BMRB: 5322

Solution Structure of g-Bungarotoxin, an RGD-Containing Neurotoxin

Authors

Chuang, W.

Assembly

gamma-bungarotoxin monomer

Entity

1. gamma-bungarotoxin monomer (polymer, Thiol state: all disulfide bound), 68 monomers, 7534.617 Da Detail

MQCKTCSFYT CPNSETCPDG KNICVKRSWT AVRGDGPKRE IRRECAATCP PSKLGLTVFC CTTDNCNH

Formula weight

7534.617 Da

Entity Connection

disulfide 5 Detail

---

ID	Type	Value order	Atom ID 1	Atom ID 2
1	disulfide	sing	1:CYS3:SG	1:CYS24:SG
2	disulfide	sing	1:CYS6:SG	1:CYS11:SG
3	disulfide	sing	1:CYS17:SG	1:CYS45:SG
4	disulfide	sing	1:CYS49:SG	1:CYS60:SG
5	disulfide	sing	1:CYS61:SG	1:CYS66:SG

Source organism

Bungarus multicinctus

Exptl. method

NMR

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 97.2 %, Completeness (bb): 98.5 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polypeptide(L)

	Total	1H
All	97.2 % (382 of 393)	97.2 % (382 of 393)
Backbone	98.5 % (133 of 135)	98.5 % (133 of 135)
Sidechain	96.5 % (249 of 258)	96.5 % (249 of 258)
Aromatic	90.9 % (20 of 22)	90.9 % (20 of 22)
Methyl	100.0 % (25 of 25)	100.0 % (25 of 25)

1. gamma bungarotoxin

MQCKTCSFYT CPNSETCPDG KNICVKRSWT AVRGDGPKRE IRRECAATCP PSKLGLTVFC CTTDNCNH

Show sample condition

Sample

Temperature 300 (±0.01) K, pH 5.76 (±0.01)

#	Name	Isotope labeling	Type	Concentration
1	gamma bungarotoxin			2 mM

Hide sample codition

Release date

2002-03-14

Citation

Solution Structure of gamma-bungarotoxin: The functional significance of amino acid residues flanking the RGD motif in integrin binding
Shiu, J., Chen, C., Chang, L., Chen, Y., Chen, Y., Lo, Y., Liu, Y., Chuang, W.
Proteins (2004), PubMed , DOI:

Related entities 1. gamma-bungarotoxin monomer, : 1 : 1 : 2 : 111 entities Detail

Experiments performed 3 experiments Detail

Chemical shift validation 3 contents Detail