A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript
GGACCCAUAA CCCACCUAGA CCCUAGCUUC GGCUAGAGGG UCAACGCGAA AGCGAGGCCG GGUGGGCGGG UACGUCCGCC CUGGGGAGGG GUCC
Polymer type: polyribonucleotide
Total | 1H | 13C | 15N | |
---|---|---|---|---|
All | 81.3 % (1213 of 1492) | 79.6 % (654 of 822) | 85.1 % (530 of 623) | 61.7 % (29 of 47) |
Suger, PO4 | 78.2 % (809 of 1034) | 76.6 % (432 of 564) | 80.2 % (377 of 470) | |
Nucleobase | 88.2 % (404 of 458) | 86.0 % (222 of 258) | 100.0 % (153 of 153) | 61.7 % (29 of 47) |
Aromatic | 91.5 % (366 of 400) | 92.0 % (184 of 200) | 100.0 % (153 of 153) | 61.7 % (29 of 47) |
1. entity 1
GGACCCAUAA CCCACCUAGA CCCUAGCUUC GGCUAGAGGG UCAACGCGAA AGCGAGGCCG GGUGGGCGGG UACGUCCGCC CUGGGGAGGG GUCCSolvent system 95% H2O/5% D2O, Pressure 1 atm, Temperature 298 K, pH 6.0
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | paRNA | [U-99% 13C; U-99% 15N] | 0.75 mM | |
2 | paRNA | [U-99% 13C; U-99% 15N] | 0.75 mM | |
3 | Sodium phosphate | natural abundance | 20 mM |