BMRB: 5139

Solution structure of lactam analogue (DDap) of HIV gp41 600-612 loop

Authors

Phan Chan Du, A., Limal, D., Semetey, V., Dali, H., Jolivet, M., Desgranges, C., Cung, M., Briand, J., Petit, M., Muller, S.

Assembly

DDap (Ace)IWGDSGKLI(DNP)TTA analogue of HIV GP41

Entity

1. DDap (Ace)IWGDSGKLI(DNP)TTA analogue of HIV GP41 (polymer, Thiol state: not present), 14 monomers, 1374.562 Da Detail

XIWGDSGKLI XTTA

Formula weight

1374.562 Da

Source organism

Human immunodeficiency virus

Exptl. method

NMR

Refine. method

torsion angles dynamics, molecular dynamics, energy minimization.

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 85.7 %, Completeness: 97.0 %, Completeness (bb): 100.0 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	97.0 % (64 of 66)	97.0 % (64 of 66)
Backbone	100.0 % (26 of 26)	100.0 % (26 of 26)
Sidechain	95.0 % (38 of 40)	95.0 % (38 of 40)
Aromatic	100.0 % (6 of 6)	100.0 % (6 of 6)
Methyl	88.9 % (8 of 9)	88.9 % (8 of 9)

1. DDap analogue peptide of gp41 600-612 loop

XIWGDSGKLI XTTA

Show sample condition

Sample

Pressure 1 atm, Temperature 298 K

#	Name	Isotope labeling	Type	Concentration
1	DDap analogue peptide of gp41 600-612 loop			2 mM
2	DMSO	[U-2H]		100 %

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Protein Blocks Logo

Calculated from 20 models in PDB: 1JC8, Strand ID: A Detail

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Release date

2015-04-15

Citation

Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein
Du, A.P.C., Limal, D., Semetey, V., Dali, H., Jolivet, M., Desgranges, C., Cung, M.T., Briand, J.P., Petit, M.C., Muller, S.
J. Mol. Biol. (2002), 323, 503-521, PubMed 12381305 , DOI: , Abstract

Related entities 1. DDap (Ace)IWGDSGKLI(DNP)TTA analogue of HIV GP41, : 1 : 1 : 14 entities Detail

Experiments performed 3 experiments Detail