GLN	H	H	8.088	0.00	1
137	1	30	GLN	HA	H	4.666	0.00	1
138	1	30	GLN	HB2	H	2.029	0.01	1
139	1	30	GLN	HB3	H	1.846	0.00	1
140	1	30	GLN	HG2	H	2.423	0.01	2
141	1	30	GLN	HG3	H	2.423	0.01	2
142	1	31	NLE	H	H	8.170	0.00	1
143	1	31	NLE	HA	H	4.186	0.00	1
144	1	31	NLE	HB2	H	1.785	0.01	2
145	1	31	NLE	HB3	H	1.785	0.01	2
146	1	31	NLE	HD1	H	0.892	0.01	2
147	1	31	NLE	HD2	H	0.892	0.01	2
148	1	31	NLE	HD3	H	0.892	0.01	2
149	1	31	NLE	HG2	H	1.690	0.01	2
150	1	31	NLE	HG3	H	1.690	0.01	2
151	1	32	SER	H	H	8.180	0.00	1
152	1	32	SER	HB2	H	4.097	0.01	1
153	1	32	SER	HB3	H	4.035	0.00	1
154	1	33	ALA	H	H	8.211	0.00	1
155	1	33	ALA	HA	H	4.596	0.01	1
156	1	33	ALA	HB1	H	1.330	0.00	1
157	1	33	ALA	HB2	H	1.330	0.00	1
158	1	33	ALA	HB3	H	1.330	0.00	1
159	1	34	PRO	HA	H	4.675	0.00	1
160	1	34	PRO	HD2	H	3.813	0.00	1
161	1	34	PRO	HD3	H	3.600	0.01	1
162	1	35	GLY	H	H	8.211	0.00	1
163	1	35	GLY	HA2	H	3.805	0.00	2
164	1	35	GLY	HA3	H	3.805	0.00	2

Release date

2023-05-18

Citation

Why does the herpes simplex 1 virus-encoded UL49.5 protein fail to inhibit the TAP-dependent antigen presentation?
Karska, N., Zhukov, I., Lipinska, A.D., Rodziewicz-Motowidlo, S., Krupa, P.
Biochim. Biophys. Acta. Biomembr. (2023), 1865, 184200-184200, PubMed 37517559 , DOI 10.1016/j.bbamem.2023.184200 , Abstract

Related entities 1. Envelope glycoprotein N, : 1 : 1 : 1 entities Detail

Experiments performed 5 experiments Detail

Chemical shift validation 3 contents Detail